Playing polo during mitosis: PLK1 takes the lead (original) (raw)

Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1)

Jiabin Tang

Proceedings of the National Academy of Sciences, 2006

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B23/Nucleophosmin Serine 4 Phosphorylation Mediates Mitotic Functions of Polo-like Kinase 1

Steven Pelech

Journal of Biological Chemistry, 2004

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Regulatory functional territory of PLK-1 and their substrates beyond mitosis

Garima Sharma

Oncotarget, 2015

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Regulation of cell cycle checkpoints by polo-like kinases

Marietta Y. W. T. Lee

Oncogene, 2005

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Ubiquitylation-dependent localization of PLK1 in mitosis

Izabela Sumara

Nature Cell Biology, 2013

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Use of the Novel Plk1 Inhibitor ZK-Thiazolidinone to Elucidate Functions of Plk1 in Early and Late Stages of Mitosis

D. Mumberg

Molecular Biology of the Cell, 2007

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Ectopic Expression of Plk1 Leads to Activation of the Spindle Checkpoint

Jiabin Tang

Cell Cycle, 2006

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The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1

Martin Steegmaier

Current Biology, 2007

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Co-inhibition of polo-like kinase 1 and aurora kinases promotes mitotic catastrophe

Peizhang Zhou

Oncotarget, 2015

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The mitotic roles of Polo-like kinase

Alvaro Tavares

Journal of cell …, 2001

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The Polo Box Is Required for Multiple Functions of Plx1 in Mitosis

Junjun Liu

Journal of Biological Chemistry, 2004

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Polo-like kinases: a team that plays throughout mitosis

Alvaro Tavares

Genes & Development, 2006

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Roles of Polo-like Kinase 1 in the Assembly of Functional Mitotic Spindles

Consuelo García-de-la-Torre

Current Biology, 2004

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Editorial: Novel Insights Into the Multifaceted Mitotic Kinases

Sabine Elowe

Frontiers in Cell and Developmental Biology

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Genetic depletion of Polo-like kinase 1 leads to embryonic lethality due to mitotic aberrancies

Beatriz Escobar

Inside the Cell, 2015

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Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora

Eunice Chan

Chromosoma, 2008

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Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis

Henk Janssen

Journal of Biological Chemistry, 2004

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Polo kinase: the choreographer of the mitotic stage?

Alvaro Tavares

The Journal of cell biology, 2006

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A PIM-CHK1 signaling pathway regulates PLK1 phosphorylation and function during mitosis

Christine Didier

Journal of cell science, 2018

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Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1

Ruediger Neef

Nature Cell Biology, 2007

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CDK-dependent potentiation of MPS1 kinase activity is essential to the mitotic checkpoint

Sabrina Mel

Current biology : CB, 2012

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Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle

Uttam Surana

Nature Cell Biology, 2008

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The polo-like kinase 1 regulates CDC25B-dependent mitosis entry

Jean-Pierre Bouché

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009

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PKA and MPF-Activated Polo-like Kinase Regulate Anaphase-Promoting Complex Activity and Mitosis Progression

Stuart Tugendreich

Molecular Cell, 1998

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Kinetochore phosphatases suppress autonomous Polo-like kinase 1 activity to control the mitotic checkpoint

Marília Cordeiro

Journal of Cell Biology, 2020

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Xenopus Polo-like kinase Plx1: a multifunctional mitotic kinase

Junjun Liu

Oncogene, 2005

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Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization

Guillermo de Cárcer

Proceedings of the National Academy of Sciences, 2007

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Faculty of 1000 evaluation for The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation

Kevin Hardwick

F1000 - Post-publication peer review of the biomedical literature

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Hornerin mediates phosphorylation of the polo-box domain in Plk1 by Chk1 to induce death in mitosis

Chang-Young Jang

Cell Death & Differentiation

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Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis

Judith Steen

Molecular Biology of the Cell, 2012

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Complex formation of Plk1 and INCENP required for metaphase–anaphase transition

Tohru Kiyono, Hidemasa Goto

Nature Cell Biology, 2006

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Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk

Tallessyn Z Grenfell-Lee

Proceedings of the National Academy of Sciences of the United States of America, 1998

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