Epidemiology of brain tumors in the United Arab Emirates: a National Registry Cross-sectional Study (original) (raw)
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Epidemiology of Brain Tumors in Qatar
Journal of Epidemiology and Public Health Reviews
Background: Brain tumors in general are rare tumors and their epidemiologic features in the Middle East including the state of Qatar is rarely tackled. The objective of this study is to delineate the epidemiologic characteristic of brain tumors in the gulf state of Qatar. Methods: We run a retrospective analysis of brain tumors diagnosed histologically in the main Hospital in Qatar between January 1 st , 2006-December 31 st 2015. We studied the following indices: Histologic type, gender, age, and location. We obtained the demographic data from Qatar Planning and Statistic Authority (www.psa.gov.qa). Results: A total of 383 cases of primary brain tumors were identified and analyzed during the 10 years period studied. The incidence rate of primary brain tumors is 2.2/100,000 population. Normalized Male/Female ratio is 0.93:1. The commonest histological subtypes were Meningioma (21.9%) and Glioblastoma (18.3 %) followed by Astrocytoma (G2-G3) (18%) and Oligodendroglioma (15.1%). Conclusion: Brain tumors incidence in the state of Qatar is low (2.2/100,000) when compared to developed countries which may reflects the young age population.
Epidemiology of Malignant and Non-Malignant Primary Brain Tumors in Jordan
Neuroepidemiology, 2015
There is lack of knowledge on the epidemiological characteristics of brain tumors in Middle Eastern countries. The objective of this study was to study the epidemiological features of primary brain tumors in Jordan. We conducted a prospective cohort study incorporating data from 16 hospitals in Jordan during a 1 year period (May 1, 2011-April 30, 2012). All primary brain tumors diagnosed in Jordan during the study period were identified. The following parameters were retrieved from patients' files: age, gender, histological type, and location. The demographic data of the country was obtained from the National Department of Statistics. A total of 313 primary brain tumors were identified during the study period. The incidence of primary brain tumors in Jordan among the general population was 5.01 per 100,000 person-years (5.38 in females and 4.65 in males). The incidence in pediatric, adult, and elderly patients was 2.09, 7.29, and 14.38 per 100,000 person-years, respectively. The...
Neuroepidemiology, 2021
Background: Primary brain tumors are among the main causes of death. This study aimed to determine the epidemiological features of the brain and central nervous system cancer in the Middle East and North Africa (MENA) region. Methods: In this study, data of the Global Burden of Disease (GBD) study were used to estimate the incidence, prevalence, deaths, disability-adjusted life years (DALYs), and mortality in 21 countries in the MENA region from 1990 to 2019 based on age and sex. The percentage of the changes of epidemiologic indicators was calculated between 1990 and 2019. Results: Palestine and Turkey had the highest rate of brain and central nervous system cancer in 2019. Saudi Arabia, Oman, Iraq, and Lebanon had the highest percentage of incidence rate changes from 1990 to 2019. The prevalence of brain and central nervous system cancer in the MENA region was increased from 7.51 (95% CI: 4.95–11.01) in 1990 to 16.45 (95% CI: 10.83–19.54) in 2019 (percentage of changes = 54.35%). ...
Biomedical Research, 2018
Background: Brain tumors are associated with marked disability and mortality. Understanding the patterns and epidemiological characteristics associated with brain tumors can be crucial to their treatment. Objective: To explore the magnitude and epidemiological features of primary brain tumors among patients admitted to Aseer Central Hospital (ACH), Abha City, Saudi Arabia, and to identify different decisions for their management. Methodology: All hospital records of brain tumor patients admitted to ACH from 2015-2017 were reviewed. Collected data included patients' demographic characteristics, clinical findings, histopathological diagnosis, and management. Results: During the aforementioned period, a total of 100 patients with primary brain tumors were admitted to ACH. The most commonly presenting symptoms were headache (72%), vomiting, dizziness, and focal motor deficits (25% for all). Tumor location was mostly at the frontal or parietal lobes. Among those who underwent surgery, meningioma grade I was the most frequently diagnosed (41.7%). The mean surgical time was 4.2 ± 1.6 h. Most patients who underwent surgery at ACH stayed in the intensive care unit anywhere from 1 d or 2-4 d (34% and 40%, respectively). The Glasgow outcome scale scores of most patients (91.7%) indicated that the patients had a good recovery. However, one patient died (1.7%), one was in a persistent vegetative state (1.7%), and three sustained moderate disability (5%). Conclusion: Most patients with brain tumors admitted to ACH undergo surgery. Meningioma grade I is the most commonly encountered brain tumor, and this finding may reflect different epidemiological findings from the internationally accepted concept that glioblastoma multiforme is the most common brain tumor. The most common locations for brain tumors are the frontal and parietal lobes.
