Distribution of Helicobacter pylori Infection among Gastric Cancer in Hiwa Hospital, Sulaimani City (original) (raw)
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Incidence of helicobacter pylori infection and gastric cancer : an 8-year hospital based study
Acta medica Indonesiana
To observe the tendency of decreased prevalence of H pylori infection in a 14 year-period and observe the prevalence of intestinal metaplasia and gastric cancer. All patients who were diagnosed with dyspepsia and underwent esophagogastroduodenoscopy in Cikini hospital Jakarta from January 1998 until December 2005 were evaluated. We evaluated the histopathologic result of H pylori, the presence of intestinal metaplasia and gastric cancer. Data was grouped for 1 year period of time and was presented descriptively. Decreased prevalence of H. Pylori infection was found, from 12.8% in 1998, 12.4% in 1999, 14.7% in 2000, 9.6% in 2001, 11.9 % in 2002, 3.8% in 2003, 2.3% in 2004, 2.9% in 2005. Intestinal metaplasia was 4.7% in 1998, 3.2% in 1999, 3.1% in 2000, 2.3 % in 2001, 7.6% in 2002, 8.3% in year 2003, 6.5% in 2004, 7.1% in 2005. Prevalence of gastric cancer was 2.2% in 1998, 0.25% in 1999, 1.1% in 2000, 1.1% in 2001, 1.1% in 2002, 1.8% in 2003, 1.7% in 2004, 3.9% in 2005. There was de...
Diagnostic and Therapeutic Endoscopy, 1997
Objective: The aim of the present study was to assess the prevalence of Helicobacter pylori (H. pylori) infection in Kashmiri patients with gastric cancer and to compare this with a matched control population.Methods: Fifty patients with gastric cancer and thirty age/sex matched controls were included in the study. All the subjects were hailing from Kashmir Valley. For detection of H. pylori, biopsy specimens were used both from cases and controls.Results: An insignificant association was shown between H. pylori and both intestinal and diffuse type of gastric cancer.Conclusions: The data provides support against the significant association between H. pylori and gastric cancer in this part of world, a place where the age standardized incidence of gastric cancer is alarmingly high. We conclude that other factors like personal and special dietary habits of Kashmiri population may be more important for the development of gastric cancer.
Association of Helicobacter Pylori Infection and Gastric Cancer
Post-Graduate Medical Journal of NAMS, 2015
Introduction: Gastric cancer remains one of the most common cancers worldwide and the second leading cause of cancer mortality in the world. Helicobacter Pylori is a major risk factor. Early detection of infection and eradication therapy will probably reduce the incidence of stomach cancer. This study is carried out to see the association of the H. pylori infection in gastric cancer patients in our population. Methods: This is a prospective cross sectional descriptive study done in Gastroenterology unit, Department of medicine, National Academy of Medical Sciences, Bir Hospital. Patients who were suspected of cancer of stomach clinically as well as endoscopically,their thorough history was taken and demographic profiles like age, sex and geographic location were recorded. Similarly, symptoms, risk factors and endoscopic finding were recorded. Likewise, result of rapid urease test and histopathology results were documented. Results: Male patients were seen to be more frequently affec...
Incidence of gastric cancer, its subtypes, and correlation with Helicobacter Pylori
Journal of Pathology of Nepal, 2013
Background: Gastric cancer is the fourth most commonly diagnosed cancer and the second most common cause of cancer related death worldwide. It is the common cause of cancer related death in Nepal. Helicobacter Pylori has been classified as a definite carcinogen along with other factors. The aim of this study was to fi nd the incidence of gastric cancer among the patients undergoing upper gastroscopy, its various subtypes and association with Helicobacter Pylori. Materials and Methods: This is a retrospective and prospective study carried out at GRP Polyclinic and Kist Medical College Teaching Hospital. All the patients undergoing upper gastrointestinal endoscopy were included in this study. Data of all the gastric endoscopic biopsies done from June 2011 to January 2013 were collected and analyzed. All the biopsy specimens were processed routinely in histopathology laboratory. Specimens showing carcinoma were enrolled in this study and all the relevant demographic data were collected...
