IN54-TH-01 Biomarkers for Alzheimer's disease from large cohort studies (original) (raw)

2009, Journal of the Neurological Sciences

AI-generated Abstract

This research discusses the Australian Imaging, Biomarkers and Lifestyle (AIBL) study aimed at recruiting 1000 participants over 60 years of age for investigating Alzheimer's disease (AD). It details the methodologies employed, participant demographics, medical histories, and cognitive assessments, highlighting the cohort's characteristics and the predictive utility of biomarkers for AD. Additionally, new research criteria for diagnosing "predementia" stages of AD are proposed, emphasizing early episodic memory impairment and the need for caution in early diagnostic disclosure due to potential psychological impacts.

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