Bioceramic Sealants: A Review (original) (raw)
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Bioceramic-Based Root Canal Sealers: A Review
Bioceramic-based root canal sealers are considered to be an advantageous technology in endodontics. The aim of this review was to consider laboratory experiments and clinical studies of these sealers. An extensive search of the endodontic literature was made to identify publications related to bioceramic-based root canal sealers. The outcome of laboratory and clinical studies on the biological and physical properties of bioceramic-based sealers along with comparative studies with other sealers was assessed. Several studies were evaluated covering different properties of bioceramic-based sealers including physical properties, biocompatibility, sealing ability, adhesion, solubility, and antibacterial efficacy. Bioceramic-based sealers were found to be biocompatible and comparable to other commercial sealers. The clinical outcomes associated with the use of bioceramic-based root canal sealers are not established in the literature.
COMPARISON OF THREE BIOCERAMIC SEALERS IN TERMS OF DENTINAL SEALING ABILITY IN THE ROOT CANAL
International Journal of Applied Pharmaceutics , 2020
Objective: The main objective of endodontic treatment is to prevent further infection or reinfection by eliminating microorganisms within the root canal system. Proper endodontic treatment could prevent apical and coronal penetration of fluids and microorganisms. Endodontic sealer is vital components of root canal obturation to establish a fluid-tight seal. Bioceramic-based root canal sealers are considered to be an advantageous technology in endodontics and have been found to be both biocompatible and comparable to other commercial sealers. The aim of this study was to compare the adhesion of three bioceramic sealers within the root canal system. Methods: Endodontically treated teeth were obturated using three types of bioceramic sealers and then divided into three groups. Specimens were then observed using a scanning electron microscope, and the attachment distance was measured using ImageJ. Results: The three groups exhibited were statistically significant differences (p<0.05) in dentinal sealing ability. Calcium phosphate silicate-based sealer showed the highest sealing ability, followed by pure tricalcium silicate-based bioceramic sealers and then tricalcium silicate and resin-based bioceramic sealers. Conclusion: The sealing ability of calcium phosphate silicate-based sealer is superior to that of both pure tricalcium silicate-based and tricalcium silicate-and resin-based sealer.
Bioceramics as Root Canal Sealers: A Review
2020
Epoxy resin-based sealers which are currently widely used have limitations, including possible mutagenicity, cytotoxicity, inflammatory response, and hydrophobicity. Recently, bioceramic-based sealers containing calcium silicate and calcium phosphate attracted considerable attention because of their physical and biological properties such as their alkaline pH, chemical stability within the biological environment, and lack of shrinkage. Bioceramic materials containing calcium phosphate, enhances the setting properties of bioceramics and results in a chemical composition and crystalline structure similar to tooth and bone apatite materials, thereby improving sealer-to-root dentin bonding. This review focuses on advantages, mechanism of action,classification and detailed insight into individual bioceramic sealers currently used along with their properties.
Bioactivity Potential of Bioceramic-Based Root Canal Sealers: A Scoping Review
Life
Introduction: Bioceramic-based root canal sealers are novel materials with a bioactivity potential that stands out compared with conventional root canal sealers. However, the term bioactivity may be overused and is often misunderstood. Hence, the objective of this study was to synthesize and map key concepts related to the bioactivity analysis of bioceramic-based root canal sealers. Methods: The present scoping review is reported in accordance with the PRISMA-ScR Statement and is registered in the Open Science Framework. Two blinded reviewers carried out a comprehensive search in six databases up to January 10th, 2022: MEDLINE, Scopus, Embase, Web of Science, Cochrane Library, and Lilacs/BBO. Eligibility was considered for in vitro and in vivo studies that evaluated the bioactivity potential of bioceramic-based root canal sealers. Results: A total of 53 studies were included in the qualitative synthesis. In vitro bioactivity was evaluated through the mineralization potential, format...
2020
BACKGROUND: Recently, new calcium silicate bioceramic sealers were introduced to the market. The selection of root canal sealers should not only be based on the different physical parameters but also on local biocompatibility and tissue tolerance. AIM: This study aimed to evaluate and compare the in-vivo biocompatibility of a BioRoot RCS in parallel to MTA Fillapex and AH Plus sealers. METHODS: Polyethylene tubes containing the freshly mixed test materials were implanted in the subcutaneous tissue of 32 Wistar rats. Empty tubes served as negative controls. After 7, 14, 30, and 60 days, the animals were sacrificed, and the implants with surrounding tissues were processed for routine histological analysis. Histological sections were analyzed under light microscopy. The tissue response was determined by the inflammatory cell infiltration intensity and the fibrous capsule thickness. RESULTS: Results revealed a statistically significant decrease of the inflammation intensity by time within each group for all tested sealers and control. A well-defined thin capsule was observed for all tested sealers at 60 days. CONCLUSION: BioRoot RCS exhibited rapid recovery of inflammation similar to controls. Thus, within the limitations of this study, it can be considered a biocompatible sealer with acceptable tissue tolerance.
Biocompatibility and bioactive potential of the NeoMTA Plus endodontic bioceramic-based sealer
2021
Objectives This study evaluated the biocompatibility and bioactive potential of NeoMTA Plus mixed as a root canal sealer in comparison with MTA Fillapex. Materials and Methods Polyethylene tubes filled with NeoMTA Plus (n = 20), MTA Fillapex (n = 20), or nothing (control group, CG; n = 20) were inserted into the connective tissue in the dorsal subcutaneous layer of rats. After 7, 15, 30 and 60 days, the specimens were processed for paraffin embedding. The capsule thickness, collagen content, and number of inflammatory cells (ICs) and interleukin-6 (IL-6) immunolabeled cells were measured. von Kossa-positive structures were evaluated and unstained sections were analyzed under polarized light. Two-way analysis of variance was performed, followed by the post hoc Tukey test (p ≤ 0.05). Results At 7 days, the capsules around NeoMTA Plus and MTA Fillapex had more ICs and IL-6-immunostained cells than the CG. However, at 60 days, there was no significant difference in the IC number between...