Middle East Journal of Digestive Diseases, 2022
Background: Despite all improvements in sanitation and exposure to antibiotics over time, Helicobacter pylori (HP) prevalence remains high, affecting the lives of about half of the world population, which can gradually lead to serious upper gastrointestinal disorders. Understanding HP's epidemiologic patterns help us to better manage the burden of this infection and to plan more effectively regarding potential screening or eradication strategies. We, therefore, aimed to report the crude and age-and sex-standardized prevalence rate of HP infection, its trend, and possible associated factors among asymptomatic healthy individuals in Rafsanjan city, a low-incidence area of gastric cancer (GC) in the southeast of Iran, from July 2018 to December 2021. Methods: This population-based cross-sectional descriptive study included 2,046 male and female subjects between 3 to 72 years who were in good health condition. Study participants were randomly selected from the Health Houses and each underwent a questionnaire-based interview and provided blood and feces samples. The presence of HP infection was detected by serum IgG antibodies and stool antigen test. Results: The overall and age-and sex-standardized prevalence rates of HP infection were 50.9% and 43%, respectively. The prevalence rate has notably decreased in all age groups compared with 2007. Also, it was significantly higher among men (P = 0.033) and increased with advancing age (P < 0.001). A higher population density living in a specific room area (P = 0.012) increased the likelihood of HP infection. Conclusion: To conclude, the prevalence of HP infection is decreasing over time in Rafsanjan city, which may be due to improvements in living standards in this area. A healthy lifestyle and adherence to hygienic principles, especially during childhood, may be required for a reduction in the prevalence of HP infection.
The Prevalence of Helicobacter Pylori and Gastritis in Western Uttar Pradesh
International Journal of Contemporary Surgery, 2016
Helicobacter pylori (H. pylori), a gram negative spiral shaped bacillus, is considered to be the most common human infectious agents leading to gastritis, ulcer and probably stomach cancer. In fact, it is classified as a class I carcinogen 1 for gastric cancer. Despite the success in several diagnostic methods for the detection of H. pylori such as endoscopy, urea breath test, stool and blood samples and the improvement in socioeconomic status, infection with H. pylori is still on rise. In developing countries such as Ethiopia, India, Sri Lanka, Bangladesh, Mexico and Brazil, the prevalence of H. pylori infection is 80% whereas in the developed countries such as USA, Canada, Australia, Netherland and Switzerland, the 2,3 prevalence is only 30%. In addition to the socioeconomic status, age, gender, ethnicity, sanitation, educational level and genetic predisposition are important factors that affect the prevalence of H. pylori infection. Unfortunately and according to our knowledge, there are no data on the prevalence of H. pylori in Oman. Thus the aim of this study was to evaluate the relationship between H. pylori infection and stomach diseases in Oman using endoscopy biopsy of the stomach. Methods This retrospective study was approved by the Medical Research Committee and Ethics Committee (MREC # 520
Biomedical Journal of Scientific & Technical Research (BJSTR, 2018
Helicobacter pylori (H. pylori) are a common chronic infection that is responsible for causing several gastroduodenal diseases and accounts for 84.3% of Gastric Cancer. The proposed study aimed at finding the frequency of H. pylori infection and its associated risk factors in patients with gastric problems from Mardan, Khyber Pukhtunkhwa Pakistan. We carried out a cross-sectional study that included 200 subjects of age groups 11-50 years who underwent screening method of Immune Chromatographic Technique (ICT) in major hospitals of Mandan city. Results showed that 94 (47%) subjects were found positive for H. pylori in which males were 63 (67%) and females were 31 (33%). Based on the multivariate analysis frequency rate of H. pylori was higher as 41 (43%) subjects each in age groups 11-20 years and 21-30 years followed by 10 (10.60%) with age group of 31-40 years and 2 (2.12%) with age group of 41-50 years. Irrespective of age groups frequency rate was high in 30 (31.19%) subjects infected with indigestion problems. Those subjects who were educated had a higher frequency rate of 68 (72.34%) as compared to illiterate 26(27.65%). Our study concluded that frequency of H. pylori in Mardan was observed to be very high (47%) among the subjects wit
