The “ECG modifications induced by the disturbance of the circadian rhythm in night-shift workers (ECGNoct)” study protocol (original) (raw)
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Changes in heart rate variability during working and non-working nights
2011
The aim of this study was to compare levels and patterns of heart rate variability during working night shifts and the same period of non-working nights. Eight nurses from the Surgical Department of Zadar Hospital, aged 25-33, participated in this study. The study included continuous recordings of cardiac activity during 10 hours of night-shift working (9.00 pm – 7.00 am) and during the equivalent non-working night periods. As expected, the analyses showed differences in the levels of cardiac activity between working and nonworking nights. Non-working nights were characterised by longer R-R intervals, higher variability indices and greater parasympathetic effects on cardiac activity, while their patterns of changes and spectral compositions were rather similar to those obtained during working nights. The obtained results showed the supremacy of the circadian pattern of changes, i.e. parasympathetic prevalence, during both working and non-working nights. Parasympathetic prevalence du...
Background. Epidemiologic evidence indicates that sleep loss may be a novel risk factor for cardiovascular diseases (CVDs); hypertension, coronary artery disease (CAD) and stroke. The increased risk of CVDs is possibly linked to the effect of sleep loss on hormones that play a major role in the central control of blood pressure and heart rate variability, also on angiotensin, cytokines, appetite and energy expenditure as well as sympathetic and vagal activity, melatonin and serotonin. Methods. Internet search and expert opinion from colleagues. Results. Exposure to light at night disturbs the circadian system with alterations of the sleep/activity patterns and suppression of melatonin production. Light is the most powerful synchronizer but, when exposure occurs at a time when the body would normally not be exposed to light, (that is, at night), then it disrupts the circadian rhythms. In developed countries, approximately, one fifth of the workers may have disruption of sleep due to night shift and may be unable to tolerate exposure to light during this time. Daily physiological variations include normal circadian rhythms which are interactive and require a high degree of phase positioning to produce subjective feelings of well being. Disturbances in these activities, may predispose circadian desynchronization, (whether from passage over time zones or from shift rotation), resulting in disturbance of the quantity and quality of sleep leading to hormonal and cardiovascular dysfunction. Shift work can increase the risk of CVD by several interrelated psychosocial, behavioral, and physiological mechanisms. Biological mechanisms are related to the activation of the autonomic nervous system, inflammation, dyslipidemia and glucose intolerance, which may increase the risk for atherosclerosis, metabolic syndrome and insulin resistance resulting in CAD, hypertension and stroke. It is important to promote greater changes in behavioural factors like physical activity, Mediterranean-style diet and meditation apart from providing rotation in shift to cover the loss of sleep. Conclusions. Disruption of sleep has become a public health problem due to industrialization and urbanization. Strategies to reduce the potential for circadian disruption, including extending the daily dark period, appreciating nocturnal awakening in the dark, using dim red light for R. B. Singh, B. Anjum, Rajiv Garg et al. 24 night-time necessities, and avoiding frequently rotating shifts. There is a need to have more intensive guidelines on dietary intakes, physical activity and meditation to prevent CVDs among subjects who have significant sleep disruption.
Disruption in Circadian Rhythm Increases Cardiovascular Disease Risk Factors in Shift Working Nurses
Indian Journal of Cardiovascular Disease in Women - WINCARS
Background Shift work is associated with behavioral, psychosocial, and physiological consequences in the body that may cause cardiovascular disease (CVD) risk. Therefore, in this study we tried to demonstrate the disruption in circadian rhythm of blood pressure by ambulatory blood pressure monitor in shift working nurses. Methods A total of 50 nurses, 25 night shift working nurses (NSWN), and 25 day shift working nurses (DSWN) underwent ambulatory blood pressure monitoring (ABPM) for a period of 24 hours. Along with measurements of inflammatory markers (hs-CRP and IL-6) the risk factors for cardiovascular disease between NSWN and DSWN and their possible relationship with disrupted circadian rhythm were measured by circadian rhythm questionnaire. Results The mean systolic and diastolic pressure for a period of 24 hours and mean diastolic blood pressure analysis throughout the sleep time was found greater in the NSWN than the DSWN (118 mm Hg vs. 112 mm Hg, p < 0.05: 72 mm Hg vs. 68...
The aim of this study was to compare levels and patterns of heart rate variability during working night shifts and the same period of non-working nights. Eight nurses from the Surgical Department of Zadar Hospital, aged 25-33, participated in this study. The study included continuous recordings of cardiac activity during 10 hours of night-shift working (9.00 pm – 7.00 am) and during the equivalent non-working night periods. As expected, the analyses showed differences in the levels of cardiac activity between working and non-working nights. Non-working nights were characterised by longer R-R intervals, higher variability indices and greater parasympathetic effects on cardiac activity, while their patterns of changes and spectral compositions were rather similar to those obtained during working nights. The obtained results showed the supremacy of the circadian pattern of changes, i.e. parasympathetic prevalence, during both working and non-working nights. Parasympathetic prevalence d...
