Corrigendum to “Hysteroscopic versus cervical injection for sentinel node detection in endometrial cancer: A multicenter prospective randomised controlled trial from the Multicenter Italian Trials in Ovarian cancer (MITO) study group” [European Journal of Cancer. Volume 140, November 2020, Pages ... (original) (raw)

2021, European Journal of Cancer

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Usefulness and Limitation of Thyroglobulin Measurement in Fine Needle Aspirates (FNA-Tg) for Diagnosis of Neck Lymph Node Metastasis from Thyroid Carcinoma

Nippon Jibiinkoka Gakkai Kaiho, 2016

Background : Preoperative diagnosis of lymph node metastasis from thyroid carcinoma is usually confirmed by using fine needle aspiration cytology FNAC when thyroid carcinoma is suspected based on the clinical findings. However, the result of FNAC sometimes leads to a false negative, especially in cases of hypocellular lesions such as metastases with cystic change. Thyroglobulin measurement in fine needle aspirates FNA Tg has been shown to be a useful technique to detect the protein specifically secreted by thyroid follicular cells. Elevated FNA Tg levels in an extra thyroidal lesion means that the lesion comprises thyroid originated tissue, most of which suggests the metastasis from thyroid carcinoma. Thus, FNA Tg is expected to improve the sensitivity of FNAC for the aforementioned purpose.

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