Clinical Characteristics and Helicobacter pylori Status of Gastric Cancer in Thailand
Asian Pacific Journal of Cancer Prevention, 2014
Background: Gastric cancer is the second leading course of cancer death worldwide and H. pylori infection is an important risk factor for gastric cancer development. This study was design to evaluate the clinical, pathological features, survival rate and prevalence of H. pylori infection in gastric cancer in Thailand. Materials and Methods: Clinical information, histological features, endoscopic findings and H. pylori status were collected from gastric cancer patients from Thammasat university hospital during June 1996-December 2011. H. pylori infection was assessed by histological evaluation, rapid urease test and serological test. Clinical information, endoscopic findings and histopathology of all patients were recorded and compared between patients with active or non-active H. pylori infection. Results: A total of 100 gastric cancer patients (55 men and 45 women with mean age of 55±16.8 years) were enrolled in this study. Common presenting symptoms were dyspepsia (74%), weight loss (66%), anemia (63%) and anorexia (38%). Mean duration of symptoms prior to diagnosis was 98 days. Overall prevalence of H. pylori infection was 83% and active H. pylori infection was 40%. 1-year and 5-year survival rates were 43% and 0%. There was no significant difference between active H. pylori infection in different locations (proximal vs non-proximal: 47.1% vs 48.5%; P-value = 0.9, OR=0.9; 95%CI =0.3-3.1) and histology of gastric cancer (diffuse type vs intestinal type: 47.4% vs 50%; P-value= 0.8, OR=0.9, 95%CI=0.3-2.7). However, linitis plastica was significantly more common in non-active than active H. pylori infection (27.9% vs 0%; P-value <0.0001, OR =13.3, 95%CI=3.2-64.5). Moreover, gastric cancer stage 4 was higher in non-active than active H. pylori infection (93% vs 50%, P-value<0.001). Conclusions: Prevalence of H. pylori infection in Thai gastric cancer patients was high but active infection was low. Most gastric cancer patients presented in advance stage and had a grave prognosis. Screening for gastric cancer in high risk individuals might be an appropriate tool for early detection and improve the treatment outcome for this particular disease in Thailand.
Detection of Helicobacter pylori among gastritis patients attending Nemba district hospital
African Journal of Biological Sciences, 2019
Background: Helicobacter pylori (H. pylori) is a small, spiral-shaped bacterium that lives in the surface of the stomach and duodenum. More than half of the world's population is colonized with H. pylori in the gastric mucosa which is the major cause of chronic gastritis, peptic ulcer and also the most important etiological factor responsible for the duodenal and gastric ulcer and has an important role in the pathogenesis leading to gastric cancer. Objectives: The objectives of this study was to determine the prevalence of H. pylori among gastritis patients at Nemba district hospital, to compare sex prevalence level of H. pylori among gastritis patients and determine the prevalence of H. pylori among gastritis patients according to the age of gastritis patients. Methods: This study involved 140 patients with gastritis who attended Nemba district hospital from August to October 2018. The samples were collected and H. pylori rapid test strip was performed for all patients to diagnose H. pylori among gastritis patients. Results: Findings of the study showed that the prevalence of H. pylori infection was found to be significantly high among female participants than male participants. Despite high prevalence in females, the findings showed that there was no statistical significance of sex with H. pylori infection ( 2 = 0.6 and p > 0.05, p = 0.1). On basis of age, the prevalence of H. pylori infection was found to be high among participants and the prevalence increase between young age and old age. Results show that there was statistical significance between age and H. pylori infection with 2 = 1.2 and p > 0.05, p = 0.04. the group of individuals with that 45 years old were more affected compared to other age groups and the prevalence of H. pylori infection was increased in older patients than younger patients. Our study showed an overall prevalence of H. pylori among gastritis patients was (45.7% n = 140). Conclusion: H. pylori infection is terrible burden of public health and affect people of all age and sex. H. pylori infection was significantly high in females and significance was found in age group of patients. Number of people are carrier of this terrible bacterium, thus hospitals are recommended to carry out early diagnosis to avoid later complication of infection.