The disease X: waiting for the next pandemic (original) (raw)
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Post COVID-19: a solution scan of options for preventing future zoonotic epidemics
Biological Reviews, 2021
The crisis generated by the emergence and pandemic spread of COVID-19 has thrown into the global spotlight the dangers associated with novel diseases, as well as the key role of animals, especially wild animals, as potential sources of pathogens to humans. There is a widespread demand for a new relationship with wild and domestic animals, including suggested bans on hunting, wildlife trade, wet markets or consumption of wild animals. However, such policies risk ignoring essential elements of the problem as well as alienating and increasing hardship for local
COVID-19: animals, veterinary and zoonotic links
Veterinary Quarterly, 2020
Coronavirus disease 2019 (COVID-19), has spread over 210 countries and territories beyond China shortly. On February 29, 2020, the World Health Organization (WHO) denoted it in a high-risk category, and on March 11, 2020, this virus was designated pandemic, after its declaration being a Public Health International Emergency on January 30, 2020. World over high efforts are being made to counter and contain this virus. The COVID-19 outbreak once again proves the potential of the animal-human interface to act as the primary source of emerging zoonotic diseases. Even though the circumstantial evidence suggests the possibility of an initial zoonotic emergence, it is too early to confirm the role of intermediate hosts such as snakes, pangolins, turtles, and other wild animals in the origin of SARS-CoV-2, in addition to bats, the natural hosts of multiple coronaviruses such as SARS-CoV and MERS-CoV. The lessons learned from past episodes of MERS-CoV and SARS-CoV are being exploited to retort this virus. Best efforts are being taken up by worldwide nations to implement effective diagnosis, strict vigilance, heightened surveillance, and monitoring, along with adopting appropriate preventive and control strategies. Identifying the possible zoonotic emergence and the exact mechanism responsible for its initial transmission will help us to design and implement appropriate preventive barriers against the further transmission of SARS-CoV-2. This review discusses in brief about the COVID-19/SARS-CoV-2 with a particular focus on the role of animals, the veterinary and associated zoonotic links along with prevention and control strategies based on One-health approaches.
Human activities and zoonotic epidemics: a two-way relationship. The case of the COVID-19 pandemic
Global Sustainability , 2022
Non-technical summary. Humans have the tendency to damage the natural environment in many ways. Deforestation and conversion of forests for residential, industrial development, and expansion of agricultural crops, as well as the burning of fossil fuels, are some activities that disrupt natural ecosystems and wildlife and contribute to climate change. As a result, the life cycles of pathogens and intermediate hosts (insects, rodents, mammals) as well as biodiversity are affected. Through these activities, humans meet wild animals that transmit pathogens, resulting in their infection by zoonoses and causing epidemics-pandemics, the effects of which have as their final recipient himself and his activities. Technical summary. This article aims to highlight the two-way relationship between those human activities and the occurrence of epidemics-pandemics. We will try to elaborate this twoway relationship, through the overview of the current pandemic (origin of SARS-CoV-2, modes of transmission, clinical picture of the disease of COVID-19, influence of weather and air pollution on prevalence and mortality, pandemic effects, and treatments). They are used as primary sources, scientific articles, literature, websites, and databases (Supplementary appendix) to analyze factors involved in the occurrence and transmission of zoonotic diseases in humans (Ebola, influenza, Lyme disease, dengue fever, cholera, AIDS/HIV, SARS-CoV, MERS-CoV). The present paper concluded that humanity today faces two major challenges: controlling the COVID-19 pandemic and minimizing the risk of a new global health crisis occurring in the future. The first can be achieved through equitable access to vaccines and treatments for all people. The second needs the global community to make a great change and start protecting the natural environment and its ecosystems through the adoption of prevention policies. Summary of social media. Two-way relationship between human activities and epidemics highlighted, through review of the COVID-19 pandemic.
