1354 Glycemic Variability is an Independent Prognostic Factor for Development of Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease (original) (raw)

Patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) exhibit a range of metabolic disorders, notably insulin resistance and type 2 diabetes. This research identifies glycemic variability, assessed via continuous glucose monitoring and oral glucose tolerance tests, as a significant prognostic factor for the progression of hepatic fibrosis in NAFLD. Findings indicate that as fibrosis advances, insulin levels and glycemic variability notably increase, underscoring their role in disease progression.