Molecular Drug Targets in Candida glabrata (original) (raw)

Molecular investigations on Candida glabrata clinical isolates for pharmacological targeting

Hrishikesh Gupta

RSC Advances

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Ergosterol Biosynthesis Inhibitors Become Fungicidal when Combined with Calcineurin Inhibitors against Candida albicans, Candida glabrata, and Candida krusei

C. Onyewu

Antimicrobial Agents and Chemotherapy, 2003

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Review Pathogenesis and Antifungal Drug Resistance of the Human Fungal Pathogen Candida glabrata

Karl Kuchler

2011

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In Vitro Activities of Six Antifungal Drugs Against Candida glabrata Isolates: An Emerging Pathogen

Tahereh Shokohi

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Pathogenesis and Antifungal Drug Resistance of the Human Fungal Pathogen Candida glabrata

Michael Tscherner

Pharmaceuticals, 2011

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Antifungals: Need to search for a new molecular target

uday deshpande

Indian Journal of Pharmaceutical Sciences, 2008

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Global Clinical Case Studies in Candida species: A Review

Dr. Vijay Karuppiah, Dhandayuthapani Nisha

Asian Journal of Research in Biosciences, 2024

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Glabridin Induces Over-expression of Two Major Apoptotic Genes, MCA1 and NUC1, in Candida albicans

hamed fathi

Journal of global antimicrobial resistance, 2017

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review article antifungal research Strategies aiming for New targets

Frances M Segarra, J. Rodriguez

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Molecular Characterization and In Vitro Antifungal Susceptibility of Candida Glabrata Clinical Isolates with Reduced Echinocandin Susceptibility and High Level Multi-Azole Resistance

Dwayne Baxa

Clinical microbiology, 2014

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Cyclic AMP Signaling Pathway Modulates Susceptibility of Candida Species and Saccharomyces cerevisiae to Antifungal Azoles and Other Sterol Biosynthesis Inhibitors

Pooja Jain

Antimicrobial Agents and Chemotherapy, 2003

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Candida glabrata Drug:H + Antiporter CgQdr2 Confers Imidazole Drug Resistance, Being Activated by Transcription Factor CgPdr1

Hiroji Chibana

Antimicrobial Agents and Chemotherapy, 2013

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Genomic Identification of Potential Targets Unique to Candida albicans for the Discovery of Antifungal Agents

FEROZ MAZHAR ALEEM KHAN

Current Drug Targets, 2014

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Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans

sankunny M karuppayil

SpringerPlus, 2013

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Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata

Kishore Viswanathan

Journal of Medicinal Chemistry, 2014

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Multiple Drug Targeting Potential of Novel Ligands Against Virulent Proteins of Candida albicans

Anubhuti Jha

International Journal of Peptide Research and Therapeutics, 2019

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The dual role of Candida glabrata drug: H+ antiporter CgAqr1 (ORF CAGL0J09944g) in antifungal drug and acetic acid resistance

Joana Kátya Sampaio

Frontiers in Microbiology, 2013

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In vitro antifungal susceptibilities of six antifungal drugs against clinical Candida glabrata isolates according to EUCAST

Ali Zarei Mahmoudabadi

Current Medical Mycology

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Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

Dario Leonardi

BioMed Research International, 2013

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Probing the Active Site of Candida glabrata Dihydrofolate Reductase with High Resolution Crystal Structures and the Synthesis of New Inhibitors

Dennis Wright

Chemical Biology & Drug Design, 2009

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Tipping the balance both ways: drug resistance and virulence in Candida glabrata

Dominique Sanglard

FEMS Yeast Research, 2015

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Antifungal activity of fibrate-based compounds and substituted pyrroles inhibiting the enzyme 3-hydroxy-methyl-glutaryl-CoA reductase of Candida glabrata (CgHMGR), and decreasing yeast viability and ergosterol synthesis

Carlos Escalante

2021

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Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

Allan Kardec Barros

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Genome-Wide Fitness Test and Mechanism-of-Action Studies of Inhibitory Compounds in Candida albicans

John Davison

PLOS Pathogens, 2007

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Synergistic and antagonistic effects of immunomodulatory drugs on the action of antifungals against Candida glabrata and Saccharomyces cerevisiae

Peter Raspor

PeerJ

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Identification of inhibitors of yeast-to-hyphae transition in Candida albicans by a reporter screening assay

Ursula Bilitewski

Journal of Biotechnology, 2013

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Synergistic and antagonistic effects of immunomodulatory drugs on the action of 1 antifungals against Candida glabrata and Saccharomyces cerevisiae 2 3

Peter Raspor

2018

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Virulence and biofilms as promising targets in developing antipathogenic drugs against candidiasis

Abdullah ALthubiani

Future Science OA, 2020

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Heterologous expression of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provides tools for antifungal discovery

Mikhail Keniya

Antimicrobial Agents and Chemotherapy, 2018

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Inhibitors of the Glyoxylate Cycle Enzyme ICL1 in Candida albicans for Potential Use as Antifungal Agents

Lim Vuanghao

PLoS ONE

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Novel Antifungal Drug Discovery Based on Targeting Pathways Regulating the Fungus-Conserved Upc2 Transcription Factor

Geoffrey Toner

Antimicrobial Agents and Chemotherapy, 2014

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New trends in the search for alternative antifungal therapies

Monika Staniszewska

Pediatria i Medycyna Rodzinna, 2019

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Ibrexafungerp, a Novel Oral Triterpenoid Antifungal in Development: Overview of Antifungal Activity Against Candida glabrata

Ahmed Gamal

Frontiers in Cellular and Infection Microbiology, 2021

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Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata

Michael P. Lombardo

Journal of Medicinal Chemistry, 2014

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Candida glabrata Antifungal Resistance and Virulence Factors, a Perfect Pathogenic Combination

Rodolfo Pinto-Almazán

Pharmaceutics

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