Prevalence and Socio-Demographic Factors of Bipolar Mood Disorders in Children and Adolescents: Identifying the Principal Predictors (original) (raw)

Research Paper Prevalence and Socio-Demographic Factors of Bipolar Mood Disorders in Children and Adolescents: Identifying the Principal Predictors

Iranian Rehabilitation Journal (IRJ), 2022

Our objective is to measure the prevalence of bipolar mood disorder (BMD) in Iranian children and adolescents and its comorbidity with psychiatric disorders. Also, the main purpose of this study is to characterize the main risk factors for BMD in children and adolescents. Methods: This is an analytical cross-sectional study. In a community-based study, we sampled 1000 children and adolescents from the age of 6 to 18 years in each province via the multistage cluster sampling method. The total valid sample size reached 29 812 cases. The instructed clinical psychologists completed the Persian version of the kiddie schedule for affective disorders and schizophrenia present and lifetime version (K-SADS-PL). Furthermore, the demographic data were obtained. To analyze the data, descriptive statistics, multinomial, and multiple logistic regressions were utilized to evaluate the relationships. Results: The total prevalence rates for BMD were 0.29%; it was 0.26% in males and 0.29% in females. BMD rates were larger in children and adolescents whose mothers had an occupation. Also, after controlling the effective variables (sex and age), location (rural or urban), the father's education, and the psychiatric hospitalization of the mother or the father, none predicted BMD significantly. Moreover, patients with comorbidities showed a superior prevalence compared to those without comorbidities, ranging from 1.96% for posttraumatic stress disorder to 39.22% for the oppositional defiant disorder. Conclusion: BMD was more prevalent among women. The gender or the father's education level was not the risk factor for BMD symptoms. Several factors, such as maternal education and maternal job were also important for the prevalence of BMD symptoms.

Socio-demographic and Clinical Characteristics of 113 Adolescents with Bipolar Disorder: An Inpatient Sample from Turkey

Bezmialem Science

Amaç: Pediyatrik bipolar bozukluk (BB) sosyal, akademik ve aile içi işlevsellikte bozulma ile seyreden bir ruh sağlığı bozukluğudur. Toplum sağlığı açısından taşıdığı öneme karşın, literatürde çocuk ve ergenlerde BB klinik görünümlerine ilişkin araştırma sayısı göreceli olarak azdır. Yöntemler: Bir yataklı tedavi ünitesinde BB-1 ve BB-2 tanısı ile izlenen 113 çocuk ve ergen olgunun tedavilerine ilişkin kayıtlar geriye dönük olarak taranmıştır. BB-1 ve BB-2 tanıları DSM-IV-TR kriterleri temel alınarak konulmuştur. Araştırmacılar tarafından oluşturulan sosyo-demografik ve klinik veri formu, her bir olguya ait kayıtların, araştırmacılarca incelenmesi sonucunda elde edilen bilgiler doğrultusunda doldurulmuştur. Bulgular: Çalışmaya toplamda 113 hasta (71 erkek, 42 kız) dahil edilmiştir. Örneklemin ortalama yaşı 16,054±1.23 (13-18) olarak saptanmıştır. BB ortalama başlangıç yaşı 15,04±1,74 (9-17) idi. Olguların %60'ında ilk duygudurum epizodu manik, %27,3'ünde depresif, %10,9'unda karma, ve %1,8'inde hipomanikti. Olguların %23,4'ünün öyküsünde geçmişte intihar girişimi mevcuttu. Olguların % 48,2'si BB başlangıcından önce bir psikiyatri kliniğine başvuruda bulunmuştu. Olguların %27,4'ünde madde/alkol Objective: Pediatric bipolar disorder (BD) is a highly morbid disorder which is associated with impairments in social, academic, and family functioning. Despite its great impact on public health, the literature is scarce regarding the studies examining the clinical phenomenology of BD in children and adolescents. Methods: A retrospective chart review of 113 children and adolescents' files (ages 13-18 years) who were consecutively admitted to our inpatient clinic between March 2012 and November 2014 and diagnosed as having BD type I or BD type II was made. The diagnoses were based on DSM-IV-TR criteria. A sociodemographic and clinical data form was created by the authors and was filled out for each patient by the authors themselves. Results: Totally 113 adolescents (71 male, 42 female) were included in the study. Mean age of the sample was 16.054±1.23 (range=13-18) years. Mean age of onset of BD was 15.04±1.74 (range=9-17) years. The first mood episode was manic in 60% of patients, depressive in 27.3%, mixed in 10.9% and hypomanic in 1.8% of patients. Of the patients, 23.4% had a suicide attempt history, 48.2% had a previous referral to a psychiatry clinic before the onset of BD. History of

