Hospital Based Study of Thyroid Disorders in Rural Population of Gurgaon, Haryana (original) (raw)
Related papers
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Introduction: Thyroid dysfunction is a common endocrine disorder, defined as the altered serum Thyroid Stimulating Hormone (TSH) levels with normal or altered FT3 and FT4 (triiodothyronine and thyroxine) levels. The spectrum of thyroid disorders includes hypothyroidism, hyperthyroidism, goiter/ iodine deficiency disorders, autoimmune thyroiditis, thyroid cancer, as well as subclinical hypothyroidism or hyperthyroidism. However, further research is required on the spectrum of thyroid disorders, apart from goiter/iodine deficiency disorders in the study population mentioned. Aim: To investigate the prevalence and patterns of thyroid disorders in the clinical biochemistry laboratory of a tertiary care hospital in the hilly region of Uttarakhand, India. Materials and Methods: Present cross-sectional study was conducted in the clinical biochemistry laboratory of Veer Chandra Singh Garhwali (VCSG) Govt. Institute of Medical Science and Research Centre, Srinagar Garhwal, Uttarakhand, India...
2020
Thyroid disorders are the most common endocrine diseases in India. Numerous studies in various countries differ in their prevalence rate for both hypothyroidism and hyperthyroidism. This present crosssectional observational study was conducted in Bankura Sammilani Medical College, Bankura, West Bengal to find out the prevalence of thyroid disorders among the people of this district. This present study was done over 700 patients, attending hospital suspected of having thyroid disorders, were screened for thyroid function. Serum samples were taken and serum Thyrotrophin (TSH) and free tetraiodothyronine (fT4) were estimated by ELISA method. Of this 700 study subjects, 17.14% were found to have thyroid dysfunction; among them, 7.43% had subclinical hypothyroidism, 5.57% had overt hyperthyroidism and 4.14% were suffering from hyperthyroidism. Females were affected more in both hypothyroidism and hyperthyroidism than males. The age group of 21-30 years was affected more than the others in all types of thyroid disorders.
Asian Journal of Medical Sciences, 2013
Background: Thyroid disorders constitute the most prevalent endocrine disorder in our country. Thyroid disorders are classified broadly as hyperthyroidism and hypothyroidism depending on the functional capacity of the thyroid gland. These two entities are further segregated as sub clinical and overt dysfunction. The present study attempts to evaluate the prevalence of thyroid disorders in north Indian population which is more prone to hypothyroidism due to iodine deficiency observed in the Himalayan belt.
Spectrum of thyroid dysfunction in patients visiting Kantipur Hospital, Kathmandu, Nepal
Mymensingh medical journal : MMJ, 2013
Thyroid disorder is most common endocrine abnormality in the general population and its prevalence increases with age. The screening of thyroid disorder is advised in high risk population. This hospital based cross-sectional study was conducted in Department of Biochemistry, Kantipur Hospital, Kathmandu, Nepal. Patients having complains of thyroid disease from February 2010 to January 2011 were enrolled in this study. Thyroid parameters such as FT3, FT4 and TSH were measured by ELISA technique. Among total 472 subjects 393(83.27%) were female whereas 79(16.73%) were male. The prevalence of thyroid dysfunction was 36.0% (n=170). The different patterns of thyroid dysfunction in Kathmandu valley were: hypothyroid (11.6%), subclinical hypothyroid (16.9%), hyperthyroid (4.0%), and subclinical hyperthyroid (3.6%) respectively. Subjects having all thyroid parameters normal i.e. euthyroid were 63.9%. In conclusion, this study reveals a higher prevalence of thyroid dysfunction in Kathmandu r...
Proportions of thyroid disorders in bhopal-a hospital based study
IP innovative publication pvt. ltd, 2019
Introduction: Thyroid disorder are multifactorial with contributions from genetic and environmental factors. The principal diseases of thyroid gland are goitre, hypothyroidism, hyperthyroidism, thyroiditis and neoplasms. Estimation of thyroid hormones and TSH are essential in arriving at a diagnosis of thyroid dysfunction. Objectives: To find out spectrum of thyroid dysfunction among study participants and to assess the association of thyroid disorders with socio-demographic variables Material and Methods: This was a facility based cross sectional study in Department of Biochemistry, for a period of one year from 1st April 2017 to 31st March 2018. All the individuals reporting for thyroid function tests in Biochemistry department for first time were included in the study using systematic random sampling. All participants included in the study were interviewed and information was recorded on a questionnaire. Observations: The mean age of study participants was 31.9±12.0 years. 414 (67.9%) participants were euthyroid, 158 (25.9%) were diagnosed as hypothyroid (21.8% subclinical and 4.1% overt), while only 38 (6.2%) were diagnosed as hyperthyroid (3.1 subclinical and 3.1 overt).
International Journal of Medical Science and Public Health, 2014
Background: Significant incidence of thyroid dysfunction, especially hypothyroidism, has been reported in Kashmir Valley of India. There is a paucity of studies that assessed the presence of thyroid dysfunction in various age groups of people in Srinagar. Objectives: This study aimed to investigate the prevalence of thyroid dysfunction in the local population who visit the outpatient department of Ramakrishna Mission Clinic at Srinagar. Materials and Methods: This work is a cross-sectional study carried out for 18 months. The study subjects were the patients who attended outpatient department of Ramakrishna Mission Clinic; patients referred by private practitioners of Srinagar and adjoining areas. The data were from those subjects who got thyroid function tests done for the first time. Thyroid function was assessed by clinical examination and thyroid function tests (T3, T4, and TSH). Results: The total number of subjects tested for thyroid function was 612 of which 120 were men and 492 were women. Total prevalence of thyroid disorders in the study population was 40.36% (247 of 612). Of the total 247 subjects with thyroid disorders, 17.8% were men (44) and 81.2% were women (203). Overall prevalence of subclinical hypothyroidism was 33% (206 of 612); prevalence of overt hypothyroidism was 5% (31 of 612); and prevalence of hyperthyroidism was 1.6% (10 of 612). Conclusion: There is a high prevalence of thyroid disorders in Kashmir population, and subclinical hypothyroidism is the most prevalent thyroid disorder. In females, maximum prevalence of subclinical hypothyroidism is seen in the reproductive age group.
