P07.01: Artificial intelligence (AI) weights the importance of clinical and sonographic factors predicting malignancy in unilocular‐solid cysts before surgery (original) (raw)

Doppler assessment during their routine 20 weeks anomaly scan. UtA Doppler was considered abnormal if sum of pulsatility index (PI) of both uterine arteries was ≥ 2.5. Women were assigned to 4 risk group categories according with presence of SGA maternal risk factors and UtA results: A. low risk: no risk factors and normal UtA; B. intermediate-low risk: no risk factors and abnormal UtA; C. intermediate-high risk: risk factors present and normal UtA; D. high risk: risk factors present and abnormal UtA. The primary outcome was SGA, defined as a baby with birth weight < 10 th centile according with INTERGROWTH-21st standards. Sensitivity and specificity were calculated. Results: UtA Doppler assessment and birth weight were available in 864 women. Amongst those women, neonatal SGA occurred in 51 (5.90%), UtA was abnormal in 91% of all cases. The overall sensitivity, specificity, positive and negative predictive value were, 33, 88, 16, and 95%, respectively. In the low and intermediate-low risk group sensitivity and negative predictive value were similar to the all population (33, and 96%, respectively) (group A and B). SGA rate detection in the intermediate-low risk group doubled (from 8 to 16 cases). In the intermediate-high and high risk groups (C, D), sensitivity was higher (58%); with a lower negative predictive value (91%). Conclusions: UtA Doppler assessment in the second trimester, as a part of a multiparamenter test for screening for SGA, improves detection rate, especially in the subgroup of patients with risk factors for SGA. Negative predictive value in low-risk women can justify its use routinely.