Status of Thyroid Disorders in Central Nepal: A Tertiary Care Hospital Based Study (original) (raw)
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Assessment of Thyroid Disorder in FarWestern Part of Nepal: A Hospital Based Study
Bangladesh Journal of Medical Science, 2012
Objectives: This study was conducted to know the status of thyroid disorder in people of far western region of Nepal.Methods: A total of 808 cases, out of which 133 male and 675 female were included and study was carried out using data retrieved from the register maintained in the Department of Biochemistry of the Nepalgunj Teaching Hospital, Kohalpur, Banke, Nepal, between 1st January, 2011 and 28th February, 2012. The variables collected were age, sex, and thyroid function profile including free T3, free T4 and TSH. The data was analyzed using Excel 2003, R 2.8.0 Statistical Package for the Social Sciences (SPSS) for Windows Version 16.0 (SPSS Inc; Chicago, IL, USA) and the EPI Info 3.5.1 Windows Version. Results: The percentage of thyroid disorders was 33.66% in people of far western region of Nepal. The people were highly affected by overt hyperthyroidism (14.9%) followed by subclinical hyperthyroidism (9.9%). The subclinical hypothyroidism was 7.9% while 1% overt hypot...
Pattern of thyroid disorders in people from central Nepal : A Hospital based
2017
Metabolic disorders including thyroid dysfunction is increasing problem throughout the world. We aim to observe the pattern of thyroid disorder among people attending one of the hospitals in the central development region of Nepal. An observational study was conducted among 290 individuals who attended the Medical unit of Shree Puspanjali Hospital Pvt. Ltd, Bharatpur-10, Nepal between May 2016 and August 2016. Socio-demographic characteristics, clinical characteristics and laboratory data (from thyroid function test) were collected. Data were analyzed using IBM-SPSS 20.0 and descriptive and inferential analysis was performed. Of the 290 individuals, 215 (74.23%) had thyroid disorders among which hypothyroidism was the most common disorder (187, 87.0%) followed by hyperthyroidism (24, 11.2%) and subclinical hypothyroidism (4, 1.9%). Majorities (261, 90%) of the participants were female and so were those with thyroid disorders (196, 91.2%). The mean age of the participating individual...
Thyroid dysfunction in eastern Nepal
PubMed, 2002
Nepal lies in an area of endemic iodine deficiency. Thyroid dysfunction, along with a higher than average prevalence of goiter, is a major public health problem among the local population. The present study was undertaken to investigate the prevalence of thyroid dysfunction among the hill and terai (low land) castes of eastern Nepal that attended the thyroid clinic at the BP Koirala Institute of Health Sciences (BPKIHS), Dharan. A total of 599 cases were studied during a single year. The distribution of hyperthyroid and hypothyroidism was 13.68% and 17.19% respectively. The majority of the thyroid dysfunction was seen in the 21-40 year age group. The prevalence of hypothyroidism was slightly higher among terai castes (17.66%) when compared with hill castes (15.17%). There was a similar distribution of thyroid dysfunction among the male and female populations of the goitrous subjects (n=157), most were euthyroid (58.59%); hyperthyroidism affected (27.38%). Since, it was a hospital-based study, the prevalence of thyroid dysfunction may not be applicable to the general population. Extensive field-based countrywide epidemiological studies are necessary to provide data about thyroid dysfunction in the community.
A prevalence of thyroid dysfunction in Kathmandu University Hospital, Nepal
Thyroid dysfunction is one of the most commonly encountered endocrine abnormalities. The screening of thyroid dysfunction is recommended in Nepal with its high risk population. Many factors are responsible for exacerbating the thyroid dysfunction in the context of Nepal. Therefore, this study was designed to assess the prevalence of thyroid dysfunction in Dhulikhel Hospital-Kathmandu University Hospital (DH-KUH). In this hospital based retrospective study, 825 subjects (resident of Kavre) that were subjected to thyroid function test panel (free tri-iodothyronine, free thyroxine and thyroid stimulating hormone) were enrolled and the thyroid dysfunction was stratified as hypothyroidism, subclinical hypothyroidism, hyperthyroidism, subclinical hyperthyroidism with reference to hormonal levels. Among 825 subjects, the prevalence of thyroid dysfunction was 25%. Females had more thyroid dysfunction than males. Hypothyroidism (8%) and subclinical hypothyroidism (8%) had higher prevalence c...
