Utilization of Ginger and Its Effect on Relieving Chemotherapy Related Nausea and Vomiting Among Patients with Gynecological Cancer (original) (raw)
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Effect Of Ginger Infusion On Chemotherapy Induced Nausea And Vomiting In Breast Cancer Patients
Journal of Biology Agriculture and Healthcare, 2013
Nausea and vomiting are the most common side effects of chemotherapy. Ginger is one of complementary therapy to treat nausea and vomiting. The purpose of this study was to determine the effect of ginger infuse for nausea and vomiting side effects of chemotherapy in breast cancer patients. Control Time Series Design was used to collect the data. Purposive sampling technique was used to get sample with total sample was 20 people. Rhodes Index Nausea Vomiting and Reching were used for scaling nausea and vomiting. Therapy was given from second until sixth day after chemotherapy. Data analized with Friedman Test and Mann-Whitney Test. The results of this study showed that the significant decreased of nausea and vomiting in experimental group (p = 0.000) is better than control grup (p=0,011). Differences nausea vomiting experimental group and the control group significant with value of p = 0.036. It is recommended to use ginger as a complementary therapy in the management of Chemotherapy Induced Nausea and Vomiting.
Canadian Oncology Nursing Journal
Chemotherapy has serious side effects that may be detrimental to the patient, namely complaints of nausea and vomiting. To reduce the side effects of chemotherapy, many patients in our country choose herbal therapy. One such therapy is the intake of ginger. The aim of this article is to explore the effectiveness of ginger to overcome nausea and vomiting caused by chemotherapy in breast cancer patients. The method used is a systematic review. Results of the study suggest that ginger is only effective to reduce nausea, but does not lower the frequency of vomiting caused by chemotherapy in breast cancer patients.
Aromatherapy Ginger Use in Patients with Nausea Vomiting on Post Cervical Cancer Chemotherapy
Jurnal Kesehatan Masyarakat, 2017
Chemotherapy is an effective treatment for cancer. However, it causes some side effects which include nausea and vomiting. More than 70% of patients experience nausea and vomiting after chemotherapy. The purpose of this study was to determine the effect of ginger aromatherapy in nausea, and vomiting patients on post cervical cancer chemotherapy. We used a pretest-posttest control group design, using purposive sampling of 60 respondents. We used anti-emetics measurement tool according to Multinational Association of Supportive Care in Cancer (MASCC) to assessed patients complaints. The result showed significant difference in nausea and vomiting group before and after given aromatherapy (p = 0.000); nausea score (p = 0.005) and vomiting score (p= 0.013) from intervention and control group. No significant difference was observed in nausea (p = 0.279), and vomiting (p = 0.276) on control group. Ginger aromatherapy can be used as alternative medication to reduce post-chemotherapy nausea ...
2016
BACKGROUND Chemotherapy-induced nausea and vomiting (CINV) places a significant burden on the patient. Herbal agents are the most commonly complementary therapies used among the public. This study was done to determine the effect of ginger and chamomile capsules on nausea and vomiting in cases undergoing chemotherapy for breast cancer (BC). MATERIALS AND METHODS In a randomized, double-blind and clinical trial study, 65 women with BC undergoing chemotherapy were referred to Breast Cancer Research Center, Tehran, Iran, between May 2013 to June 2014. Regimen for ginger group for 5 days before and 5 days after chemotherapy was: 2 times a day and 500 mg capsules of powdered ginger root in addition to a routine antiemetic regimen consisting of dexamethasone, metoclopramide and aprepitant (DMA) capsules. Chamomile group similarly was: 2 times a day and 500 mg capsules of Matricaria chamomilla extract in addition to a routine antiemetic regimen consisting of DMA capsules. Control group, ro...
International Journal of Research in Pharmaceutical Sciences, 2020
A quasi-experimental research study (posttest only research design) was conducted to evaluate the effect of ginger tea on chemotherapy-induced nausea and vomiting among cancer patients in selected hospitals of Bhubaneswar and to find out the association of level of chemotherapy-induced nausea and vomiting with selected socio-demographic variables. For this study, a quantitative experimental approach and post-test only research design was adopted. 100 patients were selected by convenience sampling technique and categorized into experimental (n=50) and control group (n=50) for this study. Self- structured socio-demographic proforma and self- structured record analysis proforma was used to collect socio-demographic data and modified nausea and vomiting scale was used to measure the level of chemotherapy-induced nausea and vomiting among cancer patients. The data was analyzed by using SPSS version 20.0 (Statistical Package for the Social Science). The post-testt level of chemotherapy-in...
Benefits of ginger in the control of chemotherapy-induced nausea and vomiting
Revista Brasileira de Enfermagem
Objectives: To identify and discuss scientific evidence of the effects of ginger use on the management of chemotherapy-induced nausea and vomiting. Methods: This is an integrative reviewperformed by Ganong’s reference. Results: We included 24 studies, highlighting three thematic categories, namely 1) antiemetic action of ginger - nausea (13 articles; of these, nine significant) and emesis (10 studies; of these, six significant); 2) action in the control of nausea (11 articles; of these, six significant) and vomiting (8 articles; of these, three significant) in the acute phase; 3) action in the control of nausea (6 articles; of these, three significant) and vomiting (6 articles; of these, three significant) in the delayed phase. There were divergences of the methods used. Final considerations: This complementary therapy has low cost and easy access, but no statistical confirmation of its effectiveness in the management of nausea and vomiting in cancer patients was found.
