Central and Effector Memory CD4 and CD8 T-Cell Responses to Tumor-Associated Antigens (original) (raw)
Tumor-specific CD4 + T cells maintain effector and memory tumor-specific CD8 + T cells
Shawn Jensen
European Journal of Immunology, 2014
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Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
Luca Gattinoni, Paul Andrew Antony, MD
Proceedings of the National Academy of Sciences, 2005
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Vaccine-Induced Effector-Memory CD8+ T Cell Responses Predict Therapeutic Efficacy against Tumors
Cornelis Melief
The Journal of Immunology, 2012
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CD4+ T Cells Are Able to Promote Tumor Growth through Inhibition of Tumor-Specific CD8+ T-Cell Responses in Tumor-Bearing Hosts
Cornelis Melief
Cancer Research, 2005
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Immunotherapy-induced CD8+ T Cells Instigate Immune Suppression in the Tumor
John Hassell
Molecular Therapy, 2014
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Functional differences between low- and high-affinity CD8 + T cells in the tumor environment
Shawn Hartman
OncoImmunology, 2012
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CD4 T cells in tumor immunity
maurizio zanetti
Springer Seminars in Immunopathology, 2005
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Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8(+) T cells
Mariano Esteban
Nature communications, 2017
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Immunotherapy Expands and Maintains the Function of High-Affinity Tumor-Infiltrating CD8 T Cells In Situ
Amy Moran
The Journal of Immunology, 2016
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CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells
Chi-Chao Chan
The Journal of Immunology, 2005
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Antigen-specific CD4+ T-cell help is required to activate a memory CD8+ T cell to a fully functional tumor killer cell
Germain J P Fernando
Cancer research, 2002
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Exhausted CD8+T Cells in the Tumor Immune Microenvironment: New Pathways to Therapy
weixiang zhong
Frontiers in Immunology, 2021
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Helper Function of Memory CD8+ T Cells: Heterologous CD8+ T Cells Support the Induction of Therapeutic Cancer Immunity
Pawel Kalinski, Louis Falo
Cancer Research, 2007
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CD4 T Cells and Their Role in Antitumor Immune Responses
Cornelis Melief
Journal of Experimental Medicine, 1999
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Quiescent phenotype of tumor-specific CD8+ T cells following immunization
Vladia Monsurrò
Blood, 2004
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The function and dysfunction of memory CD8+T cells in tumor immunity
James Reading
Immunological Reviews, 2018
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Phenotype and Homing of CD4 Tumor-Specific T Cells Is Modulated by Tumor Bulk
Anna Mondino
The Journal of Immunology, 2005
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Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression
Ashmitaa Logandha Ramamoorthy Premlal
Journal of Clinical Investigation
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Effector/Memory but Not Naive Regulatory T Cells Are Responsible for the Loss of Concomitant Tumor Immunity
Yung-chang Lin
The Journal of Immunology, 2009
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Persistence of tumor-infiltrating CD8 T cells is tumor-dependent but antigen-independent
Jianzhu Chen
Cellular & Molecular Immunology, 2011
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The Tumoricidal Activity of Memory CD8+ T Cells Is Hampered by Persistent Systemic Antigen, but Full Functional Capacity Is Regained in an Antigen-Free Environment
Cornelis Melief
The Journal of Immunology, 2004
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Absence of CD4 T-cell help provides a robust CD8 T-cell response while inducing effective memory in a preclinical model of melanoma
Fabian Benencia
Immunotherapy, 2012
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Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8 T Cells in Patients with Melanoma
Lien Ngo
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Modeling the CD8+ T Effector to Memory Transition in Adoptive T-Cell Antitumor Immunotherapy
Cleo Rolle
Cancer Research, 2008
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Generation of highly activated, antigen-specific tumor-infiltrating CD8+ T cells induced by a novel T cell-targeted immunotherapy
Marianne Stanford
OncoImmunology
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Direct tumor recognition by a human CD4+ T-cell subset potently mediates tumor growth inhibition and orchestrates anti-tumor immune responses
Sacha Gnjatic
Scientific Reports, 2015
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Divergent Roles for CD4+ T Cells in the Priming and Effector/Memory Phases of Adoptive Immunotherapy
Hong-Ming Hu
The Journal of Immunology, 2000
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Therapeutic limitations in tumor-specific CD8+ memory T cell engraftment
Biao He
BMC cancer, 2003
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Combination of 4-1BB Agonist and PD-1 Antagonist Promotes Antitumor Effector/Memory CD8 T Cells in a Poorly Immunogenic Tumor Model
Winston Evering
Cancer Immunology Research, 2014
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