original ) (raw )STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy
Valeria Poli
EMBO Molecular Medicine, 2013
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Many good reasons to have STAT3 in the heart
Andres Hilfiker
Pharmacology & Therapeutics, 2005
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STAT3, a key regulator of cell-to-cell communication in the heart
Denise Hilfiker-kleiner
Cardiovascular Research, 2014
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Differential STAT3 signaling in the heart
Fouad Zouein
JAK-STAT, 2012
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Pivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved Issues
Edward Lesnefsky
Frontiers in Cardiovascular Medicine, 2015
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STAT3 and cardiac remodeling
Denise Hilfiker-kleiner
Heart Failure Reviews, 2010
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Effects of Cardiovascular Risk Factors on Cardiac STAT3
Márta Sárközy
International Journal of Molecular Sciences
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STAT3 deletion sensitizes cells to oxidative stress
Justin McCormick
Biochemical and Biophysical Research Communications, 2009
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The C-terminal activation domain of the STAT-1 transcription enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes
Paul Townsend
The FASEB Journal, 2002
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Protective Function of STAT3 in CVB3-Induced Myocarditis
Denise Hilfiker-kleiner
Cardiology Research and Practice, 2012
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Ischemia-induced STAT-1 Expression and Activation Play a Critical Role in Cardiomyocyte Apoptosis
Anne K Jonassen
Journal of Biological Chemistry, 2000
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Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart.
Saiful Anam Mir
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Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts
Dominic Ng
Cardiovascular research, 2003
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Regulation of Myocardial Interleukin-6 Expression by p53 and STAT1
Paul Townsend
Journal of Interferon & Cytokine Research, 2013
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Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy
Anne Roivainen
European heart journal, 2016
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Cardiopulmonary Bypass Decreases Activation of the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway in Diabetic Human Myocardium
Frank Sellke
The Annals of Thoracic Surgery, 2015
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Rapid communication Genetic depletion of cardiac myocyte STAT3 abolishes classical preconditioning
Lydia Lacerda
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Innate Defense Mechanism Against Virus Infection Within the Cardiac Myocyte Requiring gp130-STAT3 Signaling
D. Summers-torres
Circulation, 2006
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Continuous Glycoprotein-130-Mediated Signal Transducer and Activator of Transcription-3 Activation Promotes Inflammation, Left Ventricular Rupture, and Adverse Outcome in Subacute Myocardial Infarction
Denise Hilfiker-kleiner
Circulation, 2010
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Genetic depletion of cardiac myocyte STAT3 abolishes classical preconditioning
Lydia Lacerda
Cardiovascular Research, 2004
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Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function
Pasquale Pagliaro
Basic Research in Cardiology
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Induction of high STAT1 expression in transgenic mice with LQTS and heart failure
Teng Zhang
Biochemical and Biophysical Research Communications, 2007
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H11 Kinase/Heat Shock Protein 22 Deletion Impairs Both Nuclear and Mitochondrial Functions of STAT3 and Accelerates the Transition Into Heart Failure on Cardiac OverloadClinical Perspective
Didier Morin
2011
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p42/p44-MAPK and PI3K are sufficient for IL-6 family cytokines/gp130 to signal to hypertrophy and survival in cardiomyocytes in the absence of JAK/STAT activation
Nicola Smart
Cellular Signalling, 2013
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Signal Transducer and Activator of Transcription 3 Is Required for Myocardial Capillary Growth, Control of Interstitial Matrix Deposition, and Heart Protection From Ischemic Injury
Millet E , Andres Hilfiker
2000
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Augmented Expression of Cardiotrophin-1 in Failing Human Hearts Is Accompanied by Diminished Glycoprotein 130 Receptor Protein Abundance
Leong Loke Ng
Circulation, 2002
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Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
Werner Müller
Cell, 1999
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IL 10 Treatment Attenuates Pressure Overload-Induced Hypertrophic Remodeling and Improves Heart Function via STAT3 Dependent Inhibition of NFκB
Suresh Verma
Circulation, 2012
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The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis
Sarin Somers
Cardiovascular Research, 2008
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Targeting Mediators of Inflammation in Heart Failure: A Short Synthesis of Experimental and Clinical Results
Attila Frigy
International Journal of Molecular Sciences
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Cardioprotection by Ischemic Postconditioning Is Lost in Aged and STAT3-Deficient Mice
Bernd Ebner
Circulation Research, 2008
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Roles of STATs signaling in cardiovascular diseases
Suresh Verma
JAK-STAT, 2012
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