COVID – 19: Basis for United Future Global Response to a Pandemic
The Impact Of COVID19 On The International Education System, 2020
This chapter focuses on the link between humans – animal interaction and emergence of global pandemics. Influenza virus to which humans have no immunity, has potential to cause a pandemic when it acquires the ability to cause sustained human to human transmission which lead to community wide outbreaks. Transmissibility and severity are the two most critical factors that determine the effect of an epidemic. In the history of pandemics, neither the 2009 pandemic influenza A(H1N1) virus ([H1N1]pdm09) pandemic or the severe acute respiratory syndrome coronavirus (SARS – COV) or the Middle East respiratory syndrome coronavirus (MERS – CoV) epidemics, had the combination of both high transmissibility and severity, like COVID – 19, hence it has been declared a Public Health Emergency of International Concern (PHEIC). It is clear COVID – 19 pandemic is an unprecedented danger which does not differentiate on any basis be it borders, ethnicities, disability status, age or gender. This justifi...
Wildlife Trade, Pandemics and the Law: Fighting This Year's Virus with Last Year's Law
Legal Atlas, 2021
As of January 22, 2021, over 97M human cases and 2.1M deaths have been reported globally due to COVID-19 caused by SARS-CoV-2. Both figures are almost double what they were just two months prior; with infection rates and mortality still climbing. The international response has of course been strong with significant attention being given to how we can change international agreements like UNTOC and CITES. There has also been talk of prohibiting wildlife trade altogether and pursuing better management of natural resources. But zoonotic diseases are not new, and most countries have some policies in place to manage zoonotic disease risks or impacts but require re-examination in light of COVID-19. This report therefore takes a critical look at the national legal context, sampling 38 jurisdictions and asking; what have nations already done with their laws that support the monitoring and prevention of disease emergence that comes from wildlife? In particular, it examines how ten different areas of law respond to this need. In addition to the main findings, the authors provide a summary of the legal challenges and the many opportunities for immediate action.
Epidemiology, Zoonotic and Reverse Zoonotic Potential of COVID-19
SARS-CoV-2 Origin and COVID-19 Pandemic Across the Globe, 2021
The demographic patterns of COVID-19 spread can provide clues to develop roadmaps for devising better prevention and control. It is high time to analyze and re-evaluate the zoonotic/reverse zoonotic spread of SARS-CoV-2 globally. To this end, lessons from epidemiology and associated determinants from previous outbreaks of SARS-CoV-1 and MERS need to be cultured and re-visited. Ways to minimize the rates of infection and promote the well-being of the masses need urgent attention owing to the subsequent waves of the global pandemic in most countries. Efforts are being directed for the provision of efficient and cost-effective diagnostics, prophylaxis and therapeutic options for COVID-19. The chapter provides insights, suggesting a potential roadmap for efficiently preventing the future outbreaks of COVID-19, based on the tools of epidemiology, transmission probabilities and public health safety concerns.
International Journal of General Medicine
The re-emergence of COVID-19 has sparked controversy around its zoonotic origin, management strategies, risks posed by the virus, and the severity of reinfection. While it is widely accepted that the virus originated from animals, the exact source and transmission pathway remain unclear. This has led to debates regarding the regulation of wildlife markets and trade, as well as the need for more robust surveillance and monitoring systems. Hence, the objective of this review is to provide a brief overview of the disease's biology, preventative strategies, risk factors, degree of reinfection, and epidemiological profile. It offers a thorough examination of the disease's root cause, potential zoonotic transmission, and the most recent preventive measures, like vaccines. In terms of management, there is ongoing debate about the most effective strategies to mitigate the spread of the virus. While public health measures such as social distancing and mask-wearing have been widely implemented, there are differing opinions on the effectiveness of lockdowns and restrictions on public movement. The risks posed by COVID-19 are also a topic of debate, with some arguing that the virus is relatively low-risk for the majority of the population while others highlight the potential for severe illness, particularly among vulnerable populations such as the elderly or those with underlying health conditions. Finally, the possibility of reinfection has raised concerns about the longevity of immunity following infection or vaccination. While some studies have suggested that reinfection may be possible and potentially more severe, the overall risk remains uncertain and further research is needed to fully understand the implications of reinfection.