Rapid green synthesis of silver nanoparticles from silver nitrate by a homeopathic mother tincture Phytolacca Decandra (original) (raw)

In the current study, the Ethiopian cactus pear fruit peel infusions were used as a phytoreducing agent to fabricate silver nanoparticles (CPFP-AgNPS). The formation of AgNPS in 7 min was confirmed by Ultra UV-Vis spectral portrait. The average size range (20-60 nm), the composition of silver element and crystal structure of the CPFP-AgNPS was established by transmission electron microscopy, energy dispersive X-ray spectra and X-ray diffraction analysis respectively. The CPFP-AgNPS exhibited greater inhibition (81.92%) on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical assay. The antibacterial activity of CPFP-AgNPS was high in the order against E.coli > Salmonella spp. > Bacillus spp. > Pseudomonas spp. > Staphylococcus spp. respectively. The CPFP-AgNPS also showed effective anticancer activity against human cervix epithelioid carcinoma cell lines with an IC 50 value of 74.26 ± 0.25 µg mL −1 /24 h. In short, the findings highlighted the effectiveness of CPFP-AgNPS on potential therapeutic applications.