Survival Rates of Cervical Cancer Patients in Malaysia (original) (raw)
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Predictive factors associated with survival rate of cervical cancer patients in Brunei Darussalam
Brunei International Medical Journal, 2019
Introduction: Cervical cancer is the third most prevalent cancer among w omen in Brunei Darussalam. This study aims to report the overall survival rates and associated factors of patients diagnosed with malignant cervical cancer in Brunei Darussalam. Methods: A retrospective study of patients diagnosed with cervical cancer from 2007 to 2017 in Brunei Darussalam. The data were obtained from the population-based cancer registry in Brunei Darussalam. Kaplan-Meier survival analysis was used to estimate the overall survival rates at 1-, 3-and 5-year intervals while the log-rank test was used to assess differences in survival between groups. Cox Proportional Hazard (PH) regression analysis was used to examine the association of demographic and clinical factors on the survival of cervical cancer patients. Results: A total of 329 registered malignant cervical cancer cases were analyzed. The mean age at diagnosis of patients with cervical cancer was 46.7 ± 12.2 years. There were 28.6% deaths and the overall survival rates at 1, 3 and 5 years were 85.4%, 72.6% and 68.6% respectively. Age at diagnosis, cancer stage and histology types were significant predictive factors for overall survival of the patients diagnosed with cervical cancers when analysed on both log rank tests and Cox PH model. Conclusion: Age at diagnosis , cancer stage and histology types were significantly associated with the overall survival rates of cervical cancer patients in Brunei Darussalam. Early detection and management of cervical cancer at early stages should be prioritized to improve the survival rate and quality of cancer care.
Asian Journal of Pharmaceutical Research and Health Care, 2020
Cervical cancer is the leading-caused cancer death in women worldwide, especially occurring in the developing countries. The understanding of the incidence, mortality, and their relationship with the Human Development Index (HDI) and its three dimensions, including gross national income per capita, education index, and life expectancy, is crucial to establish the best way to prevent the increasing of cervical cancer in future. The data of the incidence (-ASR), mortality (-ASR), HDI were extracted from the GLOBOCAN and Human Development Reports database. Person Correlation Coefficient was applied to characterize the relationship among them. The incidence and mortality of Cervical Cancer in Southeast Asia (total new cases: 62,456 cases, counting for 19, 81%; new death cases: 35,738, counting for 21.22%), ranked in the top three of Asian regions. There was the negative correlation between the incidence-ASR, mortality-ASR with HDI, and its three dimensions. A significant correlation between the mortality-ASR rate of cervical cancer and Life expectancy at birth was recorded. The cancer of cervix gravitates to Asian region, including Southeast Asian countries. There was a significant relationship between the mortality-ASR rate of cervical cancer and Life expectancy at birth.
Asian Pacific Journal of Cancer Prevention, 2013
Objective: The objective of this study was to determine the five-year survival among patients with cervical cancer treated in Hospital Universiti Sains Malaysia. Methods: One hundred and twenty cervical cancer patients diagnosed between 1 st July 1995 and 30 th June 2007 were identified. Data were obtained from medical records. The survival probability was determined using the Kaplan-Meier method and the log-rank test was applied to compare the survival distribution between groups. Results: The overall five-year survival was 39.7% [95%CI (Confidence Interval): 30.7, 51.3] with a median survival time of 40.8 (95%CI: 34.0, 62.0) months. The log-rank test showed that there were survival differences between the groups for the following variables: stage at diagnosis (p=0.005); and primary treatment (p=0.0242). Patients who were diagnosed at the latest stage (III-IV) were found to have the lowest survival, 18.4% (95%CI: 6.75, 50.1), compared to stage I and II where the five-year survival was 54.7% (95%CI: 38.7, 77.2) and 40.8% (95%CI: 27.7, 60.3), respectively. The five-year survival was higher in patients who received surgery [52.6% (95%CI: 37.5, 73.6)] as a primary treatment compared to the non-surgical group [33.3% (95%CI: 22.9, 48.4)]. Conclusion: The five-year survival of cervical cancer patients in this study was low. The survival of those diagnosed at an advanced stage was low compared to early stages. In addition, those who underwent surgery had higher survival than those who had no surgery for primary treatment.
Survival Rate of Cervical Cancer in National Referral Hospital in 2012 - 2014
Acta medica Indonesiana, 2019
BACKGROUND cervical cancer is the third leading cause of female deaths worldwide, and it is the leading cause of female deaths in developing countries. A routine survival evaluation is required to imply the result of the treatment. The aim of this study was to determine the cervical cancer patient survival rate at the Cipto Mangunkusumo hospital as national referral hospital in Indonesia. METHODS our retrospective cohort study utilized the medical records of cervical cancer patients from 2012 to 2014 using total population sampling method. The data analysis was conducted using the Kaplan-Meier curve, log rank test and Cox regression to determine significant associations between variables. RESULTS there were 1,303 subjects with overall survival rates of cervical cancer up to the fifth year of 76%, 65%, 59%, 43% and 34%, respectively, with a median survival of 1,316 days. There were significant differences of hazard ratio for cancer stage variables (p<0.001), and the Cox regression...
