Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis (original) (raw)

This review focuses on experimental forms of obesity, particularly those induced by hypothalamic injury and genetic predisposition in rodent models. It critically evaluates recent literature on these forms of obesity, emphasizing the physiological and biochemical mechanisms involved, while providing a framework to integrate new findings. Moreover, it highlights the significant increase in research publications on this topic since the early 1970s, underscoring the need for comprehensive analysis and understanding of emerging obesity models.