Ischemic Stroke Profile, Risk Factors, and Outcomes in India: The Indo-US Collaborative Stroke Project (original) (raw)
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Introduction: Acute ischemic stroke, a subtype of acute stroke is one of the leading causes of death and major cause of morbidity and mortality throughout the world. The incidence of acute ischemic stroke is increasing with gradual increase in obesity, diabetes mellitus, hyperlipidemia, hypertension and some other cardiac problem. Objective: The study has been conducted with a primary objective to study the epidemiology and clinical presentation of acute ischemic stroke. Methods: This cross sectional study was carried out among 100 acute ischemic stroke patients(clinically and radiologically confirmed) irrespective of age and sex admitted to Medicine and Emergency Department of Regional Institute of Medical Sciences(RIMS), Imphal after getting clearance from Institutional Ethical Committee(IEC). The acute ischemic stroke patients were also undergone plane CT (computed tomography) scan brain by the CT scan model Philips Brilliance 64 slice CT for radiological confirmation and to localize the lesion in brain. Data, collected in prescribed protocol, were analyzed in simple statistical percentage. Result: Acute ischemic stroke was found most commonly in 50-75 age group with male predominance. Majority of the acute stroke patients were smoker, non-vegetarian and hypertensive. The commonest clinical feature at presentation was hemiplegia. Rightsided hemiplegia was the predominant finding in acute stroke patients. Left hemisphere brain infarction was more common than right hemisphere lesion in brain. Conclusion: In this study, the epidemiology, clinical presentation and various risk factors of acute ischemic stroke have been focused, by targeting which the burden of this disabling disease can be prevented.
Introduction: Acute ischemic stroke, a subtype of acute stroke is one of the leading causes of death and major cause of morbidity and mortality throughout the world. The incidence of acute ischemic stroke is increasing with gradual increase in obesity, diabetes mellitus, hyperlipidemia, hypertension and some other cardiac problem. Objective: The study has been conducted with a primary objective to study the epidemiology and clinical presentation of acute ischemic stroke. Methods: This cross sectional study was carried out among 100 acute ischemic stroke patients(clinically and radiologically confirmed) irrespective of age and sex admitted to Medicine and Emergency Department of Regional Institute of Medical Sciences(RIMS), Imphal after getting clearance from Institutional Ethical Committee(IEC). The acute ischemic stroke patients were also undergone plane CT (computed tomography) scan brain by the CT scan model Philips Brilliance 64 slice CT for radiological confirmation and to localize the lesion in brain. Data, collected in prescribed protocol, were analyzed in simple statistical percentage. Result: Acute ischemic stroke was found most commonly in 50-75 age group with male predominance. Majority of the acute stroke patients were smoker, non-vegetarian and hypertensive. The commonest clinical feature at presentation was hemiplegia. Rightsided hemiplegia was the predominant finding in acute stroke patients. Left hemisphere brain infarction was more common than right hemisphere lesion in brain. Conclusion: In this study, the epidemiology, clinical presentation and various risk factors of acute ischemic stroke have been focused, by targeting which the burden of this disabling disease can be prevented.
Risk Factors for Stroke: A Hospital Based Descriptive Study in North India
International Journal of Stroke Research, 2015
Introduction: Stroke is a major public health problem, both in developed and developing world. It causes a lot of morbidity and mortality especially with advancing age and lot of economic burden on the families of those afflicted with stroke. Aim: To find out the association of risk factors like Obesity, Cholesterol, Smoking and Alcohol to the Stroke. Methodology: The present descriptive study was conducted in the calendar year of 2011. The study subjects comprised of the patients who were admitted to Govt. Medical College and Hospital Jammu with sign and symptoms suggestive of stroke. The relevant information of each study subject was recorded on pre-designed and pre-tested proforma. Results: A total of 209 respondents (114 males and 95 females) were interviewed during the course of study. 57.90% (121/209) study subjects were found to be obese. 77.96% (92/118) had cholesterol level on the higher side. Out of 114 males in the current study 60.52% (69/114) were smoker and 62.28% (71/114) were alcoholic. Both smoking and alcohol were found to be statistically significant risk factors for stroke. Conclusions: The results clearly demonstrate that lifestyle factors have a huge impact on the causation of non-communicable diseases in general and stroke in particular and hence the need for primordial prevention at the earliest.
