A Comparison of Two Different Diets and Their Restricted Groups in Relation to Developmental Time and Viability in Drosophila melanogaster (original) (raw)

Effects of dietary restriction (DR) in ageing studies have been assessed for 70 years since the positive correlation between DR and median life span was first shown by McCay et al. in 1930’s [2]. There are strong evidences coming from several studies that show the prolongation of adult life span when they are fed on the diluted food medium [3-5]. Otherwise, it may be assessed to be a species-specific effect rather than a universal rule for all organisms [6]. However, there are lots of evidences coming from Drosophila studies, which already inspire scientists to focus on the effects of DR on ageing [7]. Dietary restriction is applied to Drosophila mostly at the adult stage and there are clear evidences that indicate lifespan extension with respect to restricted food medium when compared with standard medium [3,4,7]. However, different laboratories use different sources of yeast and different concentrations of sugar, yeast, and agar for DR [3,5,8-10]. From that point of view, Bass et ...