International Journal of Environmental Research and Public Health
There is a plausible association between shift work and cardiovascular disease (CVD), which may be due to disruption of the circadian rhythm causing hormonal changes and metabolic disturbances, resulting in high blood pressure, atherosclerosis, diabetes, and being overweight. However, few studies have investigated the association between several consecutive long work shifts, including night shifts, and risk factors for developing CVD. Moreover, knowledge is lacking on factors that may modify or enhance this suggested relationship. The study period is planned from the third quarter of 2018 to the fourth quarter of 2021, and will involve 125 industrial employees at two Norwegian enterprises producing insulation. The work schedule is either rotating shiftwork (morning, evening, night) or regular day work. At baseline, we will measure blood parameters, including markers of inflammation, lipids, and glycosylated hemoglobin. We will also collect measures of blood pressure, resting heart r...
Background: Night work is associated sleep deprivation, where the person's internal body clock is in conflict with the rotating shift schedule leads to circadian disruption of various physiological rhythms like blood pressure, heart rate, and various hormones. Night shift workers have altered circadian pattern of blood pressure/heart rate. Due to this variation, night shift worker suffers from various cardiovascular and circadian rhythm disorders. Objective: The Present study was aimed to investigate the effects of rotating night shift on 24 hours chronomics of blood pressure and heart rate in terms of double amplitude, acrophase and hyperbaric index. Materials and Methods: 62 healthy nursing professionals, aged 20-40 year, performing day and night shift duties were recruited. This was the prospective observational study. Each month scheduled to continuous 9 days night shift (12 hours in regular 9 nights, from 20:00 to 08:00); after 9 days night shift they perform remaining duti...
Assessment of cardiovascular risk in shift healthcare workers
European Journal of Cardiovascular Prevention & Rehabilitation, 2008
Background Shift work has been associated with an increased risk of cardiovascular disease (CVD); in particular, night work affects the circadian rhythm. Design and methods The study examines the effectiveness of three screening methods and plasma hyperhomocysteinemia, an independent risk factor, in assessing the risk of CVD in 147 healthcare providers doing daytime or rotational shift work. The methods applied were: (i) the method proposed by the European Cardiovascular Indicators Surveillance Set (EUROCISS); (ii) the metabolic syndrome (MS) criteria of the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATPIII) and (iii) the MS criteria of the International Diabetes Federation (IDF). Results EUROCISS was unable to distinguish between the CVD risk of daytime and rotational shift workers. Both the ATPIII and the IDF detected MS, which is strongly associated with CVD, but only the IDF evidenced a significantly greater prevalence of MS (P < 0.05) among shift workers. Hyperhomocysteinemia was unable to discriminate the CVD risk between daytime and shift workers, as it was influenced by multiple confounding factors. Conclusions The increased risk of CVD associated with shift work is related to the greater incidence of MS among these workers. In our study a high prevalence of MS was detected only with the IDF. The method is useful for CVD prevention and the promotion of health during any medical examination of shift workers. Eur J Cardiovasc Prev Rehabil 15:224-229
Circadian heart rate variability rhythm in shift workers
Journal of Electrocardiology, 1997
The objective of this study was to assess the influence of day-night cycle and sleep-awake period on the circadian pattern of heart rate variability (HRV). Twelve male oil refinery security shift workers, aged 39 _+ 7 years, 'were studied with 24-hour Holter monitor recordings during morning and :night work periods. Hourly HRV parameters in the time and frequency domains were evaluated. For both shifts, all HRV parameters during awake or work periods were found not to be statistically different. In both day and night work shifts, the very low frequency and high-frequency components of HRV and the proportion of differences in successive R-R intervals greater than 50 ms increased during the sleep period, while the low frequency/high frequency ratio decreased. The low-frequency component in absolute units and the SD of the R-R interval did not show any variation in either shifts for the different periods. These results suggest that the circadian pattern of HRV seems to be predominantly related to sleep (supine) and wakefulness (standing) and remains independent of night-day cycle. Key words: circadian rhythm, heart rate variability, shift workers, autonomic nervous system.
Shift work and its effects on the cardiovascular system
Cardiovascular Journal of Africa, 2008
The practice of shift-work scheduling has long been part of normal work duties in emergency services such as health and security. it is only recently, in the wake of growing job opportunities and booming industries, where more employees are needed to keep services running over 24-hour periods that studies on the effects of shift work on workers' health have begun to delve deeper. The desynchronisation that occurs in circadian rhythms, with respect to sleep cycles, predisposes employees to coronary heart disease, gastrointestinal disturbances, increased risk of breast cancer and poor pregnancy outcomes. This literature review focuses on circadian rhythms, their molecular components, disturbances of these rhythms as a result of shift work and the adverse effects thereof on the cardiovascular system.