Uses and limitations of IgG4 positive plasma cells in evaluating ulcerative colitis (original) (raw)

Abstract

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Uses and limitations of IgG4 positive plasma cells in evaluating ulcerative colitis were examined. IgG4 positive cells were studied as potential biomarkers for assessing disease states and their implications in treatment strategies. However, the findings revealed that the presence of IgG4 positive cells might not be a reliable indicator for the evaluation and management of ulcerative colitis, highlighting the need for further research to explore more definitive diagnostic tools.

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References (28)

  1. American Gastroentrological Association medical position statement: guidelines on the use of esophageal pH recording. Gastroenterology 1996;110:1981-1996. doi:10.1053/gast.1996.1101981
  2. Pehl C, Boccali I, Henning M, Schepp W. pH probe positioning for 24-hour pH-metry by manometry or pH step-up. Eur J Gastroenterol Hepatol 2004;16:375-382.
  3. Can MF, Yagci G, Cetiner S, et al. Accurate positioning of the 24-hour pH monitoring catheter: Agreement between manometry and pH step-up method in two patient positions. World J Gasteroenterol 2007;13:6197- 6202.
  4. Nasi A, Frare Rde C, Brandao JF, Falcao AM, Muchelsohn NH, Sifrim D. Comparative prospective study of two positioning modes of 24-hour esophageal pH monitoring: by esophageal manometry and by the pH step-up technique. Arq Gastroenterol 2008;45:261-267. doi:10.1590/ S0004-28032008000400002
  5. Mattox HE, Richter JE, Sinclair JW, Price JE, Case LD. Gastroesophageal pH step-up inaccurately locates proximal border of lower esophageal sphincter. Dig Dis Sci 1992;37:1185-1191. doi:10.1007/BF01296558
  6. Zaharie F, Mocan L, Mocan T, et al. Surgical management of malignant large bowel obstructions. Chirurgia (Bucur) 2011;106:479-484.
  7. Iancu C, Osian G, Mocan L, et al. Management of colorectal resections for treatment of neoplastic intestinal occlusions. Experience of surgery clinic No III, Cluj-Napoca. Chirurgia (Bucur) 2008;103:45-51.
  8. Halabi WJ, Kang CY, Ketana N, et al. Surgery for gallstone ileus: a nationwide comparison of trends and outcomes. Ann Surg 2014;259:329-335. doi:10.1097/SLA.0b013e31827eefed
  9. Puia IC, Puia VR, Andreescu A, Cristea PG. Ascending colon perforation by ingested fruit stones. Chirurgia (Bucur) 2011;106:825-827.
  10. Clavien PA, Richon J, Burgan S, Rohner A. Gallstone ileus. Br J Surg 1990;77:737-742. doi:10.1002/bjs.1800770707
  11. Nuño-Guzmán CM, Marín-Contreras María Eugenia, Figueroa- Sánchez M, Corona JL. Gallstone ileus, clinical presentation, diagnostic and treatment approach. World J Gastrointest Surg 2016;8:65-76. doi:10.4240/wjgs.v8.i1.65
  12. Yu CY, Lin CC, Shyu RY, et al. Value of CT in the diagnosis and management of gallstone ileus. World J Gastroenterol 2005;11:2142- 2147. doi:10.3748/wjg.v11.i14.2142
  13. Nakao A, Okamoto Y, Sunami M, Fujita T, Tsuji T. The oldest patient with gallstone ileus: report of a case and review of 176 cases in Japan. Kurume Med J 2008;55:29-33. doi:10.2739/kurumemedj.55.29 REFERENCES
  14. Radoi VE, Ursu RI, Poenaru E, Arsene C, Bohiltea CL, Bohiltea R. Frequency of the UGT1A1*28 Polymorphism in a Romanian Cohort of Gilbert Syndrome Individuals. J Gastrointestin Liver Dis 2017;26:25-28. doi:10.15403/jgld.2014.1121.261.ugt
