The GTPase switch in ribosomal translocation (original) (raw)

Coupling of GTP Hydrolysis by Elongation Factor G to Translocation and Factor Recycling on the Ribosome †

Biochemistry, 2002

Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome

Proceedings of the National Academy of Sciences, 2006

Dual use of GTP hydrolysis by elongation factor G on the ribosome

Translation, 2013

Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation

Norbert Polacek

Nature Chemical Biology, 2010

The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form

Vladimir Mitkevich

Proceedings of the National Academy of Sciences, 2008

Conformationally Restricted Elongation Factor G Retains GTPase Activity but Is Inactive in Translocation on the Ribosome

Molecular Cell, 2000

Structure of the ribosome with elongation factor G trapped in the pretranslocation state

Axel Brilot

Proceedings of the National Academy of Sciences, 2013

Ribosome-induced tuning of GTP hydrolysis by a translational GTPase

Cristina Maracci

Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis

BioEssays : news and reviews in molecular, cellular and developmental biology, 2014

GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits

The EMBO journal, 2014

Stimulation of the GTPase Activity of Translation Elongation Factor G by Ribosomal Protein L7/12

Journal of Biological Chemistry, 2000

EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome

Rajendra Agrawal

Nature structural biology, 1999

Comment on “The Mechanism for Activation of GTP Hydrolysis on the Ribosome”

Anders Liljas

Science, 2011

Control of phosphate release from elongation factor G by ribosomal protein L7/12

The EMBO Journal, 2005

An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation

Molecular cell, 2003

Formation of a functional ribosome-membrane junction during translocation requires the participation of a GTP-binding protein

Reid Gilmore

The Journal of Cell Biology, 1986

Large-Scale Movement of Elongation Factor G and Extensive Conformational Change of the Ribosome during Translocation

Cell, 2000

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

Maria Selmer

Science, 2009

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

Måns Ehrenberg

Journal of biology, 2005

Nature Structural & Molecular Biology, 2010

Elongation factor Tu.ribosome dependent GTP hydrolysis: elucidation of the role of the AA-tRNA 3' terminus and site(s) involved in the inducing of the GTPase reaction

Gyanendra Kumar

Biochemistry, 1982

tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis

Cell Reports, 2018

GTPases and the origin of the ribosome

Hyman Hartman

Biology Direct, 2010

[Mechanism of tRNA translocation on the ribosome]

Molekuliarnaia biologiia

Translocation by the Eukaryotic 80 S Ribosome and the Impact of GTP Hydrolysis Graphical

2018

Alteration in Location of a Conserved GTPase-associated Center of the Ribosome Induced by Mutagenesis Influences the Structure of Peptidyltransferase Center and Activity of Elongation Factor G

Alexey Bogdanov

Journal of Biological Chemistry, 2005

Structural basis of early translocation events on the ribosome

Nature, 2021

The elongation factor G carries a catalytic site for GTP hydrolysis, which is revealed by using 2-propanol in the absence of ribosomes

Mariorosario Masullo

Journal of Biological Chemistry

Dynamics of translation on the ribosome: molecular mechanics of translocation

FEMS Microbiology Reviews, 1999

Translocation in ribosomes by attachment—detachment of elongation factor G without GTP cleavage: Evidence from a column-bound ribosome system

Marina Glukhova, Alexander Spirin

FEBS Letters, 1975

The Stoichiometry of Ribosomal Translocation

David Contreras Vazquez

Journal of Biological Chemistry, 1973

Control of Ribosomal Subunit Rotation by Elongation Factor G

Arto Pulk

Science, 2013

EF-G-Dependent GTPase on the Ribosome. Conformational Change and Fusidic Acid Inhibition †

Knud Nierhaus

Biochemistry, 2006

Role of Domains 4 and 5 in Elongation Factor G Functions on the Ribosome

Journal of Molecular Biology, 2000