Metalloenzyme-like Activity of Alzheimer's Disease β-Amyloid (original) (raw)

Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity

Lee Goldstein

Journal of Biological Chemistry, 1999

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The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures

Anthony White

1999

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A Metallo Pro-Drug to Target CuII in the Context of Alzheimer's Disease

Régis Guillot

Chemistry - A European Journal

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Cu(II) Potentiation of Alzheimer Abeta Neurotoxicity. CORRELATION WITH CELL-FREE HYDROGEN PEROXIDE PRODUCTION AND METAL REDUCTION

Joel Tyndall

Journal of Biological Chemistry, 1999

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Alzheimer's Disease Related Copper(II)- β-Amyloid Peptide Exhibits Phenol Monooxygenase and Catechol Oxidase Activities

Giordano Dasilva

Angewandte Chemie International Edition, 2005

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Copper-Dependent Inhibition of Human Cytochrome c Oxidase by a Dimeric Conformer of Amyloid- 1-42

Cyril Curtain

Journal of Neuroscience, 2005

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Neuroprotective Role of a Novel Copper Chelator againstAβ42Induced Neurotoxicity

Srikrishna Saripella

International Journal of Alzheimer's Disease, 2013

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Metalloenzyme-like Activity of Alzheimer's Disease beta -Amyloid. Cu-DEPENDENT CATALYTIC CONVERSION OF DOPAMINE, CHOLESTEROL, AND BIOLOGICAL REDUCING AGENTS TO NEUROTOXIC H2O2

Xudong Huang

Journal of Biological Chemistry, 2002

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Redox Reactions of Copper Complexes Formed with Different β-Amyloid Peptides and Their Neuropathalogical Relevance

Dianlu Jiang

Biochemistry, 2007

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The N-terminal copper-binding domain of the amyloid precursor protein protects against Cu2+ neurotoxicity in vivo

Marcelo Chacon

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Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein

Colin Masters

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002

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Copper in Alzheimer’s disease: Implications in amyloid aggregation and neurotoxicity

Patrick Gamez FRSC

AIP Advances, 2015

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2016: Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species

Sebastian K T S Wärmländer

Journal of Alzheimer's Disease, 2016

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Redox Silencing of Copper in Metal-linked Neurodegenerative Disorders: REACTION OF Zn7METALLOTHIONEIN-3 WITH Cu2+ IONS

Milan Vasak

Journal of Biological Chemistry, 2007

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Reaction Rates and Mechanism of the Ascorbic Acid Oxidation by Molecular Oxygen Facilitated by Cu(II)-Containing Amyloid-β Complexes and Aggregates

Dianlu Jiang

The Journal of Physical Chemistry B, 2010

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Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-β peptide

George Perry

Free Radical Biology and Medicine, 2007

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Molecular mechanisms underlying copper function and toxicity in neurons and their possible therapeutic exploitation for Alzheimer’s disease

Rosanna Squitti

Aging Clinical and Experimental Research, 2020

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Degradation of the Alzheimer Disease Amyloid β-Peptide by Metal-Dependent Up-Regulation of Metalloprotease Activity

R. M. Damian Holsinger

Journal of Biological …, 2006

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Towards a unified vision of copper involvement in Alzheimer's disease: a review connecting basic, experimental, and clinical research

Rosanna Squitti

Journal of Alzheimer's disease : JAD, 2015

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Oxidative processes in Alzheimer's disease: the role of Aβ-metal interactions

Toni Lynch

2000

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Glycation of Lys-16 and Arg-5 in amyloid-β and the presence of Cu2+ play a major role in the oxidative stress mechanism of Alzheimer’s disease

Sydney Shuster

JBIC Journal of Biological Inorganic Chemistry, 2017

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Copper complexing decreases the ability of amyloid beta peptide to cross the BBB and enter brain parenchyma

Shinya Dohgu

Peptides, 2007

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Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species

Shai Rahimipour

Journal of Alzheimer's Disease, 2016

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Redox-active Cu(II)–Aβ causes substantial changes in axonal integrity in cultured cortical neurons in an oxidative-stress dependent manner

Peep Palumaa

Experimental Neurology, 2012

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Metal swap between Zn7-metallothionein-3 and amyloid-β–Cu protects against amyloid-β toxicity

Peter Faller

Nature Chemical Biology, 2008

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SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease

Shigeo Murayama

Journal of Biological Chemistry, 2011

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Active-site environment of Cu bound amyloid β and amylin peptides

madhuparna roy

JBIC Journal of Biological Inorganic Chemistry, 2019

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Copper Mediates Dityrosine Cross-Linking of Alzheimer's Amyloid-β

Ashley Bush

Biochemistry, 2004

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