  15. Beutler E, Gelbart T, Demina A. Racial variability in the UDP- glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? Proc Natl Acad Sci U S A 1998;95:8170-8174.
  16. Guillemette C, De Vivo I, Hankinson SE, et al. Association of genetic polymorphisms in UGT1A1 with breast cancer and plasma hormone levels. Cancer Epidemiol Biomarkers Prev 2001;10:711-714.
  17. Guillemette C, Millikan RC, Newman B, Housman DE. Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans. Cancer Res 2000;60:950-956.
  18. Rawa K, Adamowicz-Salach A, Matysiak M, Trzemecka A, Burzynska B. Coexistence of Gilbert syndrome with hereditary haemolytic anaemias. J Clin Pathol 2012;65:663-665. doi:10.1136/jclinpath-2011-200580
  19. Nikolac N, Simundic AM, Topic E, et al. Rare TA repeats in promoter TATA box of the UDP glucuronosyltranferase (UGT1A1) gene in Croatian subjects. Clin Chem Lab Med 2008;46:174-178. doi:10.1515/ CCLM.2008.035
  20. Ekblom K, Marklund SL, Johansson L, et al. Bilirubin and UGT1A1*28 are not associated with lower risk for ischemic stroke in a prospective nested case- referent setting. Cerebrovasc Dis 2010;30:590-596. doi:10.1159/000319778
  21. Ekblom K, Marklund SL, Jansson JH, et al. Plasma bilirubin and UGT1A1*28 are not protective factors against first-time myocardial infarction in a prospective, nested case-referent setting. Circ Cardiovasc Genet 2010;3:340-347. doi:10.1161/CIRCGENETICS.109.861773
  22. Kian Keyashian 1* , Eleonora Duregon 2* , Brian T. Brinkerhoff 3,5 , Laura Bradley 1,6 , Benjamin Larson 1,7 , Jeong Lim 4 , Nir Modiano 1 , Judy Collins 1 , Terry K. Morgan 3 , Jody E. Hooper 2 (*equally contributed to the study)
  23. Department of Internal Medicine, Division of Gastroenterology, Oregon Health & Science University, Portland, Oregon; 2) Department of Pathology, The Johns Hopkins University, Baltimore, Maryland; 3) Department of Pathology, OHSU, Portland, Oregon; 4) Biostatistics and Design Program, School of Public Health, OHSU, Portland, Oregon; 5) Chinook Regional Hospital, Alberta Health Services, Alberta; 6) Department of Internal Medicine, University of California, Davis, California; 7) Department of Internal Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Correspondence: Jody E. Hooper, jhooper9@jhmi.edu REFERENCES
  24. Patil DT, Moss AC, Odze RD. Role of histologic inflammation in the natural history of ulcerative colitis. Gastrointest Endosc Clin N Am 2016;26:629-640. doi:10.1016/j.giec.2016.06.009
  25. Ravi K, Chari ST, Vege SS, Sandborn WJ, Smyrk TC, Loftus EV Jr. Inflammatory bowel disease in the setting of autoimmune pancreatitis. Inflamm Bowel Dis 2009;15:1326-1330. doi:10.1002/ibd.20898
  26. Navaneethan U, Venkatesh PG, Choudhary M, Shen B, Kiran RP. Elevated immunoglobulin G4 level is associated with reduced colectomy-free survival in patients with primary sclerosing cholangitis and ulcerative colitis. J Crohns Colitis 2013;7:e35-e41. doi:10.1016/j. crohns.2012.04.006
  27. Şimşek HD, Basyigit S, Aktas B, et al. Comparing the type and severity of inflammatory bowel disease in relation to IgG4 immunohistochemical staining. Acta Gastroenterol Belg 2016;79:216- 221.
  28. Kuwata G, Kamisawa T, Koizumi K, et al. Ulcerative colitis and immunoglobulin G4. Gut Liver 2014;8:29-34. doi:10.5009/ gnl.2014.8.1.29