Triplet pregnancy with complete mole (original) (raw)
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International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2017
Partial molar pregnancy is a rare entity in which there is usually a triploid abnormal foetus associated with a large placenta with cystic changes. The incidence of a normal diploid foetus and a partial molar placenta is extremely rare. Here we report a case of partial molar pregnancy in which a normal appearing foetus with diploid karyotype coexist. In this case a 24yr old primigravida at 20 week 3days gestation presented with 3-4 episodes of vaginal bleeding and generalised swelling of body since one month. On evaluation she was found to have moderate anaemia, proteinuria, raised serum β hcg and USG showed a single live foetus with thickened cystic placenta covering the internal os. After counselling patient was put up for hysterotomy. The product of conception and placenta were sent for histopathology and karyotyping which confirmed partial hydatidiform mole with trisomy 21 foetus. Patient had uneventful post op period and was followed up with serial β hcg measurement which fell ...
Atypical presentation of molar pregnancy
BMJ case reports, 2018
The classic features of molar pregnancy are irregular vaginal bleeding, hyperemesis, enlarged uterus for gestational age and early failed pregnancy. Less common presentations include hyperthyroidism, early onset pre-eclampsia or abdominal distension due to theca lutein cysts. Here, we present a case of molar pregnancy where a woman presented to the emergency department with symptoms of acute abdomen and was treated as ruptured ectopic pregnancy. The woman underwent laparoscopy and evacuation of retained products of conception. Histological examination of uterine curettage confirmed the diagnosis of a complete hydatidiform mole. The woman was discharged home in good general condition with a plan for serial beta-human chorionic gonadotropin (beta-hCG) follow-up. Complete follow-up includes use of contraception and follow-up after beta-hCG is negative for a year.
Term Delivery of a Complete Molar Pregnancy with a Coexistent Normal Pregnancy
Case Reports in Obstetrics and Gynecology, 2019
Twin pregnancy with a complete mole and a coexistent normal fetus reaching term is a rare occurrence. We report a case of a 21-yrs G2P1L0 un-booked patient at 39 weeks who was referred for the same condition diagnosed incidentally on ultrasound scan which showed a singleton pregnancy in breech presentation with a normal placenta and a heterogeneous cystic lesion seen anteriorly, suggesting a coexistent molar pregnancy. Cesarean section was done, and a healthy male baby was delivered with a grossly normal placenta and a second placenta with grape like vesicles. Histopathology confirmed the diagnosis of complete mole and normal placenta. Postoperative period was uneventful, and the patient was kept on beta hcg follow-up to monitor progression to gestational trophoblastic neoplasia, but it normalized by 12 weeks.
2018
DOI: 10.21276/sjmcr.2018.6.8.26 Abstract: Pregnancies with a hydatidiform mole and a live fetus are rare form of trophoblastic gestational disease, this situation occurs in about 1 in 20 000 to 1 in 100 000 gestations. The symptomatology is poor and the diagnosis can be made by ultrasound assessment. Management is still problematic seen that fetal survival is constrained by complications of molar pregnancy. The risk of persistent trophoblastic disease in twin molar pregnancies is higher compared to single mole .We report here a case of a woman who consulted for vaginal spotting and vomiting in the first trimester twin pregnancy with partial hydatidiform mole detected by ultrasound. Following spontaneous miscarriage, histopathological examination findings were compatible with a partial mole pregnancy coexisting with normal diploid fetus.
Partial hydatidiform mole and coexistent live fetus with placenta previa: a case report
Annals of medicine and surgery, 2023
Twin pregnancy of a hydatidiform mole with a coexistent live fetus is very rare, and complete molar pregnancy is involved in m ost cases. A partial molar pregnancy almost always ends in miscarriage due to a triploid fetus. Here, we report a case of a 32-year-old Chinese woman with ultrasound diagnosis o f a partial molar pregnancy. Amniocentesis suggested mosaicism, but the fetus was morphologically normal. The woman chose to continue the pregnancy aft er fully understanding the risk. The infant was delivered prematurely, and the presence of a large single placenta with molar changes. The baby's peripheral blood chromosomes were diploid, and the pregnant woman had no serious complications. The di agnosis, management, and monitoring of this condition will remain challenging because of its rarity. Partial hydatidiform mole combined with pregnancy can result in delivering of a normal fetus and live birth under proper management.
Complete Hydatidiform Mole Coexisting with Three Viable Fetuses in a Quadruplet Pregnancy
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2016
We hereby report a case of quadruplet pregnancy with delivery of 3 viable infants and a complete mole. This was an induced conception with clomiphene citrate. At 22 weeks, cystic structures were noticed in one of the placentae and a suspicion of co-existant molar pregnancy was made. The case discussed with oncologist and pregnancy was continued with close monitoring of β-hCG and Ultrasound. Her β-hCG at 23 weeks was 748 mIU/ml, which continued to rise until the 29th week of gestation to a level of 305881.68 mIU/ml and declined gradually thereafter. Similarly, hydropic change in placenta also continued to increase progressively. She was given steroid cover at 32 weeks and delivery was aimed at 34 weeks of gestation. The patient went into preterm labour at 33 weeks and 3 female infants delivered by lower segment cesarean section (LSCS) followed by removal of 3 placentae along with copious molar tissue at the end. The newborns were kept in the nursery, non-requiring assisted ventilatio...
European Journal of Human Health, 2021
Objective: A twin pregnancy with associated complete hydatidiform mole is a rare clinical entity which may present in different severe antenatal complications. The aim of this study is to present a case of twinning of a 37 weeks fetus and coexistent complete mole complicated with severe preeclampsia and emergency C-section with a healthy live born fetus. Case Report: A 32 year old G2 P1 pregnant woman who admitted at the perinatal center of maternity hospital was diagnosed a molar pregnancy coexisting with a healthy growing fetus at 10th weeks of gestation. At 32 weeks of gestation, preeclampsia was developed, the patient was followed until 37 weeks gestation when the clinical status of her turned into severe preeclampsia and cesarean section was carried out with the birth of a healthy fetus. Conclusions: Twinning with a coexistent complete hydatidiform mole may cause life-threatening complications for both fetus and the mother. Severe preeclampsia may be triggered in patients with coexisting molar pregnancy and such patients are recommended to be evaluated for molar pregnancy associating normal fetus that had a normal antenatal course in their previous pregnancies.
Molar pregnancy coexisting with a normal fetus: A case report
Gynecologic Oncology, 1989
Molar pregnancy with a coexisting live fetus is a rare occurrence. We present morphologic and cytogenetic analysis of a recent case. Cytogenetic studies revealed a 46, XX karyotype for the fetus, the normal placenta, and the abnormal placenta. Chromosome banding studies confirmed the presence of maternal and paternal chromosomes in all three tissues. These studies favored the possibility that both tumor and fetus arose from a single gestation. Subsequently, the patient required chemotherapy for low-risk, metastatic trophoblastic disease.
Journal of SAFOG, 2014
Gestational trophoblastic disease encompasses a diverse group of lesions. If molar changes in the placenta are known along with an alive fetus, then situation is difficult for both obstetrician and parents. On one hand, there may be a normal pregnancy whereas on the other hand the mother may be threatened by numerous complications caused by the hydatid mole, if the pregnancy is continued. We present successfully managed case of partial molar pregnancy with an alive fetus at 1st stage of preterm labor with premature rupture of membranes with anemia with a live diploid female fetus with good neonatal out come. Follow-up till 1 year showed no progression to malignant gestational trophoblastic diseases.