Impact of the Coronavirus Infection in Pregnancy: A Preliminary Study of 141 Patients (original) (raw)
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COVID-19 infection during pregnancy - maternal and perinatal outcomes: a tertiary care centre study
International Journal of Reproduction, Contraception, Obstetrics and Gynecology
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Pregnancy outcomes with coronavirus pregnancy outcomes with coronavirus infection (COVID-19)
Acta Facultatis Medicae Naissensis
Introduction: The clinical therapy of COVID-19 infection during pregnancy is still insufficient and limited. The current literature on COVID-19 infection during pregnancy and childbirth is summarized in this article, with a focus on maternal and neonatal outcomes. Material and methods: From June 1 to September 7, 2020, a systematic search of pertinent medical subject heading (MeSH) terms, covered by the electronic databases Web of Science and Scopus, PubMed, Google Scholar, and SID key phrases including coronavirus or COVID-19 and pregnancy was undertaken. The search and selection criteria were restricted to English and Farsi literature. COVID-19 in pregnancy articles of all types were considered in the study. The references of relevant studies were also searched. After deleting duplicate and ineligible items, a total of 21 articles were collected. Result: We found 21 studies with a total of 6,569 pregnant women who had COVID-19 infection: only one publication provided disease sever...
COVID-19 Infection in Pregnancy: A Descriptive Cross-sectional Study
Birat Journal of Health Sciences
Introduction: There is diverse evidence regarding the maternal and fetal effect of coronavirus disease 2019 (COVID-19) in pregnancy. Objectives: The objective of this study was to assess the effect of COVID-19 in mother and fetus during pregnancy. Methodology: A descriptive cross-sectional study was conducted during the second wave of COVID-19 in the Department of Obstetrics and Gynaecology at Birat Medical College Teaching Hospital from April 3 to July 3, 2021. All pregnant women admitted in the antenatal ward were sent real-time reverse transcription polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patients with RT-PCR confirmed SARS-CoV-2 infection were enrolled in the study and followed up until discharged. Results: The COVID-19 positivity rate was 18.0%.The mean age was 24.38 years. Majority of the patients were asymptomatic (79.7%) Among symptomatic patients, 73.3% had fever and respiratory symptoms and 95.9% of...
Maternal and neonatal outcome in COVID-19 infection - A tertiary care centre study
Indian Journal of Obstetrics and Gynecology Research, 2022
With exponential increase in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV- 2/COVID-19) worldwide Pregnant women and their fetuses are more susceptible to infection and poor outcomes. The risks to the mother appear to increase during the last trimester. The aim of this study was to summarize the maternal and neonatal outcomes of pregnant women infected with COVID-19 during labour.Eligibility criteria includes pregnant women positive for COVID-19 during the time of labour as detected by real-time polymerase chain reaction (PCR) or dual fluorescence PCR-confirmed SARS-CoV-2 infection.A total of 30 pregnant women positive for COVID-19 as confirmed by RT-PCR, were included in the study. 14 cases (46.6%) had preterm deliveries and LSCS was the preferred mode of delivery in 12 of 30 i.e., 40% cases. There was a tendency for low Apgar score at birth, higher rates of IUD, fetal distress, NICU admissions. There was 5 IUD and one neonatal death. This study confirms that COVID-...
Vaccines
The effects of coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 on pregnant women and neonates are mainly unknown, since limited data are available in the literature. We conducted a monocentric and cross-sectional study enrolling 122 un-vaccinated pregnant women with COVID-19 infection tested by RT-PCR nasopharyngeal swab. Only 4.1% of the patients had severe COVID-19 symptoms together with major respiratory symptoms and intensive care unit admission, whereas 35.25% of women had comorbidities and two-thirds of them were overweight or obese. COVID-19 was detected mainly in the third trimester (98.36%) and multiparous women (59.02%). The mode of delivery was influenced by mild–severe COVID-19 symptoms, with a higher number of urgent or emergent cesarean sections than spontaneous or operative vaginal births. Preterm births were associated with high BMI, mode of delivery (higher among cesarean sections), nulliparity, and severe COVID-19 symptoms. In cas...
