Impact of Neoadjuvant Chemotherapy on the Post Mastectomy Quality of Life in Bangladeshi Breast Cancer Patients (original) (raw)
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A study of quality of life among patients undergoing mastectomy for malignant breast lesions
International Surgery Journal, 2017
Background: To evaluate quality of life of females after mastectomy and factors affecting the same, in various domains of life, and to assess whether a policy of mastectomy is practical or pragmatic in the scenario of low socioeconomic status prevalent in our region.Methods: Two hundred and forty post-operative mastectomized patients were clinically examined and subjected to a questionnaire designed by WHOQOL-BREF along with an ethically cleared questionnaire prepared according to the local prevailing conditions and Quality of Life was evaluated.Results: 52% patients reported no change in body image, only 2% patients reported depression. The total score of the quality of life was good for 40% of the patients with score of 96-130, followed by 55% with moderate 61-95 and only 5% patients with poor with score of <60.Conclusions: In developing countries like India where, there are no proper facilities for advanced haematological and radiological investigations, there is a severe lack...
Journal of Applied Pharmaceutical Science, 2016
Breast cancer is the most common cancer among women and an increasingly important issue is to evaluate quality of life (QoL) among these patients. The objective of this study was to appreciate the QoL and associated factors among breast cancer womenundergoing different types of therapy. A cross-sectional study was carried out among 166 breast cancer women from two specialized centres in Baghdad, Iraq, from February 2014 to December 2014. The questionnaire used in this study was "The Functional Assessment of Cancer Therapy-Breast (FACT-B)". The majority were employee (60.3%), with high school education (63.2%), with no family history of cancer (79.5%). Majority were diagnosed with grade II (56.6%) and tumor size less than 2 cm in diameter (95.8%). The majority of women underwent mastectomy (98.2%), received chemotherapy, radiotherapy, and Tamoxifen therapy (89.8%, 29.5%, and 36.1%; respectively).The study found a significant difference between the quality of life among cancer patients and job, stage of cancer, size of tumor, and radiotherapy. Job, stage of cancer, size of tumor, and radiotherapy significantly influenced the women QoL. Therefore, more attention on these variables is highly recommended when dealing with breast cancer patients undergoing different types of therapy.
Indonesian Journal of Cancer, 2021
Background: The quality of life (QoL) of breast cancer (BCa) patients is an outcome of therapy that is often overlooked. In real life, postoperative breast cancer patients experience deep trauma in view that breasts are a symbol of femininity, which are very valuable for any female. This study aims to compare the QoL in patients who received mastectomy only and mastectomy with reconstruction.Methods: A retrospective comparative study of 25 post-mastectomy to 25 post-mastectomy with reconstruction BCa patients in Onkologi Surabaya Hospital. The subjects are patients who visited between July 2019 until March 2020, as many as 50 samples in accord with the inclusion and exclusion criteria. The assessment was performed using 3 instruments, including the hospital anxiety and depression scale (HADS), body image scale (BIS), and female sexual function index (FSFI). The collected data were analyzed using SPSS 15.0 for Windows.Results: A significant difference in mean values was seen in body ...
Asian Pacific Journal of Cancer Prevention, 2014
The aim of this study was to investigate the differences in quality of life in patients who received breast conserving surgery (BCS) or modified radical mastectomy (MRM) for breast cancer. Materials and Methods: A total of 100 women with breast cancer who underwent either BCS or MRM between September 2011 and April 2012 at a private health center and completed their chemotherapy and radiation therapy cycles were included in the study. To assess the quality of life, we used a demographic questionnaire, the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and the Quality of Life assessment in Breast Cancer (EORTC QLQ-BR23). Results: Using QLQ-C30, we found that patients who underwent BCS had better functional status and fewer symptoms than patients who underwent MRM. In QLQ-BR23, independent factors improving the functional scales were BCS, higher level of education and marital status (married); independent factors improving symptoms were BCS, higher level of education, younger age and low and normal body mass index (BMI). In QLQ-C30, independent factors affecting the functional and symptom scales were only BCS and higher level of education. Conclusions: We determined that patients who received BCS had better functional status and less frequent symptoms than patients who underwent MRM.
Quality of life and related factors among the women undergoing mastectomy
Iranian journal of nursing and midwifery research
Breast cancer is the most common cancer among women and 81% of therapeutic surgery performed for breast cancer in Iran is mastectomy. Following mastectomy, the patients suffer from many problems which lead to several disorders and decrease in their quality of life (QOL). This cross-sectional descriptive study was conducted on 105 breast cancer patients who underwent mastectomy, selected with a convenient sampling method. A questionnaire containing three parts was used to collect data. The data were analyzed by SPSS version 14 using descriptive and analytical statistical methods. Spearman test showed that there was a statistically significant relationship between QOL and education level and also fatigue. Moreover, Spearman test indicated a statistically significant correlation between age and the mental dimension of QOL. There was no significant relationship between QOL with marital and employment status. Based on the findings, we can suggest that nurses should be educated about the ...