Asian Pacific journal of cancer prevention : APJCP, 2016
Nausea and vomiting are among the most serious side effects of chemotherapy, in some cases leading to treatment interruption or chemotherapy dose reduction. Ginger has long been known as an antiemetic drug, used for conditions such as motion sickness, nausea-vomiting in pregnancy, and post-operation side effects. One hundred and fifty female patients with breast cancer entered this prospective study and were randomized to receive ginger (500 mg ginger powder, twice a day for 3 days) or placebo. One hundred and nineteen patients completed the study: 57 of them received ginger and 62 received ginger for the frst 3 chemotherapy cycles. Mean age in all patients was 48.6 (25-79) years. After 1st chemotherapy, mean nausea in the ginger and control arms were 1.36 (±1.31) and 1.46 (±1.28) with no statistically significant difference. After the 2nd chemotherapy session, nausea score was slightly more in the ginger group (1.36 versus 1.32). After 3rd chemotherapy, mean nausea severity in cont...
Efficacy of The Ginger on Chemotherapy-Induced Nausea andVomiting (CINV): A Systematic Review
2018
Background: Chemotherapy Induced Nausea-Vomiting (CINV) is a frequent side effect experienced by sufferers of malignant tumor undergoing chemotherapy. Ginger is one herb that has been used since many years and is naturally especially as antiemetic. This study aims to find out the effectiveness of ginger against nausea vomiting due to chemotherapy by systematic review and followed the PRISMA statement guidelines. Methods: Scopus, Science Direct, PubMed, and Springerlink database from January 2012 – December 2017. Articles identified by using search terms or keywords ('CINV' OR 'nausea' OR 'vomiting' OR 'emesis') AND (‘chemotherapy’) AND ('ginger' OR 'Zingiber officinale' OR 'rhizoma'). All included studies were access base on randomized controlled trial. Results: 14 out of 209 papers were including. Articles that have been reviewed results that ginger give benefits to reduce nausea vomiting due to chemotherapy showed a significa...
BMC Complementary and Alternative Medicine, 2014
Background: Preliminary research shows ginger may be an effective adjuvant treatment for chemotherapy-induced nausea and vomiting but significant limitations need to be addressed before recommendations for clinical practice can be made. Methods/Design: In a double-blinded randomised-controlled trial, chemotherapy-naïve patients will be randomly allocated to receive either 1.2 g of a standardised ginger extract or placebo per day. The study medication will be administrated as an adjuvant treatment to standard anti-emetic therapy and will be divided into four capsules per day, to be consumed approximately every 4 hours (300 mg per capsule administered q.i.d) for five days during the first three cycles of chemotherapy. Acute, delayed, and anticipatory symptoms of nausea and vomiting will be assessed over this time frame using a valid and reliable questionnaire, with nausea symptoms being the primary outcome. Quality of life, nutritional status, adverse effects, patient adherence, cancer-related fatigue, and CINV-specific prognostic factors will also be assessed. Discussion: Previous trials in this area have noted limitations. These include the inconsistent use of standardized ginger formulations and valid questionnaires, lack of control for anticipatory nausea and prognostic factors that may influence individual CINV response, and the use of suboptimal dosing regimens. This trial is the first to address these issues by incorporating multiple unique additions to the study design including controlling for CINV-specific prognostic factors by recruiting only chemotherapy-naïve patients, implementing a dosing schedule consistent with the pharmacokinetics of oral ginger supplements, and independently analysing ginger supplements before and after recruitment to ensure potency. Our trial will also be the first to assess the effect of ginger supplementation on cancer-related fatigue and nutritional status. Chemotherapy-induced nausea and vomiting are distressing symptoms experienced by oncology patients; this trial will address the significant limitations within the current literature and in doing so, will investigate the effect of ginger supplementation as an adjuvant treatment in modulating nausea and vomiting symptoms.
Nutrients
Ginger supplementation could be an effective adjuvant treatment for chemotherapy-induced nausea (CIN). The aim of this clinical trial was to address significant methodological limitations in previous trials. Patients (N = 51) were randomly allocated to receive either 1.2 g of standardised ginger extract or placebo per day, in addition to standard anti-emetic therapy, during the first three cycles of chemotherapy. The primary outcome was CIN-related quality of life (QoL) measured with the Functional Living Index-Emesis (FLIE) questionnaire. Secondary outcomes included acute and delayed nausea, vomiting, and retching as well as cancer-related fatigue, nutritional status, and CIN and vomiting-specific prognostic factors. Over three consecutive chemotherapy cycles, nausea was more prevalent than vomiting (47% vs. 12%). In chemotherapy Cycle 1, intervention participants reported significantly better QoL related to CIN (p = 0.029), chemotherapy-induced nausea and vomiting (CINV)-related QoL (p = 0.043), global QoL (p = 0.015) and less fatigue (p = 0.006) than placebo participants. There were no significant results in Cycle 2. In Cycle 3, global QoL (p = 0.040) and fatigue (p = 0.013) were significantly better in the intervention group compared to placebo. This trial suggests adjuvant ginger supplementation is associated with better chemotherapy-induced nausea-related quality of life and less cancer-related fatigue, with no difference in adverse effects compared to placebo.