Pyogenic granuloma arising within capillary malformations in children: A case report and literature review (original) (raw)

Congenital Disseminated Pyogenic Granuloma

Pediatric Dermatology, 2009

In the past pyogenic granuloma (PG) in infancy has been easily confused clinically and histopathologically with infantile hemangioma (IH). In 2000 North and colleagues discovered that IH is immunopositive for GLUT-1, a glucose transporter which is also expressed in placental capillaries (1). GLUT-1 staining is negative in pyogenic granuloma. We report two newborns with congenital disseminated PG who were otherwise healthy. In both of these cases, negative GLUT-1 staining supported the proper diagnosis.

Uncommon location of pyogenic granuloma in a child – case report and mini-review

Archives of the Balkan Medical Union, 2020

Localisation peu fréquente du granulome pyogène dans l'enfance-cas clinique et mini-revue Introduction. Le granulome pyogène (GP) est une hyperplasie inflammatoire vasculaire qui affecte la peau et la muqueuse buccale, souvent associée à une irritation ou un traumatisme local, ou à une grossesse. La localisation intra-orale affecte généralement la gencive, mais l'aspect tumoral peut être trompeur, en particulier dans les localisations extra-gingivales. Une évaluation et un diagnostic approfondis sont donc importants pour garantir un traitement approprié. Présentation du cas. Nous présentons le cas d'un garçon de 12 ans qui est venu pour une consultation concernant la tumeur croissante et saignante de sa muqueuse de la lèvre inférieure. La tumeur a été étiquetée comme « hémangiome ». Elle se développait depuis plusieurs semaines et avait été associée à un traumatisme muqueux mineur mais répété. Bien que la localisation anatomique ne soit pas courante, les antécédents du patient suggéraient un diagnostic de GP. Après une consultation dermatologique qui proposait un diagnostic différentiel avec le papillome buccal, une échographie des tissus mous avait soutenu le diagnostic clinique. La tumeur a été excisée chirurgicalement et ABSTRACT Introduction. Pyogenic granuloma (PG) is a vascular inflammatory hyperplasia involving the skin and oral mucosa, often associated with local irritation or trauma, or with pregnancy. Intraoral location usually affects the gingiva, but tumoral aspect can be misleading, especially in extra-gingival locations. A thorough assessment and diagnosis are therefore important for ensuring the proper treatment. Case presentation. We report the case of a 12-year-old boy who presented for a growing and bleeding tumour of his lower lip mucosa. The tumour was labeled as "hemangioma". It was growing for several weeks and associated with minor, but repeated mucosal trauma. Although the anatomic location was not common, the patient history suggested a diagnosis of PG. After a dermatologic assessment, which proposed a differential diagnosis with oral papilloma, a soft tissue ultrasound sustained the clinical diagnosis. The tumour was surgically excised and the defect was closed directly with absorbable sutures. Three weeks later the mucosa had a healthy appearance, without signs of impaired healing or tumour recurrence. The histopathological exam confirmed the clinical diagnosis. Conclusions. There are several types of soft tissue solid or vascular tumours that can be mislabeled and

Multifocal congenital pyogenic granuloma successfully treated with oral propranolol

Pediatric Dermatology, 2018

Disseminated congenital pyogenic granuloma (DCPG) is an uncommon condition. Individual lesions of DCPG share clinical and histologic similarities with infantile hemangioma (IH); endothelial glucose transporter 1 (GLUT-1), which is highly expressed in IH but generally not in pyogenic granulomas (PG), is an important diagnostic tool. Treatment for DCPG remains difficult. We describe a case of DCPG effectively treated with propranolol.

Capillary Hemangioma Mimicking Pyogenic Granuloma: A Case Report

2018

Capillary haemangioma and pyogenic granuloma are well known and commonly occurring benign vascular malformations of the oral cavity exhibiting varied age from infants to late adulthood. Pyogenic granuloma occurs generally on the gingiva, whereas capillary haemangioma preferred sites are lips and tongue. Both lesions are very rarely seen on the palatal region1. Pyogenic granuloma is a relatively common, soft tissue tumour of the oral cavity that is believed to be reactive and non neoplastic in nature. The name pyogenic granuloma is a misnomer since the condition is not associated with pus and does not represent a granuloma histologically. 2 Haemangioma are the benign tumours composed of blood vessels and are classified on the basis of their histological appearance as capillary, mixed cavernous or a sclerosing variety that tends to undergo fibrosis 3. Haemangioma show characteristic feature of rapid endothelial cell proliferation, followed by involution over time. The proliferating ma...

Pyogenic Granuloma ( PG )-Common Lesion at Uncommon Site Case Report

2019

Pyogenic tumor or pregnancy tumor or lobular capillary hemangioma is an inflammatory hyper plasia occurs in oral cavity, due to hormonal effects on blood vessels. It is not a true granuloma or infection, and caused by localised irritation, hormones, trauma seen in between 2nd to 5th decade, more common in pregnant females occurs in gingiva most commonly, then lip, buccal mucosa, tongue, floor of mouth and rarely in hard palate. In this we are going to present a rare case of pyogenic granuloma of hard palate and detailed review in correlation with pregnant females.

Recurrent Pyogenic Granuloma caused by Intraosseous Vessel: A Case Report

Pyogenic granuloma is a benign localized lesion of the skin and mucosa closely related to trauma, chronic irritation and hormonal changes. The method of treatment is surgical excision. However relapses can occur. For this reason, treatment with alternative methods such as cryotherapy, electrocautery and laser has been investigated in recent years. In this case, the cause of PG was a feeder vessel. The lesion was excised before and recurred within two weeks. An intraosseous feeder vessel was identified by a magnetic resonance imaging. This vessel was exposed and cauterized with electrocautery.

Self-progressing Granulomatous Growth in Pediatric Patients: Pyogenic Granuloma?

International Journal of Preventive and Clinical Dental Research, 2016

Fibrous overgrowths of soft tissues in oral cavity are relatively common and may be quite challenging to diagnose. Pyogenic granuloma is one such entity which occurs commonly in response to chronic local irritation, e.g., calculus, fractured tooth or restoration, foreign materials, etc. It occurs predominantly in females, probably due to the action of female hormones. These lesions are generally asymptomatic and are reported only due to difficulty in mastication. Treatment includes complete excision of the lesion along with the removal of causative factor. This paper describes a case of pyogenic granuloma in a ten-anda-half-year-old girl, presenting with a single, irregular, reddish maxillary gingival swelling in relation to mobile 63.

Pyogenic granuloma. A case report

Journal of the American Podiatric Medical Association, 1973

Pyogenic granuloma is a fast growing reactive proliferation of endothelial cells commonly on the gingiva and usually in response to chronic irritation. It is a polypoid form of capillary hemangioma on the skin & mucosal surfaces. This paper present of case of pyogenic granuloma found on the cheek adjacent to retromolar region.