Quinidine as a probe for CYP3A4 activity: Intrasubject variability and lack of correlation with probe-based assays for CYP1A2, CYP2C9, CYP2C19, and CYP2D6
Kim Brøsen
2000
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Inhibition of debrisoquine hydroxylation with quinidine in subjects with three or more functional CYP2D6 genes
L. Bertilsson
British Journal of Clinical Pharmacology, 2002
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Metabolic ratios of four probes of CYP2D6 in Turkish subjects: A cross-over study
Atilla Bozkurt
European Journal of Drug Metabolism and Pharmacokinetics, 1996
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Influence of CYP2D6-dependent metabolism on the steady-state pharmacokinetics and pharmacodynamics of metoprolol and nicardipine, alone and in combination
Jean-Marie Poirier
British Journal of Clinical Pharmacology, 1993
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Effects of cytochrome P450 (CYP) inducers and inhibitors on ondansetron pharmacokinetics in rats: involvement of hepatic CYP2D subfamily and 3A1/2 in ondansetron metabolism
Sihyung Yang
Journal of Pharmacy and Pharmacology, 2008
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Effect of sodium ozagrel on the activity of rat CYP2D6
Wei Yang
European Journal of Pharmacology, 2007
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Expression and localization of CYP1A2, CYP2D1 and CYP3A1 in rat liver and CYP2D4 in rat brain after neuroleptic treatment
Piotr Czekaj
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Inhibitory Effects of Ketoconazole, Cimetidine and Erythromycin on Hepatic CYP3A Activities in Cats
sYed sHer
Journal of Veterinary Medical Science, 2009
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The contribution of the enzymes CYP2D6 and CYP2C19 in the demethylation of artemether in healthy subjects
Trần gỗ cổ điển
European Journal of Drug Metabolism and Pharmacokinetics, 1998
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The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
Stephen Lowe
Drug Metabolism and Disposition, 2012
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Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug
Stephan Krähenbühl
Frontiers in pharmacology, 2018
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Influence of Some Novel N-Substituted Azoles and Pyridines on Rat Hepatic CYP3A Activity
kenneth bachmann
Biochemical Pharmacology, 1998
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Inhibition of Human Cytochrome P450 Enzymes by 1,2-Dithiole-3-thione, Oltipraz and Its Derivatives, and Sulforaphane
André Guillouzo
Chemical Research in Toxicology, 2000
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The 1β-Hydroxy-Deoxycholic Acid to Deoxycholic Acid Urinary Metabolic Ratio: Toward a Phenotyping of CYP3A Using an Endogenous Marker?
Youssef Daali
Journal of Personalized Medicine
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Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinine
Robert Walker
British Journal of Clinical Pharmacology, 2003
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A rapid and simple LC–MS/MS method for the simultaneous evaluation of CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 hydroxylation capacity
Fernando De Andres
Bioanalysis, 2014
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A Comparative Pharmacokinetic Study in Healthy Volunteers of the Effect of Carbamazepine and Oxcarbazepine on Cyp3a4
Per Damkier
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Simultaneous determination of omeprazole, hydroxyomeprazole and omeprazole sulphone in human plasma by isocratic HPLC-DAD: application to the phenotyping of CYP2C19 and CYP3A4 in brazilian volunteers
Andre Arigony
Journal of the Brazilian Chemical Society, 2007
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Effect of diphenoxylate on CYP450 isoforms activity in rats
zezheng liu
International journal of clinical and experimental medicine, 2015
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Phenotype of CYP2C19 and CYP3A4 by determination of omeprazole and its two main metabolites in plasma using liquid chromatography with liquid–liquid extraction
Carlos Hoyo
Journal of Chromatography B, 2002
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Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug–Drug Interaction in Healthy Volunteers
Collen Masimirembwa
Journal of Personalized Medicine, 2021
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Influence ofCYP2D6*10on the pharmacokinetics of metoprolol in healthy Korean volunteers
ss bang
Journal of Clinical Pharmacy and Therapeutics, 2008
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A proposed simple screening method to determine relative contributions of CYP3A4 and CYP3A5 to drug metabolism in vitro
Su Nwe San
Personalized Medicine Universe, 2019
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Enantioselectivity In the Steady-State Pharmacokinetics of Metoprolol In Hypertensive Patients
Paulo Gonçalves
Chirality, 1999
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Induction of CYP2A5 by pyrazole and its derivatives in mouse primary hepatocytes
Markku Pasanen
Archives of Toxicology, 1998
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UPLC-MS-MS Method for Simultaneous Determination of Caffeine, Tolbutamide, Metoprolol, and Dapsone in Rat Plasma and its Application to Cytochrome P450 Activity Study in Rats
Yanshen Li
Journal of Chromatographic Science, 2012
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CYP2C19- and CYP3A4-Dependent Omeprazole Metabolism in West Mexicans
Héctor González
The Journal of Clinical Pharmacology, 2003
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Cytochrome P-450 ω-hydroxylase: a potential O2 sensor in rat arterioles and skeletal muscle cells
Richard Roman
American Journal of Physiology-Heart and Circulatory Physiology
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Drug-drug interactions: Effect of quinidine on nifedipine binding to human cytochrome P450 3A4
Fred Friedman, Aditya Koley
Biochemical Pharmacology, 1997
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Effects of terfenadine and diphenhydramine on the CYP2D6 activity in healthy volunteers
Selim Kortunay
European Journal of Drug Metabolism and Pharmacokinetics, 2002
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Comparative Metabolic Capabilities and Inhibitory Profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17
Hongwu Shen
Drug Metabolism and Disposition, 2007
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Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: Effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA
Poonam Giri
Xenobiotica; the fate of foreign compounds in biological systems, 2016
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Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced mutagenicity
Maria Konstandi
Archives of Toxicology, 2009
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Stereoselective effects of the enantiomers, quinidine and quinine, on depolarization- and agonist-mediated responses in rat isolated aorta
Francisco Zaragoza
British Journal of Pharmacology, 1996
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Enantioselective capillary electrophoresis for the assessment of CYP3A4-mediated ketamine demethylation and inhibition in vitro
Wolfgang Thormann
ELECTROPHORESIS, 2011
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