Interleukin-6 Family of Cytokines Induced Activation of Different Functional Sites Expressed by gp130 Transducing Protein (original) (raw)

gp130 Transducing Receptor Cross-linking Is Sufficient to Induce Interleukin-6 Type Responses

Hugues Gascan

Journal of Biological Chemistry, 1996

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Interleukin6Type Cytokinesa

Ravi Rayanade

Annals of The New York Academy of Sciences, 1995

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Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130

Robert Kastelein

Cytokine, 1995

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Studies on the Interleukin-6-type Cytokine Signal Transducer gp130 Reveal a Novel Mechanism of Receptor Activation by Monoclonal Antibodies

Prof. Dr. John Wijdenes

Journal of Biological Chemistry, 2000

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Definition of a Composite Binding Site for gp130 in Human Interleukin-6

Laura Ciapponi

Journal of Biological Chemistry, 1995

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Ligand-specific utilization of the extracellular membrane-proximal region of the gp130-related signalling receptors

Nicos Nicola

Biochemical Journal, 2000

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Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells

Teresita Bellido

Journal of Clinical Investigation, 1996

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Identification of a gp130 Cytokine Receptor Critical Site Involved in Oncostatin M Response

Hugues Gascan

Journal of Biological Chemistry, 2000

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The immunoglobulin-like module of gp130 is required for signaling by interleukin-6, but not by leukemia inhibitory factor

Leecia Angus

Journal of Biological …, 1998

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Dimerization and activation of the common transducing chain (gp130) of the cytokines of the IL-6 family by mAb

Jean-Philippe Gaillard

International …, 1998

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Nuclear Factor k B (NF-k B), Nuclear Factor Interleukin6 (NFIL-6 or C/EBPbeta) and Nuclear Factor Interleukin6beta (NFIL6-beta or C/EBPdelta) are Not Sufficient to Activate the Endogenous Interleukin6 Gene in the Human Breast Carcinoma Cell Line MCF7. Comparative Analysis with MDA-MB-231 Cells, a...

Chiara Costanzo

European Journal of Biochemistry, 1996

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Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors

Prof. Dr. John Wijdenes

Leukemia, 2000

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The Interleukin-6 (IL-6) Partial Antagonist (Q159E,T162P)IL-6 Interacts with the IL-6 Receptor and gp130 but Fails to Induce a Stable Hexameric Receptor Complex

Edouard Nice

Journal of Biological Chemistry, 1996

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Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

Masahiko Hibi

Cell, 1989

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Activation of gp130 signalingin vivo by the IL-6 super-agonist K-7 / D-6 accelerates repopulation of lymphoid organs after irradiation

Francesco Guidi

European Journal of Immunology, 1999

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IL-6-type cytokine signalling through the gp130/JAK/STAT pathway

Behrmann Iris

Biochemical Journal

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In Vitro Reconstitution of Recognition and Activation Complexes between Interleukin-6 and gp130

Thuy Linh

Biochemistry, 2001

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Receptor Recognition Sites of Cytokines Are Organized as Exchangeable Modules. TRANSFER OF THE LEUKEMIA INHIBITORY FACTOR RECEPTOR-BINDING SITE FROM CILIARY NEUROTROPHIC FACTOR TO INTERLEUKIN-6

Hugues Gascan

Journal of Biological Chemistry, 1999

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Soluble interleukin-6 receptor enhanced by oncostatin M induces major changes in gene expression profile of human hepatoma cells

Peter Igaz

Immunology Letters, 2002

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Induction of an interferon-γ Stat3 response in nerve cells by pre-treatment with gp130 cytokines

navjot Kaur

Journal of Neurochemistry, 2003

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GPL, a Novel Cytokine Receptor Related to GP130 and Leukemia Inhibitory Factor Receptor

Hugues Gascan

Journal of Biological Chemistry, 2003

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Multiple Cytokines Inhibit Interleukin-6-Dependent Murine Hybridoma/Plasmacytoma Proliferation

Rainer Prohaska

Cellular Immunology, 1996

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Regulation of interleukin-2 and interleukin-6 production from T-cells: Involvement of interleukin-1 β and transforming growth factor-β

Anders Waage

Cellular Immunology, 1990

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Expression of functional receptors for interleukin-6 by human polymorphonuclear, leukocytes Downregulation by granulocyte-macrophage colony-stimulating factor

Roland Mertelsmann

FEBS Letters, 1991

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Interleukin 6 and its receptor in the immune response and hematopoiesis

Masahiko Hibi

International journal of cell cloning, 1990

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Antitumor effects of recombinant interleukin-6 expressed in eukaryotic cells

Samario Chaitchik, Micha Rabau

Cancer Immunology Immunotherapy, 1993

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Binding and Functional Effects of Transcriptional Factor Sp1 on the Murine Interleukin-6 Promotor

Sergei Gryaznov

Journal of Biological Chemistry, 1996

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Heinrich, P. C. et al. Principles of IL-6-type cytokine signaling and its regulation. Biochem. J. 374, 1-20

Behrmann Iris

Biochemical Journal

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Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

Masahiko Hibi

Proceedings of the National Academy of Sciences, 1991

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Signal Transduction of IL-6, Leukemia-Inhibitory Factor, and Oncostatin M: Structural Receptor Requirements for Signal Attenuation

Behrmann Iris

The Journal of Immunology, 2000

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Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer

J. Scheller

Journal of Leukocyte Biology, 2006

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Regulation of interleukin-2 and interleukin-6 production from T-cells: Involvement of interleukin-1 ? and transforming growth factor-?

Arild Faxvaag

Cellular Immunology, 1990

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Cloning and expression of an alternatively spliced mRNA encoding a soluble form of the human interleukin-6 signal transducer gp130

Klaus Bendtzen

FEBS Letters, 1997

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Gene regulation by interleukin 6

Georges Baffet

Biochimie, 1991

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Can the action of tumor cell immunosuppression factors be overcome?

Kersti Klaamas

Bulletin of Experimental Biology and Medicine, 1992

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