Modulatory role of vanadium on trace element profile in diethylnitrosamine-induced rat hepatocarcinogenesis (original) (raw)

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2000

Abstract

Particle-induced X-ray emission (PIXE) analysis was employed in the present study to investigate the chemopreventive potential of vanadium in influencing trace elemental profile and antioxidant status in chemical carcinogenesis. The elements with Z=15–40 were studied. Data reveal remarkable alterations in elemental composition in the hepatic tissue of diethylnitrosamine (DENA)-induced Sprague–Dawley male rats (intraperitoneal (ip) dose: 200 mg/kg body weight) after

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