A Study on Role of Magnetic Resonance Imaging (MRI) in Intracranial Space Occupying Lesions (original) (raw)
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Imaging of Intracranial Space Occupying Lesions
International Journal of Medical and Biomedical Studies, 2021
Introduction: With advanced MRI techniques such as perfusion, diffusion, and spectroscopy, it is now possible to differentiate between various intracranial lesions. Materials and Methods: This prospective cohort study was conducted on 50 patients referred by various clinical departments with clinical suspicion of intracranial space occupying lesions, evaluated by computed tomography & magnetic resonance imaging. Result: Solitary lesions were present in 35 patients (70%) & multiple lesions in 15 patients (30%). 68.00% lesions were Supratentorial & 32.00% infratentorial in location. Most common supratentorial location in adults was frontal lobe 40% followed by parietal lobe 30%. Most common supratentorial locations in children were frontal lobe. Infratentorially, cerebellum & posterior fossa were found to be most common location in adults & children respectively. Supratentorial lesions were most common both in adults & children. 60% lesions were intraaxial & 40 % extra axial in locati...
https://www.ijhsr.org/IJHSR\_Vol.8\_Issue.4\_April2018/IJHSR\_Abstract.031.html, 2018
Intracranial space occupying lesions (ICSOL) represent one of the most commonly encountered abnormalities in brain. The availability of computed tomography (CT) and conventional magnetic resonance imaging (MRI) have revolutionised the approach towards diagnosis and management of intracranial lesions. Majority of intracranial lesions can be reliably diagnosed on conventional MRI. However many times it is difficult to differentiate brain pathologies on the basis of CT scan or conventional MRI. In such cases, advanced MRI sequences such as diffusion weighted imaging (DWI), perfusion weighted imaging (PWI) and proton magnetic resonance spectroscopy (MRS) can be helpful in making a reliable and accurate diagnosis. Herein, we describe importance of advanced MRI sequences in diagnosing various ICSOLs which were extremely hard and confusing to differentiate on conventional MRI.
IP innovative publication pvt ltd, 2020
Introduction: Intracranial space occupying lesion (ICSOL) are infective and non-infective conditions, which can infect and occupy space in brain parenchyma. These ICSOL produce characteristic symptom and signs. If these symptom and signs are identified at an early stage of disease, more than half of these ICSOL are amenable to treatment Objective: Our study was done to identify the incidence of ICSOL in our city, along with the various co factors such as the gender, age socioeconomic condition and other risk factors. We also determined the prognosis of various ICSOL and Materials and Methods: Patients admitted in RKDF Medical College and Hospital, Bhopal in the department of Medicine, Neurology and Neurosurgery department with history and clinical features suggestive of intracranial space occupying lesion. Results: The study sample size included 30 patients, Of the 30 patients studied, 17 were male and 13 were female patients. Infective ICSOL was found to be more common in young age, while non infective was more common in old age. Common infective(16) causes, were Neurocysticercosis, Tuberculoma, Toxoplasmosis and Brain abscess. Non infective ICSOL accounted for 14 cases. Common non infective ICSOl were Glioma meningioma had the second highest incidence. Conclusion: The prevalence of ICSOL was found to be around 0.01%. Infective SOL was found to be more common in males during second and third decade. While Non infective SOL was found to be more common in females during sixth and seventh decade. ICSOL were associated with features of raised ICT, seizure or focal neurological deficit.. Radiologically, they were characterized by multiple or single well circumscribed ring-enhancing lesion. Aims and Objectives: 1: To find out the prevalence of intracranial space occupying lesion (ICSOL) and different causes of intracranial space occupying lesion in RKDF Medical college hospital and research center Bhopal during one year period between 01/03/2018 - 28/02/2019. 2: To find out the clinical features and CT Scan features of various intracranial space occupying lesion and their correlation (CT/Clinical).
International Journal of Current Advanced Research, 2017
Distributions of tumor types vary substantially by age group and among the developing/developed countries. Data from several national cancer registries support differences in the epidemiology of brain tumors in children versus adults. High-grade glioma (30.5%) and meningioma (29.4%) are the most common types of adult primary brain tumors (data taken from the Swedish cancer registry). Males also generally have higher rates of primary malignant brain tumors while females have higher rates of non-malignant tumors, primary meningiomas. 1 During the last few years, the role of magnetic resonance imaging (MRI) as a diagnostic tool in neuroradiology is well-established. With advanced MRI techniques such as perfusion, diffusion, and spectroscopy, it now possible to differentiate between various intracranial lesions. The differential diagnosis of intra cerebral necrotic tumors and the cerebral abscess is frequently difficult on
2016
Introduction: The high morbidity & mortality associated with ICSOLs necessitates their early diagnosis so as to plan the required intervention. Intracranial Space occupying lesions (ICSOL) can be neoplastic, inflammatory or infective in aetiology. Widely available imaging techniques, computed tomography (CT) & magnetic resonance imaging (MRI) are used to detect these lesions. This study was done to evaluate the ICSOL on neuroimaging & correlate the clinical findings with the radiological assessment. Methods: In this prospective cohort study, 80 patients with ICSOL were studied by CT & MRI. Imaging findings were evaluated & tabulated & correlated with the clinical findings & histopathological findings (wherever available). The findings were statistically analyzed. Results: Most patients were in age range of 31 – 50 years (mean 42.2 y). Male : females ratio was 3:2. Most common presenting symptom was headache. Solitary lesions were present in 58 patients (72.5%) and multiple lesions i...