Archives of Pharmacy Practice, 2024
This retrospective study comprehensively analyses the epidemiological trends of Central Nervous System (CNS) cancers in Saudi Arabia over three decades, from 1990 to 2019. Utilizing data from the Institute for Health Metrics and Evaluation (IHME) and the Saudi Cancer Registry, the study examines incidence, prevalence, and mortality rates, offering a detailed depiction of CNS cancer trends in the region. The findings reveal a significant increase in the incidence of CNS cancers, with rates increasing from 1.1 to 3.63 per 100,000 population. Despite this rise, the incidence in Saudi Arabia remains lower than in more developed regions, suggesting regional variations in risk factors and healthcare practices. The study observes a marked decline in mortality rates, from 25% in 1990 to below 10% in 2019, indicative of the effect of advancements in early detection, molecular diagnostics, and therapeutic interventions. Gender disparities were apparent, with males exhibiting higher incidence and mortality rates, aligning with global epidemiological patterns. The study also highlights demographic variability in CNS cancer incidence, with a prominent increase in adult populations, particularly those aged 55 and above. These findings underscore the need for targeted public health strategies and healthcare policies to address the rising incidence and improve patient outcomes. The study advocates for future research focusing on the etiology of CNS cancers, particularly in genetic and environmental factors, and calls for international collaboration in research to understand global variations in CNS cancer trends.
Objectives: to describe the pattern of metastatic brain tumors (MBT) at King Abdulaziz University Hospital (KAUH) over the 6 years and Correlate the clinical data and treatment options with the survival rate. Design: retrospective study. Results: 66 patients were reviewed. Overall, the most common MBT was bronchogenic carcinoma. The mean age was 57.7±15.7 years. The survival was affected negatively in correlation with tumor multiplicity (P <.014), numbness (P <.0001), abnormal vision (P <.001) and seizure (P <.00005). The survival was improved by radiotherapy alone (P <.001). Conclusions: Several clinical risk factors may affect the survival of MBT patients.
2021
OBJECTIVES Central nervous system (CNS) tumors are a major and growing global healthcare challenge. Western Saudi Arabia has an inconsistent data registry; therefore, the epidemiology of CNS tumors is unclear across the country. This study is aimed to assemble the epidemiological matrix of CNS tumors in the Western Province of Saudi Arabia. METHODS A retrospective analysis was performed using clinical data obtained from 3 neuroscience centers in Western Saudi Arabia in the period 2014-2019. The sample size included 663 adult and pediatric cases from the local and expatriate populations diagnosed with CNS tumors. The distributions of age, sex, clinical presentation, tumor location, type of surgery, histological subtype, genetic characteristics, and recurrence rate were explored. RESULTS The analysis included 500 adult cases and 163 pediatric cases up to 18 years of age with a male-to-female ratio of 1.16. The mean age at diagnosis was 38.0±22.6 years. The supratentorium was the most ...
Glioma epidemiology in the central Tunisian population: 1993-2012
Asian Pacific journal of cancer prevention : APJCP, 2014
Glioma is a heterogeneous central nervous system (CNS) tumor group that encompasses different histological subtypes with high variability in prognosis. The lesions account for almost 80% of primary malignant brain tumors. The aim of this study is to extend our understanding of the glioma epidemiology in the central Tunisian region. We analyzed 393 gliomas recorded in cancer registry of central Tunisia from 1993 to 2012. Crude incidence rates (CR) and world age-standardized rates (ASR) were estimated using annual population data size and age structure. Statistic correlations were established using Chi-square and Kaplan-Meier test. Tunisian glioma patients were identified with a mean age at diagnosis of 48 years and 1.5 sex ratio (male/female). During the 19 years period of study the highest incidence value was observed in male group between 1998 and 2002 (CR: 0.28, ASR: 0.3). Incidence results underline increasing high grade glioma occurring in the adulthood in the last period (2007-...
2020
with a diagnosis of primary CNS tumor (brain and spinal cord) were selected. Data about sex, age, tumor location, and histologic type were collected. The classification was based on the International Classification of Diseases for Oncology, 3rd Edition (ICD-O-3). Results. Nine hundred and ninety-two (992) cases of primary CNS tumors throughout the ten years (2005 to 2014) were reviewed. There were 714 (71.97%) adults and 278 (28.02%) in the pediatric age group. Nonmalignant tumors dominated the adult population (60.08%) while malignant tumors were more frequent in the pediatric population. Gliomas constituted the most common neoplastic category in children and adults. The most common single tumor entity was meningioma (26.99%, ICD-O-3 histology codes 9530/0, 9539/1, and 9530/3). Medulloblastomas (ICD-O-3 histology codes 9470, 9471, and 9474) were the most common single tumor entity in the pediatric age group (26.62%). Conclusions. This is an institution-based, detailed, and descriptive epidemiological study of patients with primary CNS tumors in Saudi Arabia. In contrast to other regional and international studies, the medulloblastomas in our institution are more frequent than pilocytic astrocytomas. Limitations to our study included the referral bias and histology-based methodology.
Journal of Neuro-Oncology
Purpose There is large variability in reported incidence rates of primary brain/CNS tumors across the world, with mostly higher rates in higher-income countries. The aim was to compare malignant and benign brain/CNS tumor incidence between Zurich (Switzerland), a high-income country, and Georgia, a lower middle-income country. Methods For the period March 2009 to February 2012, we extracted the following tumors based on topography according to ICD-O3: C70.0–C72.9, and C75.1 (pituitary gland). Data were categorized into histology groups based on the WHO 2007 histological classification. Age-standardized rates per 100,000 person-years were calculated by subgroups. Results We included 1104 and 1476 cases of primary brain/CNS tumors for Zurich and Georgia, respectively. Mean age of patients was significantly lower in Georgia compared to Zurich (50.0 versus 58.3 years). Overall age-standardized incidence rates for malignant and benign brain/CNS tumors were 10.5 (95% CI 9.9–11.0) for Geor...