141st ENMC International Workshop Inaugural Meeting of the EURO-Laminopathies Project Nuclear Envelope-linked Rare Human Diseases: From Molecular Pathophysiology towards Clinical Applications 10–12 March 2006, Naarden, The Netherlands (original) (raw)

The EURO-Laminopathies project, initiated at a workshop in Naarden, focuses on elucidating the molecular mechanisms underlying laminopathies—rare diseases caused by mutations in nuclear envelope protein-coding genes. With contributions from multiple countries, the consortium aims to identify diagnostic markers and therapeutic targets to enhance treatment outcomes for patients affected by these disorders. Insights gained from clinical trials and research into disease mechanisms highlight the complexity of laminopathies and propose new avenues for intervention, emphasizing the need for individualized therapies based on the specific mutations involved.