Comparison of Demographic and Diagnostic Characteristics of Iranian Inpatients With Bipolar I Disorder to Western Counterparts

Iranian Journal of Psychiatry and Behavioral Sciences, 2015

Background: Patients' characteristics influence the disorders outcome, so it is valuable to compare mood disorders and inpatients' attributes in different large samples. Objectives: This study was designed to assess demographic and diagnostic characteristics of 3000 Iranian inpatient with bipolar disorders. Patients and Methods: We collected the information of demographic, clinical, and therapeutic characteristics of the patients who were hospitalized in Iran Hospital of Psychiatry, a university affiliated hospital in Tehran, during the 5 years from 2006 to 2011. Results: About 66.1% of the subjects were males and 33.9% were females. Iranian patients are characterized by a higher rate of unemployment, being more single, having health insurance and lower rate of divorce and education compared to the other clinical samples. In the majority of the patients, the disorder had begun with manic phase. Conclusions: Clinical and therapeutic features of Iranian patients are different from patients in western countries.

Reliability and validity of the Bipolar Depression Rating Scale on an Iranian sample

Archives of Iranian medicine, 2010

The Bipolar Depression Rating Scale is an instrument to measure depression severity in patients diagnosed with bipolar disorder. This study has reevaluated the psychometric values of the Bipolar Depression Rating Scale through assessing an Iranian sample of patients with bipolar depression. A total of 60 patients (36 males and 24 females) with bipolar depression referred to four medical centers in Tehran, Iran were interviewed with the Structured Clinical Interview for DSM-IV axis I Disorders, Young Mania Rating Scale, center for Epidemiological Studies Depression Scale, and the Bipolar Depression Rating Scale. Internal consistency and inter-rater reliability of the Bipolar Depression Rating Scale, and Pearson's correlation coefficient between the Bipolar Depression Rating Scale and Young Mania Rating Scale/Center for Epidemiological Studies Depression Scale were calculated. The Cronbach's alpha coefficient was 0.81. The Pearson's correlation coefficients of the Bipolar ...

The Persian Bipolar Spectrum Diagnostic Scale and mood disorder questionnaire in screening the patients with bipolar disorder

Arch Iran Med, 2009

Tehran, Iran, in a sample of 181 consecutive outpatients aged 18 -65 years. The used instruments were the Structured Clinical Interview for DSM-IV axis I disorders, the Persian Bipolar Spectrum Diagnostic Scale, the Persian Mood Disorder Questionnaire, and the Scale to Assess Unawareness of Mental Disorder. Results: Most patients were males (58%) and had bipolar I disorder (57%). Other bipolar disorders and major depressive disorder were diagnosed as 5.5% and 21%, respectively. Testretest of the Persian Bipolar Spectrum Diagnostic Scale and Mood Disorder Questionnaire demonstrated a good reliability for both. The sensitivity, specificity, and positive and negative predictive values of the Persian Bipolar Spectrum Diagnostic Scale at the score of 14, were 0.52, 0.79, 0.81, and 0.49, respectively. The sensitivity and specificity of the parallel application of the Persian Bipolar Spectrum Diagnostic Scale and Mood Disorder Questionnaire were 0.76 and 0.67, respectively. Conclusion: The Persian Bipolar Spectrum Diagnostic Scale and Mood Disorder Questionnaire are useful in screening patients with bipolar disorder in clinical psychiatric settings. Parallel use of both tests seems more effective than either alone.