Journal of Liaquat University of Medical & Health Sciences
June-December 2018. Fresh extracted 32 teeth were included and their crowns were sectioned at Cemento-Enamel Junction/service to obtain 12mm standard root length. The access cavity was gained using endodontic instruments. The teeth were divided into two groups, in Group A (n=16) MTA Bioceramic and in Group B (n=16) AH Plus was used as root canal sealers by single cone obturation technique. The obturated specimens were stored in humid conditions for one week. Analysis was done using SPSS version 20. RESULTS: Mean and standard deviation of dye leakage for Bioceramic were 2.25±0.9 whereas for AH Plus was significantly lower, 1.19±0.75. Teeth included in Group A were central incisors 37.5%, lateral incisors 18.8%, canine 12.5%, lower first premolars 12.5% and second premolars 6.3%, whereas Group B consisted of central incisors 18.8%, lateral incisors 12.5 %, canine 12.5%, lower first premolars 18.8 % and second premolars 6.3%. Dye leakage was higher in Group A compared to Group B with a significant P-value < 0.001. CONCLUSION: It can be concluded based on this study that AH Plus offers a better apical seal as compared to Bioceramic-based MTA Fillapex sealers.
IP innovative publication pvt. ltd, 2019
Abstract Aim: The present in-vitro study evaluated the influence of different organic and inorganic root canal irrigants used during chemomechanical preparation on the push-out bond strength of an Epoxy-resin based AH Plus sealer and a Bioceramic Endosequence BC sealer. Materials and Methods: Eighty extracted permanent human mandibular single rooted premolar teeth were used and randomly assigned to four major groups [according to irrigation protocol using sodium hypochlorite (NaOCl) with MTAD (mixture of tetracycline, acid and detergent) or ethylenediaminetetraacetic acid (EDTA) or phosphoric acid or normal saline (NS) as control group]. The root canals were instrumented using rotary nickel-titanium Hyflex® CM file system to size 30/0.06 taper, at the working length, as final shaping and finishing file, following different irrigation protocols, as per group allocation. The samples were further subdivided into two groups, with ten samples each (n=10), based on endodontic sealer; roots were obturated with gutta-percha and test sealers (AH-Plus or Endosequence Bioceramic sealer). The teeth were decoronated and obtained samples of eighty obturated roots of eight groups were cut to obtain 2mm thick coronal root slices (10 root section in each group), using hard tissue microtome. Bond strength of sealers was then measured by subjecting each root section to a compressive load via Instron Universal testing machine. The data were tabulated and statistically analyzed using analysis of variance (ANOVA) and Tukey’s HSD along with Bonferroni’s post-hoc test and level of significance set at a p value<0.05. Results: The highest mean push-out bond strength of 5.38 MPa for AH Plus sealer was obtained in Group 2A followed by 3.94 MPa for Endosequence BC sealer (Group 2B), when phosphoric acid was used as chelating agent. However, mean bond strength of AH Plus sealer was significantly decreased (p<0.01) to 2.30 MPa when MTAD was used as chelating agent in Group 3A as compared to other groups where EDTA (Group 1A) or phosphoric acid (Group 2A) was used. Moreover, the use of chelating agents for removal of smear layer yield significantly high mean bond strength values in different groups (Group 1, Group 2, Group 3) as compared to control group (Group 4) where only NS was used (p<0.01). Conclusion: The Bioceramic based Endosequence BC sealer and gutta-percha core combination was not superior in push-out bond strength to AH Plus and gutta-percha core combination. Moreover, use of different organic and inorganic endodontic irrigants influenced the push-out bond strength of both the sealers. Clinical Significance: In dynamic clinical situation, for longer functional viability of an endodontically treated tooth, adhesion of a sealer to root dentin is necessary to avoid its dislocation during tooth flexure and also even during operative procedures like post space preparation. Adequate measures should be undertaken while using different irrigation protocols bearing in mind that the canal irrigants used during chemomechanical preparation can affect root dentin surface, thereby influencing sealer adhesion. Keywords: A-H plus sealer, Bioceramic Sealer, MTAD, Push-out bond Strength, Sodium Hypochlorite.
Micro Push-out Bond Strength and Bioactivity Analysis of a Bioceramic Root Canal Sealer
Iranian endodontic journal, 2017
Bioactive endodontic sealers have been developed to improve the quality of root canal obturation. EndoSequence Bioceramic (BC) Sealer is amongst calcium silicate-based materials recently developed for permanent root canal filling. The objective of this study was to evaluate the bioactivity of BC Sealer and its micro push-out bond strength to dentin compared to AH-Plus (AH) sealer. To perform the micro push-out test, 24 root canals of mandibular premolars were instrumented and divided into two groups (n=12). Each root was cut into 4 slices and lumens of the canals were filled with the sealers and submitted to micro push-out test. Failure mode was assessed using scanning electron microscopy (SEM). Bioactivity of BC sealer was investigated with scanning electron microscopy/energy-dispersive X-ray (SEM/EDS) and X-ray diffraction (XRD). Bioactivity assessments were reported descriptively. Bond strength data were analyzed by parametric t-test (α=5%). In micro push-out test AH had higher b...