Midwifery, 2021
Objective Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has caused many deaths and complications worldwide. However, limited data are available about COVID-19 during pregnancy. This study aimed to assess the epidemiological and clinical features of COVID-19, and the adverse maternal and fetal outcomes. Design This retrospective analytical cohort study was conducted on all pregnant women with confirmed COVID-19 at Nekouei-Hedayati-Forghani Hospital in Qom, Iran from 1 February 2019 to 15 September 2020. For the same period, 165 pregnant women who did not have COVID-19 were selected at random and included in this study. All epidemiological and clinical features were collected from the medical records of the participants. A logistic regression model was used to determine associations between COVID-19 in pregnancy and maternal and fetal outcomes. Findings The most common symptoms reported by pregnant women with COVID-19 were...
Risks of Novel Coronavirus Disease (COVID-19) in Pregnancy; a Narrative Review
Archives of Academic Emergency Medicine, 2020
Introduction: The outbreak of the new Coronavirus in China in December 2019 and subsequently in various countries around the world has raised concerns about the possibility of vertical transmission of the virus from mother to fetus. The present study aimed to review published literature in this regard. Methods: In this narrative review, were searched for all articles published in various databases including PubMed, Scopus, Embase, Science Direct, and Web of Science using MeSH-compliant keywords including COVID-19, Pregnancy, Vertical transmission, Coronavirus 2019, SARS-CoV-2 and 2019-nCoV from December 2019 to March 18, 2020 and reviewed them. All type of articles published about COVID-19 and vertical transmission in pregnancy were included. Results: A review of 13 final articles published in this area revealed that COVID-19 can cause fetal distress, miscarriage, respiratory distress and preterm delivery in pregnant women but does not infect newborns. There has been no report of ve...
The effect of COVID-19 on maternal and neonatal outcome - A retrospective study
2021
The pandemic of coronavirus disease (COVID-19) has caused serious adverse effects on the human race. There are limited data on maternal and neonatal outcomes of pregnant women with COVID-19. Materials and Methods: An observational descriptive study was conducted in the department of obstetrics & gynaecology at SMSR and Sharda hospital located in Greater Noida, Uttar Pradesh. This medical college drains patients from entire Greater Noida and as well as from faraway places as referrals. All pregnant patients were included that came to this hospital from 1 s t April to 31 s t May 2021. These were the two dreadful months for the entire country in which so many lives were lost. All pregnant patients were labelled COVID-19 positive after undergoing either Rapid antigen test/RTPCR test taken from nasopharyngeal and oral swab. Aims & Objectives: This included assessment of the maternal morbidity and mortality, comorbidities & worsening of outcome due to COVID-19 infection in pregnant patients as well assessment of the effect of COVID-19 infection on fetus and newborn. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Impact of COVID-19 on Pregnancy and Maternal Health: An Update
Biomedical Research and Therapy, 2021
The current pandemic caused by the novel coronavirus disease 2019 (COVID-19) is spreading at an accelerated rate globally. Global concerns were raised following its discovery in December 2019, as previous similar diseases. Diseases such as the severe acute respiratory syndrome-related coronavirus (SARS-CoV) and the Middle East respiratory syndrome-related coronavirus (MERS-CoV) are known to lead to adverse outcomes in pregnant women and those in early maternal stages, with significantly higher rates of complication and mortality compared to other groups of individuals. The anatomical, physiological, and immunological changes that occur during pregnancy lead to higher risks associated with respiratory infections for pregnant women, as they can directly affect the well-being of pregnant women and infants. Vertical transmission of COVID-19 from mother to child was a concern, as such transmission could endanger a child. Three mechanisms of vertical transmission have been suggested: intrauterine transmission, placental blood transmission, and intrapartum transmission. This review discusses the impact and pathogenicity of COVID-19 on the well-being of pregnant and early maternal women, both the clinical aspect, health aspects, and diagnostic and therapeutic options. It will also discuss the adverse outcomes among pregnant women and newborn infants who contract the disease and the different mechanisms of vertical transmission from infected mother to child. The diagnostic and therapeutic approaches of COVID-19 that have been recently used have also been highlighted, in addition to the challenges faced by pregnant women who have contracted the virus during the pandemic.