Preclinical and clinical evidence of nephro- and cardiovascular protective effects of glycosaminoglycans (original) (raw)

Nephroprotective action of glycosaminoglycans: why the pharmacological properties of sulodexide might be reconsidered

Arrigo Cicero

International journal of nephrology and renovascular disease, 2010

View PDFchevron_right

Glycosaminoglycans prevent morphological renal alterations and albuminuria in diabetic rats

Giovanni Gambaro

Kidney International, 1992

View PDFchevron_right

Treatment with a glycosaminoglycan formulation ameliorates experimental diabetic nephropathy

Giovanni Gambaro

Kidney International, 1994

View PDFchevron_right

The Role of Sulodexide in the Treatment of Diabetic Nephropathy

Robert Niecestro

Drugs, 2007

View PDFchevron_right

Glycosaminoglycans, proteoglycans and sulodexide and the endothelium: biological roles and pharmacological effects

Giovanni Gambaro

International angiology : a journal of the International Union of Angiology, 2014

View PDFchevron_right

Sulodexide Fails to Demonstrate Renoprotection in Overt Type 2 Diabetic Nephropathy

David Packham

Journal of the American Society of Nephrology, 2012

View PDFchevron_right

The Heparanase Inhibitor (Sulodexide) Decreases Urine Glycosaminoglycan Excretion and Mitigates Functional and Histological Renal Damages in Diabetic Rats

jamal khalilpour

Acta Medica Bulgarica, 2019

View PDFchevron_right

Efficacy of low-dose oral sulodexide in the management of diabetic nephropathy

Ben Baya Brahim

Journal of nephrology

View PDFchevron_right

Renal Effects of Sulodexide in Type 2 Diabetic Patients without Nephrotic Range Proteinuria

Bancha Satirapoj

Journal of Diabetes Research, 2020

View PDFchevron_right

The effects of the therapy with natural glycosaminoglycans (Sulodexide) on proteinuria in different types of glomerulonephritis

Ligia Petrica

Facta Universitatis, …, 2001

View PDFchevron_right

Sulfated glycosaminoglycans restore glycocalyx barrier properties of cultured endothelial cells in hyperglycemia

Lysette Broekhuizen

The FASEB Journal, 2008

View PDFchevron_right

Urinary excretion of glycosaminoglycans and albumin in experimental diabetes mellitus

Y. Michelacci

Glycobiology, 2000

View PDFchevron_right

The Protective Role of Fucosylated Chondroitin Sulfate, a Distinct Glycosaminoglycan, in a Murine Model of Streptozotocin-Induced Diabetic Nephropathy

Christina Takiya

PLoS ONE, 2014

View PDFchevron_right

Oral Sulodexide Reduces Albuminuria in Microalbuminuric and Macroalbuminuric Type 1 and Type 2 Diabetic Patients

Domenico Fedele

Journal of the American Society of Nephrology, 2002

View PDFchevron_right

Glycosaminoglycans urinary excretion as a marker of the early stages of diabetic nephropathy and the disease progression

Maria Gorska

Diabetes/Metabolism Research and Reviews, 2008

View PDFchevron_right

Effect of Sulodexide on Urinary Biomarkers of Kidney Injury in Normoalbuminuric Type 2 Diabetes: A Randomized Controlled Trial

Prajej Ruangkanchanasetr

Journal of Diabetes Research, 2015

View PDFchevron_right

No Change in Glomerular Heparan Sulfate Structure in Early Human and Experimental Diabetic Nephropathy

Jo Berden

Journal of Biological Chemistry, 2006

View PDFchevron_right

Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus

Lysette Broekhuizen

Diabetologia, 2010

View PDFchevron_right

Glycosaminoglycans and fucoidan have a protective effect on experimental glomerulonephritis

Tom Nijenhuis

Frontiers in Molecular Biosciences, 2023

View PDFchevron_right

Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial

Robert Atkins

American Journal of Kidney Diseases, 2011

View PDFchevron_right

Efficacy of long-term low-dose sulodexide in diabetic and non-diabetic nephropathies

Diana Zilisteanu

Romanian Journal Of Internal Medicine, 2015

View PDFchevron_right

Glycosaminoglycan treatment in glomerulonephritis? An interesting option to investigate

Norella Kong

Journal of nephrology

View PDFchevron_right

Regulation of Glomerular Endothelial Cell Proteoglycans by Glucose

Tae-sun Ha

Journal of Korean Medical Science, 2004

View PDFchevron_right

A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition

Giovanni Gambaro

Journal of Translational Medicine, 2012

View PDFchevron_right

Glycosyl albumin and diabetic microalbuminuria: Demonstration of an altered renal handling

Giovanni Candiano

Kidney International, 1984

View PDFchevron_right

Rationale for and study design of the sulodexide trials in Type 2 diabetic, hypertensive patients with microalbuminuria or overt nephropathy

David Packham

Diabetic Medicine, 2007

View PDFchevron_right