P016 Selected trans-Himalayan medicinal plants and their nano-particles express potent antifungal and antibiofilm activity against Candida auris and Candida glabarata (original) (raw)

Poster session 1, September 21, 2022, 12:30 PM - 1:30 PM Normal microbiota turned opportunistic pathogen Candida glabrata and pathogenic Candida auris are becoming major health concerns globally. Antimicrobial resistance is growing gradually now, even the newer antibiotics alone are not able to completely irradicate the resistant microorganisms. This dire situation reflects the need to have an alternative regime, especially with a diverse range of applicability. Nanoparticles synthesized from medicinal plants are emerging as potent antifungal agents to battle against fungal pathogens with unique antimicrobial properties. Secondary metabolites obtained from the herbs like alkaloids, carbohydrates, esters, flavonoids, glycosides, lignin, phenol, steroids, tannin, etc are robust therapeutic and immune-modulator compounds. The selected herbs (Aconitum heterophyllum, Allium ursinum, Paris polyphylla, Podophyllum hexandrum, Rheum austral, and Selenium vaginatum) in this study have a diver...