Pattern of thyroid disorders in people from central Nepal: A Hospital based study
Metabolic disorders including thyroid dysfunction is increasing problem throughout the world. We aim to observe the pattern of thyroid disorder among people attending one of the hospitals in the central development region of Nepal. An observational study was conducted among 290 individuals who attended the Medical unit . Socio-demographic characteristics, clinical characteristics and laboratory data (from thyroid function test) were collected. Data were analyzed using IBM-SPSS 20.0 and descriptive and inferential analysis was performed. Of the 290 individuals, 215 (74.23%) had thyroid disorders among which hypothyroidism was the most common disorder (187, 87.0%) followed by hyperthyroidism (24, 11.2%) and subclinical hypothyroidism (4, 1.9%). Majorities (261, 90%) of the participants were female and so were those with thyroid disorders (196, 91.2%). The mean age of the participating individuals was 45.9±1.3 years. Hypertension (49, 16.9%) was the commonest co-morbid condition among the participants (30, 10.3%) but diabetes (p=0.004) and dyslipidemia (p=0.002) were significantly associated with thyroid disorder. In conclusion, hypothyroidism was the most common thyroid disorders and female were at the most vulnerable group. This is a single hospital based study; therefore, it is not sufficient to generalize the thyroid disorder in whole population.
Spectrum of thyroid dysfunction in patients visiting Kantipur Hospital, Kathmandu, Nepal
Mymensingh medical journal : MMJ, 2013
Thyroid disorder is most common endocrine abnormality in the general population and its prevalence increases with age. The screening of thyroid disorder is advised in high risk population. This hospital based cross-sectional study was conducted in Department of Biochemistry, Kantipur Hospital, Kathmandu, Nepal. Patients having complains of thyroid disease from February 2010 to January 2011 were enrolled in this study. Thyroid parameters such as FT3, FT4 and TSH were measured by ELISA technique. Among total 472 subjects 393(83.27%) were female whereas 79(16.73%) were male. The prevalence of thyroid dysfunction was 36.0% (n=170). The different patterns of thyroid dysfunction in Kathmandu valley were: hypothyroid (11.6%), subclinical hypothyroid (16.9%), hyperthyroid (4.0%), and subclinical hyperthyroid (3.6%) respectively. Subjects having all thyroid parameters normal i.e. euthyroid were 63.9%. In conclusion, this study reveals a higher prevalence of thyroid dysfunction in Kathmandu r...
Asian Pacific Journal of Tropical Disease, 2013
Risk assessment, Thyroid function, Nepal Objective: To know the status of thyroid disorder in population of far western region of Nepal. Methods: A total of 808 cases (133 men and 675 non pregnant women) were included and study was carried out using data retrieved from the register maintained in the Department of Biochemistry of the Nepalgunj Teaching Hospital between 1st January, 2011 and 28th February, 2012. The variables collected were age, sex, and thyroid function profile including free T3, free T4 and TSH. Results: The percentage of thyroid disorders was 33.66% in far western region of Nepal. The people were highly affected by overt hyperthyroidism (14.9%) followed by subclinical hyperthyroidism (9.9%). The subclinical hypothyroidism was 7.9% while 1% overt hypothyroidism only in a far western region of Nepal. Females were highly affected by overt hyperthyroidism (17.8%), followed by subclinical hyperthyroidism (11.9%). A total of 5.9% females were affected by subclinical hypothyroidism while only 1.2% by overt hypothyroidism. Males were affected only by subclinical hypothyroidism (18.0%) in this present study. High number of total thyroid dysfunction was observed in 21 to 40 years of age groups, followed by 41 to 60 years of age groups. Less than 40 years people were having 1.03, 0.99, 2.51 and 1.15 times risk of developing overt hyperthyroidism, subclinical hyperthyroidism, overt hypothyroidism and subclinical hyperthyroidism respectively compared to greater than 40. Female were having 0.29 times risk of developing subclinical hyperthyroidism compared to male. But overt hyperthyroidism, subclinical hyperthyroidism and overt hypothyroidism female were having more risk of developing compared to male. Conclusions: The thyroid disorder, especially overt hyperthyroidism (14.9%) and subclinical hyperthyroidism (9.9%) was high. Further studies are required to characterize the reasons for this high prevalence.
