Chemical profiling and free radical scavenging potential of Oxalis corniculata (original) (raw)

2016

Abstract

The present work was carried out to evaluate the free radical scavenging potential of Oxalis coriculata. The ethanol (80%) extract was tested for free radical scavenging assay using DPPH, Nitric oxide and ABTS assay. Furthermore, qualitative along with quantitative estimation of flavonoids and phenolic contents were also carried out using aluminium chloride and Folin–Ciocalteu reagent method respectively. Preliminary phytochemical screening of the extract revealed the presence of various bioactive compounds such as steroids, phenolic groups, saponins, tannin, flavonoids, carbohydrates, coumarins, alkaloids and terpenoids. The total phenolic and flavonoid contents were found to be 2.11± 0.08 mg/100mg dry weight equivalents to gallic acid (GAE)/ 100mg dry weight and 4.45±0.15 mg/100mg dry weight equivalents to quercetin (QE), respectively. The extract revealed significant antiradical activity in a dose-dependent manner in all the assays. The IC 50 values of all parameters were also determined using ascorbic acid as a standard. HPLC analysis further confirmed the presence of rutin, salicylic acid and benzoic acid. The results obtained in the present work indicated that O. corniculata could be a potential source of natural antioxidant.

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