Evidence for the Involvement of Cytosolic 5′-Nucleotidase (cN-II) in the Synthesis of Guanine Nucleotides from Xanthosine (original) (raw)
Substrates and/or Inhibitors of IMP-GMP Specific Cytosolic 5′-Nucleotidase (cN-II)
Rossana Pesi
Expert Opinion on Therapeutic Targets, 1997
View PDFchevron_right
Modulation of IMP dehydrogenase activity and guanylate metabolism by tiazofurin
Mary Faderan
Journal of Biological Chemistry
View PDFchevron_right
Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the antiviral nucleoside 2′,3′-dideoxyguanosine
Gurpreet Ahluwalia
Biochemical and Biophysical Research Communications, 1990
View PDFchevron_right
Recent advances in structure and function of cytosolic IMP-GMP specific 5′nucleotidase II (cN-II)
Maria Grazia Tozzi
Purinergic Signalling, 2006
View PDFchevron_right
IMP - GMP specific cytosolic 5'-nucleotidase regulates nucleotide pool and prodrug metabolism
Federico Cividini, Pesi Rossana, Simone Allegrini, Marcella Camici
Biochimica et biophysica acta, 2015
View PDFchevron_right
Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase
Victor Marquez
International Journal of Cancer, 1994
View PDFchevron_right
The course analysis of guanine and hypoxanthine transformation to uric acid by bovine liver guanine aminihydrolase and xanthine oxidase
Enric I. Canela
Journal of Molecular Catalysis, 1981
View PDFchevron_right
Discovery of N-[2-[2-[[3-Methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a Novel and Potent Inhibitor of Inosine Monophosphate Dehydrogenase with Excellent in Vivo Activity
ganga dhar
Journal of Medicinal Chemistry, 2002
View PDFchevron_right
Rod and Ring formation from IMP dehydrogenase is regulated via the one-carbon metabolic pathway
Dania Saleem
Journal of cell science, 2016
View PDFchevron_right
Cofactor Mimics as Selective Inhibitors of NAD-dependent Inosine Monophospate Dehydrogenase (IMPDH) - the Major Therapeutic Target
Dipesh Risal
Current Medicinal Chemistry, 2004
View PDFchevron_right
Inactivation of hypoxanthine guanine phosphoribosyltransferase by guanosine dialdehyde: An active site directed inhibitor
Lambro Johnson
Biochemical Medicine, 1979
View PDFchevron_right
Human IMP dehydrogenase:: Kinetics and regulatory properties
Mike P.
Biochimica et Biophysica Acta (BBA) …, 1974
View PDFchevron_right
Increased activity, amount, and altered kinetic properties of IMP dehydrogenase from mycophenolic acid-resistant neuroblastoma cells
Bernard Renaux
Journal of Biological Chemistry
View PDFchevron_right
Inhibition of two enzymes in de novo purine nucleotide synthesis by triciribine phosphate (TCN-P)
Stephen Massia
Biochemical Pharmacology, 1989
View PDFchevron_right
IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma
Nobuyuki Onishi
Nature Cell Biology, 2019
View PDFchevron_right
The Purine analog fludarabine acts as a cytosolic 5′-nucleotidase II inhibitor
Maria Grazia Tozzi
Biochemical Pharmacology, 2015
View PDFchevron_right
Cytosolic purine 5′-nucleotidases of rat liver and human red blood cells: Regulatory properties and role in AMP dephosphorylation
Françoise Bontemps
Advances in Enzyme Regulation, 1988
View PDFchevron_right
Interaction among the distinct effects of adenine and guanine depletion in mouse lymphoma cells
Binh Nguyen
Cancer research, 1984
View PDFchevron_right
Stimulation by Glycerate 2,3-Bisphosphate: A Common Property of Cytosolic Purine 5′-Nucleotidase in Various Tissues
Françoise Bontemps
Springer eBooks, 1989
View PDFchevron_right
Regulation of the Interaction of Inosine Monophosphate Dehydrogenase with Mycophenolic Acid by GTP
Alexander Makhov
Journal of Biological Chemistry, 2006
View PDFchevron_right
Inhibition of 5,10-methylenetetrahydrofolate dehydrogenase by purine nucleotides
Fram Dalal
Biochemical and Biophysical Research Communications, 1966
View PDFchevron_right
Structure and Mechanism of Inosine Monophosphate Dehydrogenase in Complex with the Immunosuppressant Mycophenolic Acid
Mark Murcko
Cell, 1996
View PDFchevron_right
Two distinct cDNAs for human IMP dehydrogenase
Shigeo Ohno
The Journal of biological chemistry, 1990
View PDFchevron_right
Guanine nucleotides protect adenylate cyclase against inhibition by Pb2+
Stein Doskeland
Biochimica et Biophysica Acta (BBA) - General Subjects, 1980
View PDFchevron_right
Metabolic fate of AMP, IMP, GMP and XMP in the cytosol of rat brain: an experimental and theoretical analysis: Nucleotide metabolism in rat brain cytosol
amparo torrecilla
Journal of Neurochemistry, 2001
View PDFchevron_right
Hypoxanthine Guanine Phosphoribosyltransferase Distorts the Purine Ring of Nucleotide Substrates and Perturbs the p K a of Bound Xanthosine Monophosphate
Mrinalini Puranik
Biochemistry, 2011
View PDFchevron_right
Nucleoside phosphotransferase activity of human colon carcinoma cytosolic 5′-nucleotidase
S. Allegrini
Archives of Biochemistry and Biophysics, 1991
View PDFchevron_right
Role of Human Nucleoside Transporters in the Cellular Uptake of Two Inhibitors of IMP Dehydrogenase, Tiazofurin and Benzamide Riboside
Vijaya Damaraju
Molecular Pharmacology, 2005
View PDFchevron_right
Metabolism of Guanine and Guanine Nucleotides in Primary Rat Neuronal Cultures
Yechezkel Sidi
Journal of Neurochemistry, 1992
View PDFchevron_right
Active and regulatory sites of cytosolic 5′-nucleotidase
Simone Allegrini, Marcella Camici
FEBS Journal, 2010
View PDFchevron_right
Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5′-triphosphates, nucleoside 5′-[γ-thio]triphosphates and nucleoside 5′-[β,γ-imido]triphosphates
Gerald Lushington
Biochemical Pharmacology, 2005
View PDFchevron_right
Nucleotide metabolism
Sameh Rizk
View PDFchevron_right
Nucleoside and nucleotide modulation of genetic expression — A new approach to chemotherapy
Ganapathi Revankar
Advances in Enzyme Regulation, 1989
View PDFchevron_right