The effect of high dose medroxyprogesterone acetate on water and salt metabolism in advanced cancer patients (original) (raw)

Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1984

Abstract

Ten advanced cancer patients (both with hormone-sensitive and non-hormone sensitive tumors) were treated with high dose medroxyprogesterone acetate (MAP, greater than 500 mg/day). We determined body weight, lean body mass, blood pressure, sodium blood level, urinary excretion, and exchangeable sodium pool by the 22Na method before and after treatment. These data seem to exclude a fluid retentive effect for high-dose MAP.

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