International Journal Of Community Medicine And Public Health, 2020
Background: Stroke is the second leading cause of mortality and morbidity worldwide. Cardioembolic stroke accounts for 15-30% of Ischemic stroke. There have been very few clinical studies on cardioembolic stroke, especially from India. Our aim was to provide a demographic, risk factor and clinical profile of patients with cardioembolic stroke in South India.Methods: A prospective study was conducted at the Neurology Inpatient Department over a period of 5 years from January 2013 to January 2018 collecting necessary information and data from all cases diagnosed as cardioembolic stroke.Results: 651 patients were diagnosed to have acute Ischemic stroke. Of the 76 patients (11.6%) diagnosed with cardioembolic stroke, 35 (46%) were females. Mean age was 53.5±12.2 years. Occurrence of cardioembolic stroke was seen to be higher (71% vs 28.9%, p value<0.0001) in patients of older age group (46 years or more). A significant proportion of patients of the older age group (37%) had hypertens...
International Journal of Clinical Trials, 2014
Stroke is a devastating and disabling cerebrovascular disease with significant amount of residual deficit leading on to economic loss. It has been defined as a rapidly developing signs of focal (or global) disturbance of cerebral function with symptoms lasting for ≥24 hours, or leading to death with no apparent cause other than vascular origin. 1 It is a collection of clinical syndromes resulting from cerebral ischemia to intracranial hemorrhage. In the west, it is the 3rd most common cause of morbidity and mortality. 2 Some of the recent studies have elucidated the stroke pattern to considerable extent in our country with a prevalence rate o471.58/100000 population. 3 Recent study identified that 7% of medical and 45% of neurological admissions were due to stroke with a fatality rate of 9% at hospital discharge and 20% at 28 days. 4 Hypertension, alcoholism, smoking & dyslipidemia are commonest cause of stroke among the elderly, 5 and smoking, alcoholism, increased BMI, diabetes and hypertension are significantly associated with strokes among young people. 6
IJAM, 2019
INTRODUCTION Worldwide, cerebrovascular accidents (stroke) are the second leading cause of death and the third leading cause of disability. 1 Stroke, the sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is lost by blockage or rupture of an artery to the brain, is also a leading cause of dementia and depression. 2 Globally, 70% of strokes and 87% of both stroke-related deaths and disability-adjusted life years occur in low-and middle-income countries. 3-5 Over the last four decades, the stroke incidence in low-and middle-income countries has more than doubled. During these decades stroke incidence has declined by 42% in high-income countries.3 On average, stroke occurs 15 years earlier in-and causes more deaths of-people living in low-and middle-income countries, when compared to those in high-income countries. 2 Strokes mainly affect individuals ABSTRACT Background: Worldwide, cerebrovascular accidents (stroke) are the second leading cause of death and the third leading cause of disability. According to WHO estimation, by 2050 nearly 80% of stroke cases may occur in low and middle-income countries like China and India. It is critical that we understand the etiology causing the stroke so that appropriate treatment can be initiated in a timely fashion. Furthermore, understanding the risk factors associated with stroke is important before primary and secondary preventive measures can be prescribed to the patient. Methods: This observational study was carried out amongst 481 acute ischemic stroke patients that fulfils the inclusion and exclusion criteria and admitted in medicine ward Results: In our study, 481(60.43%) patients had ischemic stroke and 315 (39.57%) patients had hemorrhagic stroke. The incidence of stroke is maximum in 51-70 years of age group which comprises of 59.46% of total patients. The average age + SD were 61.4±13.1 in our study. The most common risk factor was hypertension with 69.85% followed by dyslipidemia 51.77%. Most common clinical presentation was hemiplegia (72.35%) followed by speech involvement (59.46%). Most common site of infarct was parietal (22.25%), followed by periventricular (12.68%). Conclusions: Most of the patients had ischemic stroke as compared to hemorrhagic stroke. It was more common in males. The study contributes to understanding of demographic characteristics, risk factors, and stroke subtypes in acute ischemic stroke. The importance of various risk factors among ischemic stroke subtypes should be stressed for prompt preventive strategies and treatment.
