original ) (raw )Amphiregulin Promotes Resistance to Gefitinib in NonSmall Cell Lung Cancer Cells by Regulating Ku70 Acetylation
Véronique Josserand , Benoit Busser
Molecular Therapy, 2010
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Amphiregulin Promotes BAX Inhibition and Resistance to Gefitinib in Non-small-cell Lung Cancers
Véronique Josserand , Benoit Busser
Molecular Therapy, 2010
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Cellular targets of gefitinib
Gyorgy Keri
Cancer research, 2005
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Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells
Georg Von Jonquieres
Journal of Biological …, 2008
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Gefitinib upregulates death receptor 5 expression to mediate rmhTRAIL-induced apoptosis in Gefitinib-sensitive NSCLC cell line
Yang Ge
OncoTargets and therapy, 2015
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Amphiregulin Contributes to the Transformed Phenotype of Human Hepatocellular Carcinoma Cells
Mónica Santamaría
Cancer Research, 2006
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The multiple roles of amphiregulin in human cancer
Benoit Busser
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Gefitinib Reverses Chemotherapy Resistance in Gefitinib-Insensitive Multidrug Resistant Cancer Cells Expressing ATP-Binding Cassette Family Protein
Chao-shun Yang
Cancer Research, 2005
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Evolution of the predictive markers amphiregulin and epiregulin mRNAs during long-term cetuximab treatment of KRAS wild-type tumor cells
Ever Castillo
Investigational New Drugs
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Cell survival, cell death and cell cycle pathways are interconnected: Implications for cancer therapy
Soumya Panigrahi , Marek Los
Drug Resistance Updates, 2007
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Influence of gefitinib and erlotinib on apoptosis and c-MYC expression in H23 lung cancer cells
Tatsuhiko Furukawa
Anticancer research, 2013
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Combinatorial treatment of non-small-cell lung cancers with gefitinib and Ad.mda-7 enhances apoptosis-induction and reverses resistance to a single therapy
Irina Lebedeva
Journal of Cellular Physiology, 2007
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Gefitinib induces apoptosis in human glioma cells by targeting Bad phosphorylation
Cheng-Yi Chang
Journal of Neuro-oncology
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Gefitinib Enhances Cytotoxicities of Antimicrotubule Agents in Non–Small-Cell Lung Cancer Cells Exhibiting No Sensitizing Epidermal Growth Factor Receptor Mutation
Chun-liang Lai
Journal of Thoracic Oncology, 2012
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Mechanistic analysis of resistance to REIC/Dkk-3-induced apoptosis in human bladder cancer cells
Masakiyo Sakaguchi
Acta medica Okayama, 2008
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Conditional drug screening shows that mitotic inhibitors induce AKT/PKB-insensitive apoptosis
Maria Shoshan
Journal of Chemical Biology, 2009
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FoxM1 mediated resistance to gefitinib in non-smallcell lung cancer cells
Nuo Xu
Acta Pharmacologica Sinica, 2012
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Unscheduled Akt-Triggered Activation of Cyclin-Dependent Kinase 2 as a Key Effector Mechanism of Apoptin's Anticancer Toxicity
Soumya Panigrahi , Marek Los
Molecular and Cellular Biology, 2008
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Effects of activation of AMPK on human breast cancer cell lines with different genetic backgrounds
Omar Elmasry
Oncology letters, 2012
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Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21
Barbara Bröker
Cancer Research, 2007
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Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation
Katsuyuki Kiura
Cancer Science, 2007
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Gefitinib-Induced Killing of NSCLC Cell Lines Expressing Mutant EGFR Requires BIM and Can Be Enhanced by BH3 Mimetics
Mark Cragg
PLoS Medicine, 2007
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KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib
Marc Ladanyi
PLoS Medicine, 2005
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The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity
Gregory Plowman
Molecular and cellular biology, 1990
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Gefitinib mediates rmhTRAIL-induced apoptosis
Dove Medical Press
2015
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AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest
Carolina Maestre , David Partida , Rosa Pascual
Nature Cell Biology, 2015
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Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma
Amandine Hurbin , Martine Antoine
The Journal of Pathology, 2011
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