Demographic and Diagnostic Features of 3147 Inpatients With Mood Disorders in Iran

Iranian Journal of Psychiatry and Behavioral Sciences, 2016

Objectives: To assess and compare demographic and diagnostic characteristics of inpatients with mood disorders in Iran. Materials and Methods: We collected the demographic, clinical, and treatment characteristics of patients, who were hospitalized during five years from April 2006 to March 2010, in Iran hospital of psychiatry, a residency training center to evaluate the general clinical picture of the disorder. Results: Overall, 95.3% of subjects had a diagnosis of bipolar I disorder (BID), 2.5% were diagnosed as bipolar II disorder (BIID) and 1.3% and 0.9% met the criteria for major depressive disorder (MDD) and bipolar not otherwise specified (NOS), respectively. Compared to patients with MDD and BIID, the onset of BID was at an earlier age (32.2 ± 1, 34.8 ± 1.5 and 29.9 ± 1.9 years old, respectively, P < 0.001). In addition, a number of admissions, mean duration of each admission and number of treatments with electro-convulsive therapy (ECT) were significantly higher in patients with BID. Conclusions: Bipolar I disorder was the most common diagnosis for inpatients with mood disorders and a more severe course in BID may indicate more severe impairments that would result in more severe disabilities.

Epidemiology of Psychiatric Disorders in Children and Adolescents Aged 6-18 Years in Zanjan Province, Iran (November-February 2016)

Journal of Human Environment and Health Promotion, 2020

Background: Psychiatric disorders in children and adolescents cause numerous issues in adulthood. Epidemiological data could provide a broad understanding of such issues. However, data are scarce regarding the prevalence of these disorders in Iran. The present study aimed to provide detailed evidence on the prevalence of psychiatric disorders among children and adolescents aged 6-18 years in Zanjan province, Iran during November-February 2016. Methods: In this cross-sectional study, 1,039 children and adolescents were selected via multistage cluster random sampling. Data were collected by face-to-face household surveys using the Persian version of kiddie schedule for affective disorders and schizophrenia-present and lifetime version. Results: The overall prevalence of mental disorders in the children and adolescents in Zanjan was 10.6%. Enuresis (4.8%) was the most common psychiatric issue, followed by anxiety disorders (4.5%), behavioral disorders (3.8%), and neurodevelopmental disorders (1.5%), while mood disorders (0.4%) had the lowest prevalence. Moreover, the children in the rural areas were 1.73 times more likely to develop psychiatric disorders compared to their urban peers. Conclusion: According to the results, approximately 18% of the children and adolescents in Zanjan had at least one psychiatric disorder. Our findings could lay the basis for further research and preventive/therapeutic interventions in this regard.

Bipolar disorder incidence between children and adolescents: A brief communication

Background: Bipolar affective disorder is one of most injurious psychiatric diseases, not, rarely leading patient for suicide, and its prevalence keeps increasing worldwide, notably on low and, middle-income countries. For children living in northeast Brazil, extreme social conditions constitute, an environment of special vulnerability. Objective: Here we show that bipolar disorder incidence, between children and adolescents in this Brazilian region increased 34.2% from 2005 to 2014 and, in, the same area and age group, deaths provoked by self-caused injuries also became progressively, greater. Results: According to DATASUS, the Brazilian national databank for public health, information, in the last five years, we observed an increase of Bipolar Disorder incidence rates under, 19 year-old of about 34.2% in the northeast region of Brazil, while the increase for Brazilian general, population was 12.4%. If considered only patients under 10, this number is even greater, of 47.2%. Content of Table 2 shows this disproportion, while comparing the advance of bipolar disorder, morbidity indices nationwide and worldwide. Conclusion: Children living in Brazil's northeast, region are in a condition of extreme social disadvantage, what can be determinant for the recent and, sequential increase of bipolar disorder prevalence and the mortality in this age-group due to suicide, one of possible reflections of untreated mood disorders. For protecting these children is important to, identify the factors which prevent these illnesses and promote resilience for these young people.

Epidemiology of psychiatric disorders in children and adolescents; in Tehran, 2017

Asian journal of psychiatry, 2018

This survey was conducted to investigate the prevalence of various psychiatric disorders among children and adolescents aged 6-18 years in urban areas of Tehran. In the study, which was done with random sampling method, 2095 children and adolescents in the range seniors aged 6-18 years, have been studied and based on Persian version of K-SADS-PL, we reviewed the psychiatric disorders related to them. The overall prevalence of psychiatric disorders in children and adolescents was 28.2%. The most commonly diagnosed disorders were anxiety disorders (21.9%), followed by behavioral disorders (9.6%). According to the results, 28.2% of the children and adolescents in Tehran province had psychiatric disorders, that is with increasing rate, compared with similar studies. Therefore, as a public health policy, the necessary tools for identifying, preventing and treating psychiatric disorders in children and adolescents should be considered in Tehran.