Squamous Cell Carcinoma of the Renal Pelvis: Rare Case Report (original) (raw)

Squamous cell carcinoma of the renal pelvis associated with kidney stones: radiologic imaging features with gross and histopathological correlation.

Squamous cell carcinoma (SCC) of the renal pelvis is a rare neoplasm and is usually associated with long standing renal stone disease. This tumor is aggressive in nature and usually has a poor prognosis. We report a case who presented with sudden significant weight loss. During the radiologic investigation, a renal mass and staghorn calculi were detected in the right kidney. The patient subsequently underwent right radical nephrectomy. Pathological diagnosis was SCC of renal pelvis with extensive infiltration in to the renal parenchyma. The radiologic imaging features and histopathologic findings of this rare tumor are discussed in this report.

Primary Squamous Cell Carcinoma of the Renal Pelvis: A Case Report Series

Curēus, 2024

Primary squamous cell carcinoma (SCC) of the renal pelvis is one of the extremely rare tumors encountered in the kidney. It poses a diagnostic challenge for both the clinician and pathologist alike due to the sheer rarity of its occurrence and the multitude nature of its clinical presentation. A review of the literature over the last few decades shows just a countable number of cases documented, each bearing the testimony of the aggressive nature of this subtype. We hereby report three cases of SCC of the renal pelvis origin received at a tertiary care hospital in North India.

Primary squamous cell carcinoma of kidney: a case report

International Surgery Journal, 2015

Neoplasms of the kidney are most commonly adenocarcinomas. Squamous cell carcinoma of renal pelvis and ureter are very rare and account for 6-15% of all renal tumours. Very few such cases have been reported. Most are associated with calculus disease or hydronephrosis. Our case was a 44year old female having pain & lump in right flank since six months. Contrast CT abdomen showed an 8.8x8.8x6.4 cm renal upper pole mass with well-defined rounded calcification invading directly into the liver. There was no calculus or hydronephrosis. Ultrasound guided tru-cut biopsy was inconclusive, showing only dysplastic cells. On exploration, the mass was found to be arising from postero-superior pole of right kidney, with direct invasion into the liver. A nephroureterectomy with wedge resection of liver was performed. Histopathology of the specimen showed well differentiated squamous cell carcinoma of renal pelvis extending into liver.

Squamous Cell Carcinoma of the Renal Pelvis, A Rare Site for a Commonly Known Malignancy

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016

Chronic nephrolithiasis predisposes to squamous metaplasia and subsequently SCC which is a rare malignancy of the upper urinary tract. A 60-year-old woman with a long standing history of renal calculi presented with flank pain and fever. Investigations revealed a mass in the superior pole of a non functioning left kidney while the right kidney was sub optimally functioning, hydronephrotic and there was presence of bilateral staghorn calculi. Patient underwent decompression of right kidney by double j stenting and left radical nephrectomy that revealed well differentiated squamous cell carcinoma of renal pelvis. Most SCC of the renal pelvis present with advanced disease and dismal prognosis while our patient presented with localized disease without lymphatic and distant metastasis. Thus radical nephrectomy can be curative if the disease can be diagnosed at an earlier stage. This emphasizes the need of early treatment of nephrolithiasis to prevent the development of SCC and screening of patients with long standing staghorn calculi.

Primary squamous cell carcinoma of kidney: A rare case report

Neoplasms of the kidney are most commonly adenocarcinomas. Carcinomas of the renal pelvis and ureter are rare, accounting for only 4% of all urothelial cancers. Squamous cell carcinoma (SCC) of renal pelvis and ureter are very rare and account for 6-15% of all renal tumors of which transitional carcinomas constitute the majority followed by adenocarcinoma and SCC. Renal SCC (RSCC) is a rare malignancy of the upper urinary tract characteristically presenting with advanced stage, the reported incidence being 1.4% of all renal malignancies. Very few cases have been reported in the literature. Most patients have a history of chronic urolithiasis, renal infection or abuse of analgesics. This tumor is aggressive in nature and usually has a poor prognosis. We report two cases of RSCC one with characteristic history of chronic pyelonephritis and one without characteristic etiologic factors. These cases have been reported due to their extreme rarity and also highlight the silent presentation of these tumors and the need to keep

Squamous Cell Carcinoma of Kidney and Its Prognosis: A Case Report and Review of the Literature

Case Reports in Urology, 2015

Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosis of squamous cell carcinoma of the renal pelvis is usually unsuspected due to the rarity and inconclusive clinical and radiological features. Most of the patients are diagnosed at an advanced stage and are with poor outcome. Radical nephrectomy is the mainstay of the treatment. We reported a case of squamous cell carcinoma of the kidney in a 50-year-old female who presented with the right sided abdomen pain. The patient was treated with radical nephrectomy.

Primary squamous cell carcinoma kidney: A rare case report

Our Dermatology Online, 2016

Primary squamous cell carcinoma (SCC) of the kidney is a very rare clinical entity. Only a few cases have been reported in world literature. Here we report a case with renal SCC. The patient presented with flank pain, fever and vomiting. In ultrasonography, renal mass was detected and after nephrectomy followed by histopathological examination, it was diagnosed as SCC. It was associated with renal calculi and hydronephrosis. The lack of characteristic presentation like hematuria, pain and palpable mass causes delay in diagnosis results in locally advanced or metastatic disease at presentation.

Primary renal squamous cell carcinoma – A rare entity

IP Archives of Cytology and Histopathology Research

Squamous cell carcinoma of kidney is the extremely rare entity of upper urinary tract neoplasm. The most common type of kidney cancer is clear cell renal cell carcinoma followed by papillary and chromophobe renal cell carcinoma. We report a case of renal cell carcinoma who presented with complaints of pain abdomen and hematuria. Radiologic investigation showed a renal mass and calculi in the left kidney. The patient subsequently underwent left radical nephrectomy. Pathological diagnosis of SCC of kidney was made. We report a rare case of primary renal squamous cell carcinoma involving whole of the kidney. With the best of our knowledge, only few cases of primary renal squamous cell carcinoma are reported.