Prevalence of Thyroid Dysfunction in Community of Duwakot, Bhaktapur
Journal of Pathology of Nepal
Background: Thyroid dysfunction is one of the major public health problems in the Nepalese community and of the common endocrine disorders diagnosed in community primary health care centres. The aim of this study is to analyze the prevalence of Thyroid dysfunction in Duwakot, Nepal. Materials and Methods: All the patients from Duwakot community who presented with the history of weight gain with tiredness and weight loss with palpitation were subjected to thyroid function test free triiodothyronine, free thyroxine and thyroid stimulating hormone. Results: Thyroid dysfunction was found in 26% with M:F ratio of 1:5. Subclinical hypothyroidism 62 (11.44%) was the most prevalent one followed by Primary hypothyroidism 48 (8.85%), primary hyperthyroidism 16 (2.95%) and subclinical hyperthyroidism 15 (2.76%). Conclusion: Thyroid dysfuntion has been observed despite of nationwide program regarding supplementation of micronutrient iodised salt.
Medical Journal of Shree Birendra Hospital, 2017
Introduction: Thyroid disorder is second most common endocrine disorder after diabetes in the world. The burden of thyroid diseases in the general population is enormous especially in females. The aim of this paper is to study the prevalence of thyroid disorders among population of Far Western Region. Methods: The present work was conducted to study the ethnic differences in the prevalence of thyroid disorders in patients who attended the Life Care Diagnostics and Research Center Pvt. Ltd. Dhangadhi. Total of 1000 patients suspected with thyroid disorders were enrolled in this study. The incidence of thyroid disorders and its relationship with the different ethnic, age groups and gender were investigated. Results: Out of 1000 patients with suspected thyroid dysfunction, 65.8 % were euthyroid followed by 13.8 % of patients having subclinical hypothyroidism, 9.5% hyperthyroidism and 7.9 % hypothyroidism. The incidence subclinical hyperthyroidism 3.0% was lowest. Hypothyroidism was the most common thyroid disorders among ethnic groups, Chhetri 37.97 % and Brahmin 40.57 %. In addition, females were most affected among the population. Conclusion: The prevalence of thyroid disorders in Far western population showed difference among different ethnic group. Public awareness of thyroid disorders and their potential complications could lead to improved diagnostic and therapeutic facilities.anti-snake venom.
Status of Thyroid Function among Patients of National Medical College and Teaching Hospital
Med Phoenix
Background: Thyroid dysfunction is one of the most common endocrinopathies after Diabetes Mellitus. Thyroid dysfunction is defined as the alteration in Thyroid Stimulating Hormone (TSH) with normal or abnormal thyroid hormones. Nepalese population have a high risk for thyroid dysfunction with a high prevalence of iodine deficiency. Objective: To study the prevalence of thyroid dysfunction among the patients visiting National Medical College, Birgunj, Nepal for checkup and suggested to assess thyroid function. Materials and Methods: The hospital-based study was conducted in Central Laboratory, National Medical College and Teaching Hospital (NMCTH), Birgunj in collaboration with the Department of Biochemistry. Total 7040 patients visiting Central Laboratory for thyroid function assessment were included in the study between July 2017 to December 2019. The venous blood sample was collected and serum-free triiodothyronine(fT3), free tetraiodothyronine(fT4) and thyroid stimulating hormone...