Survival rate of cervical cancer from a study conducted in India
Indian Journal of Medical Sciences, 2020
Objectives: The incidence and mortality rates of cervical cancer in the world are 13.1/105 and 6.9/105, respectively. In India, it is estimated that there are 96,922 new cervical cancer cases and 60,078 deaths and ranked second among women cancers. The incidence and mortality rates are 14.7/105 and 9.2/105, respectively, although the incidence varies within Indian population. The majority of these cervical patients report at a late-stage of disease in health-care facility due to lack of awareness. A premier tertiary cancer hospital in Mumbai conducted the present survival-study. The aim of the study was to assess the various factors that determine the survival outcomes by age at diagnosis, role of comorbidities, stage of disease, and treatment. Material and Methods: The main source of information was patients’ medical records from which the data were abstracted, and active follow-up was undertaken. 1678 cases diagnosed between the years 2006 and 2008 at Tata Memorial Hospital are an...
The Profile of Cervical Cancer Patients at Soedarso Hospital
Indonesian Journal of Cancer
Background: The prevalence and mortality rates of cervical cancer differ by region with the highest rates found in Latin America, Southeast Asia, and Africa. In Indonesia, cervical cancer is the second-largest contributor to the latest cases in 2020. In West Kalimantan, over 20,000 women were diagnosed with cervical cancer in 2014. This study aims to describe the characteristics of cervical cancer patients in West Kalimantan. Methods: A descriptive observational study was conducted on patients from 2017 to 2019 according to the Soedarso Hospital database. All medical records were reviewed and analyzed to obtain the variable data; they were age, ethnics, origin, stage of cervical cancer, histopathology types, and hemoglobin (Hb) level. Results: Cervical cancer patients for the 2017–2019 period totaled 147 people with 30 deaths. In this study, 97 patients from 2017 to 2019 met the inclusion criteria. Cervical cancer was found from the age of 27 years with a peak at the age of 41–60 ye...
Cervical cancer in Brunei Darussalam
Singapore medical journal
Introduction: Cervical cancer caused by the human papilloma virus (HPV) is a common cancer in women. There is no published data on the recent incidence of cervical dysplasia, cervical cancer and genital warts caused by the different types of HPVs in Brunei Darussalam. Methods: A cross-sectional, retrospective study was conducted utilising data from patients diagnosed with cervical cancer during the period 2005-2009 in Brunei Darussalam. The varying incidences of different types of cervical lesions among various ethnic and age groups, and in the overall population, were determined. Results: The mean age-standardised incidence of invasive cervical cancer during the five-year period was 24.9 per 100,000 women per year (95% confidence interval [CI] 21.7, 28.1). Age-specific invasive cervical cancer incidence peaked in the age group 45-59 years. Chinese females tended to have a higher incidence of invasive cervical cancer (28.2 per 100,000 women per year; 95% CI 17.8, 38.7) than Malay fe...
Cervical cancer in Kerala: a hospital registry-based study on survival and prognostic factors
British Journal of Cancer, 1995
The survival experience of 452 cervical cancer patients registered during 1984 by the hospital registry of the Regional Cancer Centre, Trivandrum, Kerala, India, is described in this paper. Eighty per cent of the patients completed the prescribed treatment, which was predominantly radiotherapy. The vital status of each patient was established by scrutiny of case records and by reply-paid postal enquiries. The observed survival rates were estimated by the Kaplan-Meier method and prognostic factors were assessed using Cox's proportional hazards regression analysis. The overall 5 year observed survival rate was 47.4% (95% CI, 41.6-52.9%). Socioeconomic status, performance status and the clinical stage of disease emerged as independent predictors of survival. Low survival was associated with advanced stages of disease, low socioeconomic status and poor performance status. The problems in studying survival from cancer in developing countries and the strategies used to improve follow-up rates in India are discussed. It is stressed that trends in survival rates may be used to evaluate cancer control programmes in developing countries in the absence of reliable mortality statistics and, even when mortality data are available, survival rates are valuable comparative statistics. Earlier detection by improving the awareness of the population and the physicians will improve survival rates, but a more effective and prudent approach would be to prevent invasive cervical cancer, and thereby reduce mortality, by implementing feasible and effective screening programmes in India.
Asian Pacific Journal of Cancer Prevention
Background: Cervical cancer (CC) is the third most common cancer in women globally, including Thailand, where the incidence rate was 16.2 cases per 100,000 individuals in 2018. Survival rates for patients with this condition have not improved over recent years. This study evaluated the survival rate and median survival time after diagnosis among CC patients, and investigated factors associated with survival in Northeast Thailand. Methods: This study included CC patients admitted to the gynecological ward at
Iranian journal of public health, 2013
Cervical cancer is the third most common cancer among women in Malaysia. The objective of this study was to estimate the effect of explanatory variables on survival time of cervical cancer patients receiving treatment at a hospital in Malaysia. In this retrospective record review study, cervical cancer data obtained from Hospital UniversitiSains Malaysia (HUSM) was analysed. The data comprises of 120 patients who had been diagnosed as cervical cancer between 1(st) July 1995 and 30(th) June 2007, and obtained treatment from the hospital. The outcome variable was survival time (in months) from cervical cancer diagnosis to death. A stratified Weibull model was applied to study the effect of explanatory variable on survival time when there was time-dependent covariate in the model. Stage of disease and metastases were important prognostic variables. However, metastasis had been stratified because this variable did not satisfy the proportional hazard assumption. In without metastasis str...