The Usefulness of Dermoscopy in Extraocular Sebaceous Carcinoma (original) (raw)
Related papers
Extraocular sebaceous carcinoma: a series of three cases with varied presentation
Dermatology Practical & Conceptual, 2012
Background: Extraocular sebaceous carcinomas are rare cutaneous malignancies that account for only about 25% of all sebaceous carcinomas. The most common site of occurrence is the head/neck region. They are aggressive neoplasms that possess metastatic potential to regional or distant sites. Wide local excision of the lesion with removal of regional lymph nodes is the usual mode of therapy. Methods: We present a series of three cases of sebaceous carcinomas occurring in extraocular sites outside the head and neck areas, like the axilla, chest wall, arm and thigh. One of these cases had an associated colonic carcinoma and constituted Muir-Torre syndrome (MTS). Another case presented with a skin nodule and regional nodal metastasis. The third case had a history of recurrent similar lesions at the same site. Conclusion: Although rare, extraocular sebaceous carcinomas are seen at varied sites and frequently pose problems in diagnosis. A longterm follow-up of these cases is warranted due to their aggressive behaviour, risks of recurrence, metastasis and the possibility of development of visceral malignancies.
Dermoscopy of the Month Dermoscopic Features of Sebaceous Nevus - a Report of 4 Cases
Serbian Journal of Dermatology and Venereology, 2018
Sebaceous nevus is a congenital hamartoma commonly associated with the development of secondary neoplasms. It has a predilection for the scalp and less commonly manifests on the face, the neck, and the trunk. The lesions presented in our cases are from the trunk of a 19-year old man, the forehead of a 25-year old man, the scalp of a 22-year old woman and from the face of a 45-year old man. Two of four cases were associated with secondary neoplasms, syringoma and basal cell carcinoma. Dermoscopy of nevus sebaceous demonstrated yellowish-brown globular structures, presenting either singly or in clusters and pink-brown-grey papillary appearance. The specific dermoscopic findings in our case associated with basal cell carcinoma were fine arborizing and serpiginous vessels at the periphery of the lesion and exophytic grey papillary structures. Dermoscopy can be a useful diagnostic tool for diagnosing and monitoring nevus sebaceous in order to detect different tumors associated with nevus...
Extra-Ocular Sebaceous Carcinoma of the Skin: A Report of Five Cases and a Review of the Literature
American Journal of Medical Case Reports, 2015
Background: Extra ocular sebaceous carcinoma is a rare aggressive adnexal tumour. The diagnosis of this tumour is difficult due to the variety of its clinical and histopathological features. The prognosis is actually considered as aggressive as the ocular counterpart. Methods and results: We propose to discuss the clinical features, histopathological findings and aggressive potential of extra ocular sebaceous carcinoma. Therefore, five extra ocular sebaceous carcinoma cases, diagnosed at the Dermatology and Pathology departments of Farhat Hached Hospital, from January 1998 to December 2007, were reviewed. The diagnosis was based on a histopathological examination. Three of them developed locoregional and/or distant metastases. One patient died from metastatic disease. Surgery was the mainstay of treatment without any cutaneous recurrence after a mean follow-up of two years. Conclusions: Extra ocular sebaceous carcinoma has an unpredictable prognosis. It can be highly aggressive and ...
Should Extraocular Sebaceous Carcinoma Be Investigated Using Sentinel Node Biospy?
Dermatologic Surgery, 2009
A 61-year-old man presented to his general practitioner (GP) with a 6-month history of an asymptomatic cutaneous lesion to the upper left side-wall of his nose. He was otherwise well and was taking no medication. Physical examination demonstrated a 5-Â 5-mm firm red cystic lesion. There was no evidence of regional metastases.
Extraocular sebaceous carcinoma of neck: A case Report
Context: Sebaceous cell carcinoma is a malignant neoplasm, rarely recognized in extra ocular sites. This neoplasm is aggressive in 29% of patients, lymph node and visceral metastasis are common. Its prognosis depends on early diagnosis of lesion. Clinical &Diagnostic features: An 49 year old female had slow growing nonulcerative subcutaneous nodule on the nape of neck of 9 months duration. On FNAC cytological findings favoured a benign skin adenexal tumor with focal nuclear atypia. On histological examination it was diagnosed as a poorly differentiated sebaceous carcinoma. Conclusion: Extra ocular sebaceous carcinoma is a rare neoplasm. It is difficult to diagnose as it has diverse clinical presentations, histologic patterns and complicated nomenclature. We will discuss the incidence, clinical, and histological findings along with the prognosis of this aggressive neoplasm.
Sebaceous carcinoma of the eyelid: anatomoclinical data
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2013
Sebaceous gland carcinoma of the eyelid is a rare slow-growing tumor and is one of the most aggressive malignancies of the eyelid. Diagnosis is often delayed because it can be confused with other periocular lesions. We report the case of a 78-year-old female who presented for the anesthetic aspect of a nodular tumor on the right upper eyelid occurring one year earlier. The patient was treated for three months for recurrent chalazion. Ophthalmologic examination revealed a nodular ulcerated tumor of 1 cm in size adherent to adjacent tissues. Surgical excision was performed with a safety margin of 4 mm. The diagnosis of moderately differentiated sebaceous carcinoma was made by routine morphological methods and immunohistochemical reactions (EMA and Ki-67). Being a rare tumor with considerable morbidity and mortality, early diagnosis and proper treatment are essential for a favorable prognosis and preservation of visual function.
Journal of Maxillofacial and Oral Surgery, 2013
Purpose Sebaceous carcinoma (SC) is a rare adnexal tumor. Extra-ocular, facial SC is very uncommon and local metastases are an extreme rare finding. A respective case is presented and discussed together with the current literature. Case and Review A tumor of the left ear of an 87-old male was primary excised together with multiple suspicious lesions of the head and neck. Most specimens were histopathologically rated as squamous cell carcinomas (SCC). Despite the in-sano resection, additional new suspicious retro-auricular and temporal lesions were detected. Successive resections were diagnosed as basal cell carcinomas (BCC) and, because of a non-in-sano resection in a third approach, as SC. After reappraisal and immunhistochemical staining [epithelial membrane antigen (EMA), CK 5-6 and CD 15], most of the former specimens turned out to be SC as well. A literature search showed 3 reported cases of extra-ocular head and neck SC with cutaneous local metastases. In another review, in a total of 168 cases, SC was diagnosed after wrong initial histological diagnosis (SCC n = 56, BCC n = 44; other entity or precursors of carcinomas n = 68).
Sebaceous carcinoma in situ as a diagnostic entity. Case report and review of the literature
Albanian Journal of Trauma and Emergency Surgery
The concept of carcinoma in situ was first introduced by Broders in 1932 [1] and has been accepted as a well-established notion and diagnostic category in many organs and systems. However, sebaceous carcinoma in situ (SCIS) has not yet been recognized as a concept and diagnostic entity in general pathology or dermatopathology. Such lesions have been commonly misinterpreted as either a benign neoplasm or sebaceous carcinoma. Tumors that do not necessarily arise in pre-existing sebaceous glands are usually invasive at the time of diagnosis, and like their ocular counterparts, can exhibit pagetoid intraepidermal spread. Cases of purely in- situ extraocular sebaceous carcinoma are extremely rare and yet controversial until now.Recognizing sebaceous carcinoma in situ as a valid concept and diagnostic entity that will certainly help to avoid misinterpretation and subsequently under or over treatment of such lesions.In this article, we provide a case report presentation with histopathologi...
Differentiating basal cell carcinoma from intradermal nevi on the eyelid: The utility of dermoscopy
International Journal of Women's Dermatology, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.