Mixed schwannoma with meningioma of the trigeminal nerve (original) (raw)
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European Journal of Radiology Extra, 2010
Type 2 neurofibromatosis is an autosomal dominant disease characterized by the development of bilateral vestibular schwannomas. We are presenting a rare case of NF2 with multiple cranial nerve schwannomas involving the 3rd, 4th, 5th, 7th, 8th, 9th, 10th and 11th cranial nerves with multifocal cystic meningiomatosis and fourth ventricle ependymoma these findings were better depicted on high field MR using 3D FIESTA which has obviated the need of contrast MRI in this particular case.
Interdisciplinary Neurosurgery, 2017
Neurofibromatosis type 2 (NF-2) is an autosomal dominant inheritance, chromosome 22q12 mutations in peripher and central nervous systems. Several literatures have discussed rare cases of triple NF-2 tumor, known as multiple inherited Schwannomas, meningiomas and ependymomas or MISME. Incidence of MISME reported from many country, but never been reported from Indonesia. Hopefully the MISME presence can be more revealed in our country and adding the evidence in world literature. A 15-year-old boy presented to our center with a progressive bilateral hearing loss for 2 years and started to experience weakness of both lower extremities since 1.5 years. Patient underwent both craniotomy intracranial and spinal tumor removal. Histopathological result showed Schwannomas, meningiomas and ependymoma. Diagnosis of MISME was made and had been treated with excellent clinical outcome. We are reporting a rare case of MISME syndrome, which is an extremely exceptional case in our center due to rare occurrence of MISME and the need to confirm NF-2 diagnosis using molecular investigations.
European Journal of Radiology Extra, 2005
Cervical meningiomas and schwannomas are relatively common neoplasms of the central nervous system but cervical dumbbell meningioma and bilateral schwannoma in the same patient in neurofibromatosis type 2 are rare. We report a case of a 16-year-old girl who presented with a history of slowness in performance for 1 year, decreasing weight for the last 7 months and weakness of the left lower limb for 6 months. There was no café-au-lait spot noted. MR imaging revealed a cervical extradural tumor with bilateral foraminal extension at the C4-5 and bilateral cerebellopontine angle tumors. A diagnosis of neurofibromatosis type 2 was made. The histopathological examination revealed meningioma. Follow up examination with magnetic resonance imaging (MRI) of the brain and spinal cord in a patient with neurofibromatosis type 2 should be performed to detect the recurrent tumours at these sites.
Superficial neurofibromas in the setting of schwannomatosis: nosologic implications
Acta Neuropathologica, 2010
First described in the past decade, schwannomatosis is a syndrome distinct from neurofibromatosis 2 (NF2). It is characterized by the development of multiple schwannomas, sparing the vestibular division of cranial nerve VIII, and may also predispose to develop meningiomas. We report two female patients, a 27 and a 44 years old who developed multiple peripheral schwannomas, but without involvement of the vestibular nerves, satisfying clinical criteria for schwannomatosis. Lack of vestibular nerve involvement was confirmed with MRI using an internal auditory canal protocol with 3 mm thick slices in both patients after age 30. Both patients developed a small neurofibroma in axillary subcutaneous tissues and a diffuse cutaneous neurofibroma of the left buttock, respectively. This report highlights that superficial neurofibromas may arise in the setting of schwannomatosis, which may have implications for the diagnostic criteria of this unique syndrome. In particular, the presence of a cutaneous neurofibroma in a patient with multiple schwannomas should not lead to a diagnosis of NF2.
Intracerebral Schwannoma Mimicking Meningioma: Case Report
The Canadian Journal of Neurological Sciences, 2013
Intracranial schwannomas account for 8% of all primary brain tumors, approximately 80-90% of them being seen in the cerebellopontine angle in relation to the vestibular nerve. Schwannomas arising within brain parenchyma, unrelated to the cranial nerves, are extremely rare. To our knowledge, only 73 cases of intracerebral schwannoma have been described in the English-language literature so far,1-5 but only six cases of intracerebral schwannoma mimicking meningioma have been reported1-3 and there have been few reports regarding neuroradiological findings. Disagreement remains concerning the histogenesis of these tumors.
Int J Otorhinolaryngol, 2005
Extracranial meningiomas, either primary or secondary, are rare. Reported incidences are between 0.9 and 2.0% respectively. The most common form is cutaneous, and, orbital, paranasal, temporal and oral presentations following in descending order. Meningiomas are not usually considered in the differential diagnosis of neck swellings. One such rare clinical case where presentation was a neck mass along with oropharyngeal bulge associated with asymptomatic bilateral acoustic neuromas is presented here along with review of relevant literature. The patient underwent successful excision of cervical mass