Computed Tomography Evaluation of Intracranial Space Occupying Lesions in Adults
2014
Introduction: Neoplasms of the brain present a remarkably diverse spectrum of growths. Computed tomography (CT) has now become the primary imaging modality for intracranial space occupying lesions (SOL) with effi cacy of 90-98%. Aim: The aims and objectives of this study are to know the frequency of occurrence of various intracranial SOL in adults and to analyze the CT brain scan data to determine the diagnostic sensitivity and specifi city of CT. Materials and Methods: A total of 100 cases of intracranial SOL were studied in patients above the age group of 18 years. Patients were followed up over a period of 2 years for histological co-relation. Data collected was analyzed with review of the literature. Results: This review has indicated that intracranial SOL often show characteristic features on CT that help in making a confi dent diagnosis. It is possible to attempt grading of the tumor with a fair degree of reliability. Conclusion: CT assessment supported by a sound understandin...
Cureus, 2019
Purpose: Our aim was to determine the diagnostic performance of the combined usage of diffusion-weighted imaging (DWI), magnetic resonance spectroscopy (MRS) and perfusion MR (MRP) imaging for the differential diagnosis of benign and malignant intracranial lesions. Materials and methods: A total of 30 patients with intracranial lesions who were prospectively evaluated with contrast-enhanced magnetic resonance imaging (MRI), DWI, MRS, and MRP were included in this study. The lesions were classified as benign and malignant according to the radiologic findings. All imaging data were compared with the histopathologic results and follow-up of the patients. We used the Pearson chi-square test and Fischer's exact t-test for statistical analysis. Results: For the differentiation of benign and malignant brain lesions, CBV and choline/creatine (Cho/Cr) ratio at short echo time (TE) had the highest sensitivity (87%-88%), Cho/N-acetyl aspartate (NAA) at short TE had the highest specificity (86%). DWI predicted 77% sensitivity, 75% specificity; MRP presented 91% sensitivity, 88% specificity; MRS yielded 77% sensitivity, 63% specificity. The combination of either DWI and MRS, MRP and MRS or DWI+MRS+MRP revealed 100% sensitivity, 100% specificity. Conclusion: For the differentiation of benign and malignant brain lesions, the combination of DWI, MRS, and MRP predicted 100% sensitivity. Invasive procedures like transcranial biopsy were not required via the usage of these advanced MRI techniques.
Multislice Computed Tomographic Evaluation of Intracranial Space Occupying Lesions
Introduction: The term intracranial space occupying lesions includes lesions which expand in volume to displace normal neural structures. They give rise to the various symptoms like focal seizures, paralysis, features of raised intracranial tension and false localizing signs. AIMS & OBJECTIVES: To determine the role of computed tomography in evaluation of space occupying lesions of brain, assessment of the site, nature and extent, age and sex prevalence of space occupying lesions. MATERIAL & METHODS: The present study was conducted on one hundred patients with space occupying lesions of the brain presenting with various neurologic symptoms or incidental findings. Patients of all age groups suspected to have intracranial space occupying lesions were included in the study. Results were expressed as mean ± SD and proportions as percentages. Results: Most of the cases of hyperdense lesions were intracerebral hemorrhages, meningioma, lymphoma and medulloblastoma. High grade astrocytomas were heterogenous hypodense lesions with irregular ring enhancement associated perilesional edema and mass effect. Low grade astrocytomas had minimal rim/ mural nodule enhancement. Intracranial tuberculoma and neurocysticercosis showed ring with nodular enhancing. Calcification was seen in tuberous sclerosis, neurocysticercosis, meningiomas, oligodendrogliomas, arteriovenous malformations and dermoid cyst. Congenital lesions had variable presentation ranging from cystic to mixed pattern lesions. CONCLUSIONS: In developing countries, CT imaging remains as a major diagnostic modality, with easy accessibility and technical ease as compared to MRI.
Journal of Datta Meghe Institute of Medical Sciences University
Background: Tumors of Central Nervous System constitute approximately 2% of all malignancies. Cancers of the central nervous system (CNS) are considered to be among the most notorious of all cancers. Low-grade cns tumors have been found over time to progress to high grade tumors. CNS is a common site for metastasis from other organs. Due to newer techniques used in radio diagnosis and stereotactic biopsies, more & more CNS tumors are being diagnosed & are being operated upon. Aims and objectives: The objective of this article is to provide an overview of intracranial and intraspinal space occupying lesions at a single tertiary care referral center. The aim was to study incidence of various lesions in light of the WHO classification of tumours of the central nervous system, 2016 and to study relevant statistics.
Zenodo (CERN European Organization for Nuclear Research), 2018
Background: Tumors of Central Nervous System constitute approximately 2% of all malignancies. Cancers of the central nervous system (CNS) are considered to be among the most notorious of all cancers. Low-grade cns tumors have been found over time to progress to high grade tumors. CNS is a common site for metastasis from other organs. Due to newer techniques used in radio diagnosis and stereotactic biopsies, more & more CNS tumors are being diagnosed & are being operated upon. Aims and objectives: The objective of this article is to provide an overview of intracranial and intraspinal space occupying lesions at a single tertiary care referral center. The aim was to study incidence of various lesions in light of the WHO classification of tumours of the central nervous system, 2016 and to study relevant statistics.