Thyroid Function Status in Indian Adult Nonpregnant Females in Ranchi, India
Indian Journal of Medical Biochemistry
Aim Thyroid disorders are one of the most common endocrine diseases in India. Thyroid disorders are more common in women than in men and contribute to significant morbidity. In this postiodization era, there is paucity of pan-Indian data of thyroid disorder status among adult nonpregnant women. This study was done to analyze the thyroid hormone levels in women of Jharkhand region, which is traditionally known to be an iodine-deficient area. Materials and methods Three hundred and forty nonpregnant adult females in Ranchi area who were consuming iodized salt formed part of the study group. Clinical evaluation was done by a gynecologist pertaining to thyroid illness. Thyroid function tests encompassing triiodothyronine, thyroxine, and thyroid-stimulating hormone were carried out by quantitative enzyme immunoassay method. Thyroid status of the population was defined as per kit reference range. Results Subjects with age range 20 to 67 years were divided into three groups as per clinical...
Malnutrition, particularly iodine deficiency, is one of the major contributing factors to thyroid disorders in India. Poverty in India is contributing to the increase of thyroid disorders through malnutrition, poor sanitation, and lack of access to medical facilities. Another factor is the lack of awareness about the symptoms and risk factors of thyroid disorders. Intake recommendations for iodine are provided in the Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board (FNB) at the Institute of Medicine of the National Academies. WHO recommends universal iodinization of salt. High levels of iodine intake sometimes are associated with an increased risk of hyperthyroidism, hypothyroidism, or autoimmune thyroiditis. We conducted a retrospective study at our hospital from December 2017 to January 2023. A total number of 57 cases were studied. Out of 57 patients, 46 patients presented with hypothyroidism and 11 with hyperthyroidism. Various clinical presentations, pathologies and socioeconomic problems are discussed.
Spectrum of Thyroid Dysfunction in North Coastal Andhra Pradesh
Journal of Evidence Based Medicine and Healthcare, 2018
BACKGROUND The pathological spectrum of thyroid dysfunction varies from overactive to underactive thyroidism. It is a common Endocrine disorder worldwide and leads to major consequences in the absence of appropriate treatment. MATERIALS AND METHODS This is a hospital based retrospective study based on medical records from the period of January 2013 to December 2015. Thyroid hormones were evaluated by RIA for T3 & T4 and IRMA for TSH, kits supplied by BRIT, Mumbai. RESULTS 2322 study subjects comprised of males 403 and 1919 females. Thyroid dysfunction categorized was as hypothyroidism, subclinical hypothyroidism, hyperthyroidism and Subclinical hyperthyroidism as per reference values for thyroid hormones. Prevalence of thyroid dysfunction was 43.7% in females and females were more affected than males. Hypothyroidism 15.80% and Subclinical hypothyroidism 21.40% were higher than hyperthyroidism 3.91% and subclinical hyperthyroidism 2.58% subjects aged 30-45 years had a higher prevalence. Euthyroid subjects constituted 56.28%. CONCLUSION Study revealed high prevalence of abnormal thyroid function. Females and elderly are more susceptible. Since untreated thyroid disease leads to significant morbidity, public awareness in the context of primary care setting will be valuable.
THYROID DISORDERS AMONG PATIENTS VISITING TERTIARY HEALTH CARE CENTRE IN EASTERN UTTAR PRADESH.
International Journal of Advanced Research (IJAR), 2019
Background: Thyroid hormone abnormalities are the commonest endocrine disorder in India, but there is scarcity of data on the status of thyroid disorders in this part of eastern Uttar Pradesh of India. Objective: To determine the prevalence, clinical profile and associated co-morbidities of thyroid disorders in Prayagraj and nearby areas. Methods and Materials: A hospital based, cross sectional study was conducted at MLN Medical College and Swaroop Rani Nehru Hospital, Prayagraj. Patients visiting the medicine out-patient department (OPD) and in-patient department (IPD) were included if they had clinical suspicion of thyroid dysfunction. Clinical features of the 783 recruited patients were noted. Thyroid profile consisting of Tri-iodothyronin (T3), Thyroxin (T4) and Thyroid stimulating hormone (TSH) levels were tested in all. Investigations were also carried out to look for the co-morbidities associated with hypothyroidism. Results: Out of the 783 patients tested, 626 were females and 157 were males. 190 patients were found to have thyroid function abnormalities, 29 having subclinical hypothyroidism, 145 were overt hypothyroidism and 16 having hyperthyroidism. There was a high prevalence of goitre (43.75%) among patients of hyperthyroidism. The clinical feature of patients with hypo and hyperthyroidism was similar to other reported studies. Fatigue (70.38%) being the most common symptom in patients of overt hypothyroidism while palpitation (75%) was the most common presentation in patients of hyperthyroidism. A host of co-morbidities was observed along with thyroid dysfunction; anemia (n=47) was the most common followed by type 2 diabetes mellitus (n=33). Conclusion: Higher prevalence of hypothyroidism was observed in patients (especially females) in their third to fourth decade of life. Goiter is more frequent finding in patients of hyperthyroidism. The findings also support the indication of thyroid hormone screening during third decade of life and afterwards.