Applications of Synthetic Biology in Microbial Biotechnology (original) (raw)

2010, Journal of Biomedicine and Biotechnology

Recent advances in synthetic biology have greatly expanded the capacity to improve pathway performance and cellular phenotype. The design, use, and importation of constructed genetic control elements, optimized genes, and functional genetic circuits can be used to modulate the function of metabolic pathways. The modularity and hierarchy of parts, devices, systems, and chassis provide a framework for studying and controlling cellular functions. Moreover, synthetic biology provides an interface where protein engineering, directed evolution, DNA synthesis, and in silico