The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis (original) (raw)

The Mitochondrial Cardiolipin Remodeling Enzyme Lysocardiolipin Acyltransferase (LYCAT) is a Novel Target in Pulmonary Fibrosis

Imre Noth, Biji Mathew

American Journal of Respiratory and Critical Care Medicine, 2014

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Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis

Divya Bhatia

Nature Communications, 2019

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Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics

Sainath Kotha MD

Journal of Biological Chemistry, 2020

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Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosis

Michael Schuler

Scientific Reports, 2017

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Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage

Raul Piseaux

Free radical biology & medicine, 2016

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Extracellular Mitochondrial DNA is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis

Tony Woolard

American journal of respiratory and critical care medicine, 2017

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Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis

Chun Lee

PLOS ONE, 2015

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Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis

Raul Piseaux

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2020

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Mitochondrial quality control in pulmonary fibrosis

A. Brent Carter

Redox Biology, 2020

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Idiopathic Pulmonary Fibrosis: Let’s Keep the Focus on the A(ge)TII cell

Mareike Lehmann

American Journal of Respiratory and Critical Care Medicine

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LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1

Sheng Xiong

Journal of cell science, 2015

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The Role of Interaction between Mitochondria and the Extracellular Matrix in the Development of Idiopathic Pulmonary Fibrosis

Kamil Siekacz

Oxidative Medicine and Cellular Longevity

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Lysyl Oxidase-like 1 Protein Deficiency Protects Mice from AdTGF-β1 Induced Pulmonary Fibrosis

Chiko Shimbori

American journal of respiratory cell and molecular biology, 2017

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Molecular mechanisms of pulmonary fibrosis

Annie Pardo

Frontiers in Bioscience, 2002

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Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts

Steven Mutsaers

Journal of cellular and molecular medicine, 2018

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PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

Jose Herazo-Maya

Journal of Clinical Investigation, 2014

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Identification of the Human Mitochondrial Linoleoyl-coenzyme A Monolysocardiolipin Acyltransferase (MLCL AT-1)

WILLIAM TAYLOR

Journal of Biological Chemistry, 2009

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Modulation of Oxidative Phosphorylation with IM156 Attenuates Mitochondrial Metabolic Reprogramming and Inhibits Pulmonary Fibrosis

Dean Welsch

Journal of Pharmacology and Experimental Therapeutics, 2021

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Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis

Hằng Phan

Cellular and Molecular Life Sciences

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Unravelling the progressive pathophysiology of idiopathic pulmonary fibrosis

Clemens Ruppert

European respiratory review : an official journal of the European Respiratory Society, 2012

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Differential Lysotracker Uptake Defines Two Populations of Distal Epithelial Cells in Idiopathic Pulmonary Fibrosis

Elie El Agha

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Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis

Ludger Fink, Clemens Ruppert

American Journal of Respiratory and Critical Care Medicine, 2008

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Cysteinyl Leukotrienes in Pulmonary Fibrosis: Modulation of the Functions of Fibrocytes and Fibroblasts

Akiko Maekawa

Journal of Allergy and Clinical Immunology, 2008

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Signaling pathways in the epithelial origins of pulmonary fibrosis

Vrushank Davé

Cell Cycle, 2010

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Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain

Alfiya Bikineyeva

Mitochondrion, 2016

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Serum metabolic profiling identified a distinct metabolic signature in patients with idiopathic pulmonary fibrosis – a potential biomarker role for LysoPC

Nagireddy Putluri

Respiratory Research, 2018

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