Eukaryotic translation initiation is controlled by cooperativity effects within ternary complexes of 4E-BP1, eIF4E, and the mRNA 5′ cap (original ) (raw )A Quantitative Molecular Model for Modulation of Mammalian Translation by the eIF4E-binding Protein 1
Muhammad Romdhonul Karim
Journal of Biological Chemistry, 2001
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A fluorescence spectroscopic study on the binding of mRNA 5′-cap-analogs to human translation initiation factor eIF4E: a critical evaluation of the sources of error
Zbigniew Wieczorek
Journal of Photochemistry and Photobiology B: Biology, 1998
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Small-Molecule Inhibition of the Interaction Between the Translation Initiation Factors EIF4E and EIF4G
Nathan Moerke
Cell, 2007
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The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins
Arnim Pause
Molecular and cellular biology, 1995
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The eukaryotic translation initiation factor eIF4E wears a “cap” for many occasions
Katherine Borden
Translation, 2016
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Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation
Nahum Sonenberg
The EMBO Journal, 1994
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Structural Studies on the eIF4A-eIF4G Interaction in Translation Initiation
Katherine Edmonds
2012
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The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation
Cátia Igreja
Molecular cell, 2016
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Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
Haribabu Arthanari , Evangelos Papadopoulos , Ricard Rodriguez-Mias
Proceedings of the National Academy of Sciences, 2014
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Requirement of RNA Binding of Mammalian Eukaryotic Translation Initiation Factor 4GI (eIF4GI) for Efficient Interaction of eIF4E with the mRNA Cap
Akiko Yanagiya
Molecular and Cellular Biology, 2009
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Single-Molecule Studies of the Effects of Small Compounds on the Activity of Translation Initiation Factor eIF4A
Amit Meller
Biophysical Journal, 2011
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Eukaryotic Translation Initiation Factor 4E (eIF4E) Binding Site and the Middle One-Third of eIF4GI Constitute the Core Domain for Cap-Dependent Translation, and the C-Terminal One-Third Functions as a Modulatory Region
Nahum Sonenberg
Molecular and Cellular Biology, 2000
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In vitro activity of human translation initiation factor eIF4B is not affected by phosphomimetic amino acid substitutions S422D and S422E
Ilya Terenin , Lev Shagam
Biochimie, 2012
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Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit
Korneeva, Nadejda , Christopher Bradley , Robert Rhoads
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Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F
Regina Cencic
Proceedings of the National Academy of Sciences, 2011
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Dominant negative mutants of mammalian eIF-4A define a critical role for eIF-4F in cap-dependent initiation of translation
Arnim Pause
The EMBO Journal
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Alterations in interprotein interactions between translation initiation factors assessed by fluorescence resonance energy transfer
Scot Kimball
The International Journal of Biochemistry & Cell Biology, 2001
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Phosphorylation of the Eukaryotic Translation Initiation Factor eIF4E Contributes to Its Transformation and mRNA Transport Activities
Ivan Topisirovic
Cancer Research, 2004
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A Conserved HEAT Domain within eIF4G Directs Assembly of the Translation Initiation Machinery
Nahum Sonenberg
Molecular Cell, 2001
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Sequential Eukaryotic Translation Initiation Factor 5 (eIF5) Binding to the Charged Disordered Segments of eIF4G and eIF2β Stabilizes the 48S Preinitiation Complex and Promotes Its Shift to the Initiation Mode
Hiroyuki Hiraishi
Molecular and Cellular Biology, 2012
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Sequential Eukaryotic Translation Initiation Factor 5 (eIF5) Binding to the Charged Disordered Segments of eIF4G and eIF2 Stabilizes the 48S Preinitiation Complex and Promotes Its Shift to the Initiation Mode
Chingakham Singh
Molecular and Cellular Biology, 2012
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The requirement for eukaryotic initiation factor 4A (eIF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure
Graham Belsham
RNA, 2001
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Translation driven by an eIF4G core domain in vivo
Thomas Preiss
1999
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A New Paradigm for Translational Control: Inhibition via 5′-3′ mRNA Tethering by Bicoid and the eIF4E Cognate 4EHP
Nahum Sonenberg
Cell, 2005
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Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E
Laurent Volpon , Nadeem Siddiqui
Journal of Molecular Biology, 2012
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Translational Homeostasis via the mRNA Cap-Binding Protein, eIF4E
Nahum Sonenberg
Molecular Cell, 2012
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The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled
Katherine Borden
Immunological Reviews, 2014
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Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E
David Cowburn
Proceedings of the National Academy of Sciences, 2010
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The Eukaryotic Initiation Factor (eIF) 4G HEAT Domain Promotes Translation Re-initiation in Yeast Both Dependent on and Independent of eIF4A mRNA Helicase
Stephen Fox
Journal of Biological Chemistry, 2010
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Targeting the eIF4F translation initiation complex for cancer therapy
Nahum Sonenberg
Cell Cycle, 2008
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The translational repressor 4E-BP called to order by eIF4E: new structural insights by SAXS
patrick Cormier
Nucleic Acids Research, 2011
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