Clinical and Etiological Profile of Ischemic Stroke in a Tertiary Care Hospital of Nepal
https://www.ijhsr.org/IJHSR\_Vol.12\_Issue.6\_June2022/IJHSR-Abstract.028.html, 2022
Background: Stroke is one of the most common neurological diseases, often leading to disability and death. Ischemic stroke accounts for 80-85% of all stroke cases. This Study aimed to evaluate the clinical and etiological profile of patients of ischemic cerebrovascular stroke. Materials and Methods: This was a cross sectional, observational study of 93 patients of ischemic cerebrovascular stroke, conducted at Bir Hospital, Kathmandu during January 2018 to December 2019. The patients detailed history, examinations, blood investigation, CT Scan head and Echocardiography was done. The data were recorded in Excel a sheet and analyzed by SPSS 20. Results: The mean age of ischemic stroke patients was 63.28 +_ 15.52 with a range from 30 to 94 years. The stroke was predominant in male with 52(55.91 %). The most common risk factors for stroke were hypertension 54(58.06%), followed by smoking 48(51.61%), LVH 45(48.38%), hypercholesterolemia 26(27.95%), diabetes mellitus 11(11.82%), atrial fibrillation 3(3.22%) and coronary artery disease 1(1.07%). Hemiplegia was present in all the patients. Other common symptoms included dysarthria due to facial deviation in 73.11%, speech aphasia in 6.45 % and altered sensorium/loss of consciousness in 1.07 % patients. Conclusion: Stroke is not limited to elderly population; younger adults are also vulnerable for stroke. Hypertension, smoking, hypercholesterolemia, diabetes mellitus are common risk factors which can be modified for prevention of stroke.
Journal of Kathmandu Medical College
Background: Stroke is a disabling condition that has physical and mental impact on a patient’s life. Stroke is an important morbidity for low and middle income countries like Nepal. Hypertension, diabetes, smoking, and dyslipidemia are common risk factors in this regard and are inadequately controlled; mainly because of poor public awareness, inadequate infrastructure, lack of service and qualified manpower.Objectives: This study aims to provide insight into the epidemiology and risk factors in ischemic stroke patients.Methodology: A descriptive cross sectional study was conducted in 92 ischemic stroke patients at a tertiary care hospital Kathmandu Medical College and Teaching Hospital (KMCTH), Sinamangal, Nepal from December 2017 to June 2018. Consecutive sampling technique was used and data was collected from ischemic stroke patients above 14 years of age who were admitted in the Department of Neurology. Information regarding pre-morbid and morbid conditions, imaging findings as w...
The Professional Medical Journal
Objective: To identify the prevalence of modifiable risk factors of ischemic stroke. Study Design: Cross Sectional Study. Setting: Department of Medicine, Bahawal Victoria Hospital, Bahawalpur. Period: July 2019 to December 2019. Material & Methods: Detailed history, clinical examination and CT scan (plain) of brain was performed and data was collected on pre-designed questionnaires. Results: Out of a total of 97 patients, there were 69.1% female and 30.1% male. Majority of the patients, 51.5% were aged more than 60 years. Hypertension was the most prevalent risk factor (56.7%) followed by ischemic heart disease (45.4%), diabetes mellitus (27.8%), dyslipidemia (26.8%) & smoking (34%). Conclusion: Modifiable risk factors of ischemic stroke should be identified in general population so that this disease can be prevented.