Integrated requirement of non-specific and sequence-specific DNA binding in MYC-driven transcription (original) (raw)

The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site

Linda Sealy

Genes & Development, 1994

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Different promoter affinities account for specificity in MYC-dependent gene regulation

Caroline Kisker

eLife, 2016

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Generic binding sites, generic DNA-binding domains: where does specific promoter recognition come from?

Adrien Georges

The FASEB Journal, 2010

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Sequence specificity incompletely defines the genome-wide occupancy of Myc

Raluca Gordân

Genome Biology, 2014

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c-Myc Target Gene Specificity is Determined by a Post-DNA-Binding Mechanism

Kathryn Boyd

Proceedings of The National Academy of Sciences, 1998

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Selective transcriptional regulation by Myc: Experimental design and computational analysis of high-throughput sequencing data

Stefano de Pretis

Data in Brief, 2015

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Dissecting transcriptional amplification by MYC

Stoney Simons

eLife

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I-Motif Structures Formed in the Human c-MYC Promoter Are Highly Dynamic–Insights into Sequence Redundancy and I-Motif Stability

Emmanuel Hatzakis

PLOS One, 2010

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Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex

Sidra Khan

Molecular Systems Biology, 2011

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The Chromatin Structure of the Dual c-myc Promoter P1/P2 Is Regulated by Separate Elements

Gertraud Stelzer

Journal of Biological Chemistry, 2001

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A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif

Gregory Michelotti

Genes & Development, 1994

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Positive control mutations in the MyoD basic region fail to show cooperative DNA binding and transcriptional activation in vitro

Eyal Bengal

Proceedings of the National Academy of Sciences, 1994

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Myc represses transcription through recruitment of DNA methyltransferase corepressor

Arantxa Gutierrez

The EMBO Journal, 2004

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In silico identification of transcriptional regulators associated with c-Myc

Ron Shamir

Nucleic Acids Research, 2004

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E-box-independent regulation of transcription and differentiation by MYC

S. Benitah, Arantxa Gutierrez

Nature Cell Biology, 2011

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A nuclease hypersensitive element in the human c-myc promoter adopts several distinct i-tetraplex structures

M. Vorlickova

Biochemical and Biophysical …, 2000

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Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding

Sam John

BMC Genomics, 2013

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Integration of genome and chromatin structure with gene expression profiles to predict c-MYC recognition site binding and function

Yili Chen, David States

PLoS computational biology, 2007

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Transcription factor binding at enhancers: shaping a genomic regulatory landscape in flux

Robert-Jan Palstra

Frontiers in Genetics, 2012

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Highly conserved features of DNA binding between two divergent members of the Myb family of transcription factors

Benoit Pinson

Nucleic Acids Research, 2001

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Acting locally and globally: Myc's ever-expanding roles on chromatin

Natalia Varlakhanova

Cancer research, 2009

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Stimulation of Myc transactivation by the TATA binding protein in promoter-reporter assays

John Barrett

2005

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Absence of a simple code: how transcription factors read the genome

Matthew Slattery, Remo Rohs, Raluca Gordân

Trends in Biochemical Sciences, 2014

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Chromatin regulates genome-wide transcription factor binding affinities

Colin Logie

bioRxiv, 2022

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A Triplex-forming Sequence from the Human c-MYC Promoter Interferes with DNA Transcription

Philip Hanawalt

Journal of Biological Chemistry, 2007

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DNA oxidation drives Myc mediated transcription

Enrico V. Avvedimento

Cell Cycle, 2010

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Promoter type influences transcriptional topography by targeting genes to distinct nucleoplasmic sites

PETER COOK

Journal of Cell Science, 2013

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The transcriptional control proteins c-Myb and v-Myb contain a basic region DNA binding motif

Richard Mott

FEBS Letters, 1991

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A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding

Ray Ko

Molecular Cancer, 2008

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Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

Amber Afroz

2010

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Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation

Alessandro Verrecchia

Genome Research, 2017

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Decoupling of divergent gene regulation by sequence-specific DNA binding factors

Michael Mwangi

Nucleic Acids Research, 2015

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Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoter

Marilda Lipp

Genes & Development, 1989

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