ASSESSMENT OF QUALITY OF LIFE IN BREAST CANCER PATIENTS: A RETROSPECTIVE COHORT STUDY
In India the Breast cancer is the most common type of cancer in women. The patients with breast cancer were facing many problems neither by the disease nor by the treatment side effects. So that measuring quality of life in patients with breast cancer is important for assessing the treatment outcomes. Thus in our study we analysed the impact of treatment on quality of life of women with breast cancer. The purpose of present study is to assess the quality of life in breast cancer patients to manage their treatment and to prevent further progression of disease.
PLOS ONE, 2019
This cross-sectional study is aimed at assessing the quality of life in a cohort of breast cancer patients at the Oncology Department, King Abdulaziz University Hospital (KAUH), King Abdulaziz University (KAU), Jeddah, Saudi Arabia (SA), and to differentiate QoL among different groups. Mean time since diagnosis was 3.97±1.90 years. European Organization for Research and Treatment of Cancer Quality of Life Questionnaires-Core30 and BR23 (EORTC QLQ-C30 & BR23) were used to assess QoL in breast cancer survivors. ANOVA and independent t-test (parametric tests) were used for the categorical variables and Kruskal-Wallis and Mann-Whitney tests used for non-parametric tests. Linear regression analysis was done to measure predictors' significance and to calculate the coefficient of determination. Two hundred and eighty-four patients completed the survey. Global health status and functional scales, in most of the domains, were high, while symptom scales were moderate-to-low for most items, showing better QoL. Insomnia and fatigue were the most disturbing symptoms. Patients exhibited higher scores for body image and future perspective, while the least score is for sexual functioning. Global health, physical functioning, and role functioning were better in the age group �50 years (p<0.05). Premenopausal and perimenopausal patients showed a better level of functioning as compared to postmenopausal patients (p = 0.001). Premenopausal patients scored higher for sexual enjoyment, as compared to peri-and postmenopausal patients (p = 0.04). Systemic therapy side effects were more evident in the breast conservative surgery group. Predictors explained 8% of the variation in Physical functioning (R-squared = 0.08). A predictor that had a remarkable influence on physical functioning, as compared to the other predictors in the model, was menopausal status (P = 0.02). So, it was concluded that the breast cancer patients visiting our institute had a better quality of life regarding overall global health status as well as functional and symptom scales. Some issues, for instance, fatigue, insomnia, hair loss, and others, warrant good supportive therapy.
Quality of Life Research
Purpose Breast cancer is the commonest cancer in women worldwide. Surgery is a central part of the treatment. Modified radical mastectomy (MRM) is often replaced by breast conserving therapy (BCT) in high-income countries. MRM is still the standard choice, in low- and middle-income countries (LMICs) as radiotherapy, a mandatory component of BCT is not widely available. It is important to understand whether quality of life (QOL) after MRM is comparable to that after BCT. This has not been studied well in LMICs. We present, 5-year follow-up of QOL scores in breast cancer patients from India. Methods We interviewed women undergoing breast cancer surgery preoperatively, at 6 months after surgery, and at 1 year and 5 years, postoperatively. QOL scores were evaluated using FACT B questionnaire. Average QOL scores of women undergoing BCT were compared with those undergoing MRM. Total scores, domain scores and trends of scores over time were analyzed. Results We interviewed 54 women with a ...
Assessment of quality of life of breast cancer patients attending a tertiary hospital in Bangladesh
ObjectiveBreast cancer is the most commonly diagnosed malignancy and a leading cause of death among women. This cross-sectional study assessed the quality of life (QOL) of breast cancer patients attending a tertiary hospital in Dhaka, Bangladesh.MethodData were obtained from 359 female breast cancer patients at a tertiary hospital between November 23 and December 9, 2019, using a digital platform (Kobo Toolbox). A Bangla translation of the QOL questionnaire (EORTC-QLQ-C30) was used to assess QOL. The survey comprised three scales: global health, functional, and symptoms scale. For the functional and global health scales, we adopted a cut-off level of ≥66% score for good QOL and ≤33% for poor QOL, which was reversed for the symptoms scale. Using STATA 13.0, we performed descriptive and logistic regression analyses.ResultAmong the 359 patients, 86.35% were housewives, and 50.42% of them came from the Dhaka division. In contrast to the 38.44% and 42.90 % of respondents who scored highl...