Immunogenomics of Hypermutated Glioblastoma: a Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy (original) (raw)

Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape

cecile Maire

Acta Neuropathologica Communications

View PDFchevron_right

Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency

Roula Farah

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016

View PDFchevron_right

TMIC-26. Immunomodulation with Temozolomide to Improve Efficacy of Immune Checkpoint Inhibition for the Treatment of Glioblastoma

Farhad Dastmalchi

Neuro-Oncology, 2017

View PDFchevron_right

Investigation of the relationship between immune checkpoints and mismatch repair deficiency in recurrent and nonrecurrent glioblastoma

ismail Saygın

Turkish Journal of Medical Sciences, 2021

View PDFchevron_right

Detection of temozolomide-induced hypermutation and response to PD-1 checkpoint inhibitor in recurrent glioblastoma

Janusz Rak

Neuro-Oncology Advances

View PDFchevron_right

Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes

cecile Maire

Clinical Cancer Research

View PDFchevron_right

Tumor Mutation Burden, Expressed Neoantigens and the Immune Microenvironment in Diffuse Gliomas

Olga Kim

Cancers, 2021

View PDFchevron_right

Treatment of an aggressive orthotopic murine glioblastoma model with combination checkpoint blockade and a multivalent neoantigen vaccine

Connor Liu

Neuro-Oncology, 2020

View PDFchevron_right

Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma

Louis Boon

Oncoimmunology, 2017

View PDFchevron_right

Tumoral and immune heterogeneity in an anti-PD-1 responsive glioblastoma: a case study

Ilaria Laface

Molecular Case Studies

View PDFchevron_right

Predictive markers of immune response in glioblastoma: hopes and facts

Stefania Bartolini

Future Oncology, 2020

View PDFchevron_right

Biomarkers for immunotherapy for treatment of glioblastoma

Kwadwo Sarpong

Journal for ImmunoTherapy of Cancer

View PDFchevron_right

Recurrence- and Malignant Progression-Associated Biomarkers in Low-Grade Gliomas and Their Roles in Immunotherapy

Siyi Wanggou

Frontiers in Immunology, 2022

View PDFchevron_right

Analysis of Histomorphological/molecular Association and Immune Checkpoint Regulators in Epithelioid Glioblastoma and Pleomorphic Xanthoastrocytoma: Are These Tumors Potential Candidate for Immune Checkpoint Blockade

Arvind Ahuja

2021

View PDFchevron_right

Checkpoint inhibitor failure in hypermutated and mismatch repair-mutated recurrent high-grade gliomas

Haroon Ahmad

Neuro-Oncology Practice, 2019

View PDFchevron_right

Immune check-point in glioblastoma multiforme

Francesca De Felice

Critical Reviews in Oncology Hematology, 2019

View PDFchevron_right

Molecular portrait of a rare case of metastatic glioblastoma: somatic and germline mutations using whole-exome sequencing

Angelo Giovanni Bonadio

Neuro-Oncology, 2016

View PDFchevron_right

Genetic and Immune Changes Associated with Disease Progression under the Pressure of Oncolytic Therapy in A Neuroblastoma Outlier Patient

Gustavo Melen

Cancers

View PDFchevron_right

A Quantitative Digital Analysis of Tissue Immune Components Reveals an Immunosuppressive and Anergic Immune Response with Relevant Prognostic Significance in Glioblastoma

Miguel Idoate

Biomedicines

View PDFchevron_right

Analysis of immunobiologic markers in primary and recurrent glioblastoma

Jesse Kresak

Journal of neuro-oncology, 2018

View PDFchevron_right

Glioblastoma: Pitfalls and Opportunities of Immunotherapeutic Combinations

Gabriela kramer-MareK

OncoTargets and Therapy

View PDFchevron_right

Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma

Hadida Yasmin

Frontiers in Immunology, 2020

View PDFchevron_right

Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches

Francesca Piazzini

Journal of translational medicine, 2024

View PDFchevron_right

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma

Agnieszka Bronisz

Neuro-Oncology, 2017

View PDFchevron_right

CBM-06 * Immune Biomarker Results from a Trial of Nivolumab Ipilimumab in Patients with Recurrent Glioblastoma: CHECKMATE-143

jason simon

Neuro-Oncology, 2015

View PDFchevron_right

Immunotherapy for Glioblastoma: Current State, Challenges, and Future Perspectives

Arpan Mahanty

Cancers, 2020

View PDFchevron_right

Blocking immunosuppressive checkpoints for glioma therapy: the more the Merrier!

Pedro Lowenstein

Clinical cancer research : an official journal of the American Association for Cancer Research, 2014

View PDFchevron_right

Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma

Michael Fay

Oncotarget, 2021

View PDFchevron_right

Checkpoint Inhibitors as High-Grade Gliomas Treatment: State of the Art and Future Perspectives

Matteo Simonelli

Journal of Clinical Medicine, 2021

View PDFchevron_right

Current State of Immunotherapy for Treatment of Glioblastoma

Seema Nagpal

Current Treatment Options in Oncology

View PDFchevron_right

Immune genes are associated with human glioblastoma pathology and patient survival

A. Hamlat

2012

View PDFchevron_right

Immune Checkpoint Inhibitors in Gliomas

aaron tan

Current Oncology Reports, 2017

View PDFchevron_right

Deep immune profiling reveals targetable mechanisms of immune evasion in checkpoint blockade-refractory glioblastoma

Whitney Tamaki

2020

View PDFchevron_right

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial

Elisa Izquierdo

Cancer cell, 2018

View PDFchevron_right