original ) (raw )The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations
Michelle Maritz
Scientific Reports, 2019
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The Progestin Medroxyprogesterone Acetate Affects HIV-1 Production in Human Lymphoid Tissue Explants in a Dose-Dependent and Glucocorticoid-like Fashion
Christophe Vanpouille
Viruses, 2021
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Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels
Michele Tomasicchio
PloS one, 2018
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Hormonal Contraception and HIV-1 Infection: Medroxyprogesterone Acetate Suppresses Innate and Adaptive Immune Mechanisms
richard huijbregts
Endocrinology, 2013
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Long-term effect of depot medroxyprogesterone acetate on vaginal microbiota, epithelial thickness and HIV target cells
Dorothy Patton
Journal of Infectious Diseases, 2014
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Regular use of depot medroxyprogesterone acetate causes thinning of the superficial lining and apical distribution of HIV target cells in the human ectocervix
Julius Oyugi
The Journal of Infectious Diseases
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Exploring the immunomodulatory role of depot medroxyprogesterones acetate and endogenous progesterone levels in HIV infected and uninfected women
Dhayendre Moodley
BMC Research Notes
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Hormone regulation of the mucosal environment in the reproductive tract and the prevention of HIV infection
Fulvia Veronese
American journal of reproductive immunology (New York, N.Y. : 1989), 2014
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Ex Vivo Effect of Estrogen and Progesterone Compared With Dexamethasone on Cell-Mediated Immunity of HIV-Infected and Uninfected Subjects
Doug Mack
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2007
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The Progestin-Only Contraceptive Medroxyprogesterone Acetate, but Not Norethisterone Acetate, Enhances HIV-1 Vpr-Mediated Apoptosis in Human CD4+ T Cells through the Glucocorticoid Receptor
Michele Tomasicchio
PLoS ONE, 2013
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Sex Hormones Selectively Impact the Endocervical Mucosal Microenvironment: Implications for HIV Transmission
Natalia Guerra-Pérez
PLoS ONE, 2014
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Pregnancy hormones, estrogen and progesterone, prevent HIV-1 synthesis in monocytes but not in lymphocytes
Aldar Bourinbaiar
FEBS Letters, 1992
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Pregnancy hormones, estrogen and progesterone, prevent HIV-1 synthesis in monocytes bu not in lymphocytes
Aldar Bourinbaiar
Febs Letters, 1992
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Association between use of the progestin Depot Medroxyprogesterone Acetate and Female Genital Proinflammatory Cytokines among HIV-1 and HSV-2 co-infected African women: a case control study
Edwin Owino Oloo Walong
2016
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Increased Cervical CD4+ CCR5+ T Cells Among Kenyan Sex Working Women Using Depot Medroxyprogesterone Acetate
Geneviève Boily-Larouche
AIDS Research and Human Retroviruses, 2019
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Increased Cervical CD4+CCR5+ T Cells Among Kenyan Sex Working Women Using Depot Medroxyprogesterone Acetate
Julius Oyugi
AIDS Research and Human Retroviruses, 2018
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Progesterone inhibits HIV-1 replication in human trophoblast cells through inhibition of autocrine tumor necrosis factor secretion
Laura Díaz
Journal of Infectious …, 2007
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Association of endogenous progesterone levels in young women using hormonal contraception with recent HIV-1 infection
Dhayendre Moodley
BMC Women's Health
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Endometrial Epithelial Cell Responses to Coinfecting Viral and Bacterial Pathogens in the Genital Tract Can Activate the HIV-1 LTR in an NF B-and AP-1-Dependent Manner
Aisha Nazli
Journal of Infectious Diseases, 2011
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Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in a Kenyan sex worker cohort and is also associated with increased susceptibility to HIV-1 in humanized mice
Julius Oyugi
Disease Models & Mechanisms
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Interaction of Pregnancy Steroid Hormones and Zidovudine in Inhibition of HIV Type 1 Replication in Monocytoid and Placental Hofbauer Cells: Implications for the Prevention of Maternal-Fetal Transmission of HIV
Andrew Lee
AIDS Research and Human Retroviruses, 1997
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Association between use of the progestin Depot Medroxyprogesterone Acetate and Cervicovaginal Lavage Proinflammatory Cytokines among HIV-1 and HSV-2 co-infected African women: a case control study
CHRISTOPHER GONTIER
bioRxiv, 2016
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Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate
Julius Oyugi
PLOS Pathogens
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Genital Tract Viral Load in HIV Type 1-Positive Women Correlates with Specific Cytokine Levels in Cervical-Vaginal Secretions But Is Not a Determinant of Infectious Virus or Anti-HIV Activity
Mimi Ghosh
AIDS Research and Human Retroviruses, 2012
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The Contribution of Cervicovaginal Infections to the Immunomodulatory Effects of Hormonal Contraception
Christine Mauck
mBio, 2015
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Loss of genital epithelial barrier function is greater with depot-medroxyprogesterone acetate than intravaginal rings that release etonogestrel and ethinyl estradiol
Kristen Aceves
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HIV-1 Genital Shedding is Suppressed in the Setting of High Genital Antiretroviral Drug Concentrations Throughout the Menstrual Cycle
A. Adesoye , D. Danavall , C. Gatcliffe
Journal of Infectious Diseases, 2014
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Productive HIV-1 infection of human cervical tissue ex vivo is associated with the secretory phase of the menstrual cycle
Massimo Origoni
Mucosal Immunology, 2013
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Pharmacokinetic and pharmacodynamic impacts of depot medroxyprogesterone acetate use on HIV pre-exposure prophylaxis in women
Sharon Achilles
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2020
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Vaginal Epithelium Transiently Harbours HIV-1 Facilitating Transmission
sukeshani salwe
Frontiers in Cellular and Infection Microbiology
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