Association of Risk Factors With Hepatitis B & C Infection Among Pregnant Women Visiting a Private Tertiary Care Hospitals- Peshawar (An Un Matched Pilot Case Control Study) (original) (raw)
Related papers
2021
Background & aim Hepatitis B and C infections are global issues that are associated with a massive financial burden in developing countries where vertical transmission is the major mode and remains high. This cross-sectional study was designed to investigate the seroepidemiology and associated risk factors of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among 375 pregnant women attending antenatal care health facilities at Bacha Khan Medical Complex (BKMC) Shahmansoor and District Head Quarter (DHQ) Hospital Swabi, Khyber Pakhtunkhwa, Pakistan. Methodology From a total of 375 pregnant women selected using systematic random sampling from both hospitals, 10 ml of blood samples were collected and alienated serum was examined for indicators identification through the Immuno-Chromatographic Test (ICT) and 3rd Generation Enzyme-Linked Immunosorbent Assay (ELISA). A pre-structured questionnaire was used to collect the socio-demographic data and possible risk factors. The ...
Prevalence of Hepatitis B and C Viral Infection Among Pregnant Women in Peshawar, Pakistan
Hepatitis Monthly, 2016
Background: Viral hepatitis during pregnancy is associated with a high risk of maternal complications. The virus has a high risk of vertical transmission and it has been reported as the leading cause of maternal death. Objectives: To study the prevalence of hepatitis B (HBV) and hepatitis C (HCV) viral infections among pregnant women in the Peshawar district of Pakistan. Materials and Methods: The cross-sectional study took place between July 2013 and April 2014. A total of 10,288 samples were collected from pregnant women living in different areas of the Peshawar district. The samples were centrifuged at a high speed in order to obtain a clear supernatant serum. All samples were screened for HBV and HCV using the immunochromatographic technique. Results: The overall prevalence of HBV was found to be 1.16%, although it varied throughout the study period. The highest prevalence of HBV (1.69%) was observed during January 2014. The overall prevalence of HCV infection among the pregnant women was observed to be 1.42%. The highest prevalence of HCV infection (2.22%) was found during March 2014. Conclusions: The overall prevalence of HBV and HCV was 1.16% and 1.42%, respectively. The incidence of HCV infection among the pregnant women was higher than that of HBV infection.
Journal of Medicine, Physiology and Biophysics, 2018
Objective:- To see the frequency of Hepatitis B and Hepatitis C virus infection and associated risk factors in pregnant women. Study design:- Cross-sectional study. Setting:- Outpatient departments of Gynaecology and obstetrics, Nishtar hospital Multan and Bahawal Victoria Hospital (BVH) Bahawalpur. Patients and methods:- A total of 500 pregnant women attending outpatient departments of Gynaecology and Obstetrics were included in this study. Informed consent was taken. A specially designed proforma was filled in. HBsAg and Anti-HCV were tested by device method. Data were analyzed on SPSS-20. Results:- Out of 500 pregnant women 35(7.00%) were found to have Anti-HCV positive and 23(4.60%) were positive for HBsAg. Mean age of the study cases was 26.7± 4.8 years. Majority of the patients 263(52.60%) were from age group 26-35 years. In this study 138 (27.60%) of women were nulliparous and 282 (56.40%) were para 1-4 and Hepatitis B and C were common in this parity group. Only 80 (16.00%)...
Seroprevalence and risk factors of hepatitis B and C infections among pregnant women
International Journal of Research in Medical Sciences
Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are serious public health problem affecting billions of people globally with maternal-fetaltransmission on the rise. This study sought to determine the prevalence and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among pregnant women attending integral institute of medical sciences and research hospital, Lucknow, Uttar Pradesh.Methods: In this cross-sectional study 345 pregnant women were recruited from the integral institute of medical sciences and research hospital, Lucknow, Uttar Pradesh. Blood samples were collected for the detection of Hepatitis B Surface Antigen (HBsAg) and anti-HCV antibodies. A pretested questionnaire was used to obtain demographic data and identify the risk factors associated with the two infections. Ethical clearances were taken from the institution. Data tabulated and subjected to statistical analysis.Results: Out of total 345 samples of pre...
The Professional Medical Journal, 2020
Infectious diseases caused by hepatitis B virus (HBV) and hepatitis C virus (HCV) are a worldwide burden to health, especially in developing countries. Pakistan has one of the highest levels of HBV and HCV infection, causing a severe health problem with significant challenges and priorities. To prevent vertical transmission of infection, regular screening of pregnant women for HBV and HCV is vital. Objectives: The objective of this study was to evaluate the prevalence of HBV and HCV virus in pregnant women having prenatal care. Study Design: Cross-Sectional study. Setting: Bolan Medical Complex Hospital and Sandeman Provincial Civil Hospital Quetta. Period: August 2017 to July 2018. Material & Methods: Blood serum samples were screened for HBV surface antigen (HBsAg) and for anti-HCV using immunochromatography methods. Results: A total of 12,209 pregnant women were tested over a period of one year (August 2017 to July 2018). The overall HBV infections frequency was 1.3% (95% CI 1.1-1.4%) and for HCV infections it was 0.6% (95% CI 0.6-0.7%). Whilst there was only small month-wise variation in the occurrence of HBV and HCV infections, HBV prevalence was highest in May (1.7%) and HCV prevalence was highest in August and December (0.8%). Conclusions: Screening of all pregnant women for HBV and HCV is essential for reducing and eliminating vertical transmission of infection. Risk factors for infection need to be avoided and managed properly.
The prevalence of hepatitis B and C viral infections among pregnant women
North American Journal of Medical Sciences, 2011
Background: Viral hepatitis during pregnancy is associated with high risk of maternal complications and has become a leading cause of foetal death. Aims: This study aimed at determining the prevalence of hepatitis B and C viral infections among pregnant women attending the antenatal clinic of the University of Benin Teaching Hospital. Patients and Methods: This was a hospital based cross-sectional study that included 5760 pregnant women who attended the antenatal clinic of the hospital during the periods of October 2009-October 2010. Relevant data was gathered and women having history of previous liver diseases, diabetes and pre-eclamptic toxemia were excluded from the study. Rapid diagnostic test kits were used to screen for Hepatitis B surface antigen (HBsAg) and anti-Hepatitis C virus (HCV) antibodies. Results: 720 (12.5%) and 206 (3.6%) out of 5,760 pregnant women included in the study were found to be positive for Serum antibodies to hepatitis B and C respectively. 33 (0.57%) were found to have mixed infections of hepatitis B and C. None of the expected risk factors had significant outcome. Conclusion: This study showed that the prevalence of the Hepatitis B virus (HBV) among pregnant women in this study area is of intermediate endemicity (12.5%).
Revista Brasileira de Psiquiatria, 2016
Viral hepatitis during pregnancy is associated with higher risks of maternal complications. The epidemiology of viral hepatitis during pregnancy is essential for health planners and programme managers. This study was conducted to determine the prevalence of HBV & HCV infection in pregnant women. It was a hospital based retrospective study. During the study period; a total of 2450 pregnant females were tested for hepatitis B and C. There were 158 females with positive hepatitis results, out of which 130 were hepatitis C positive and 28 were hepatitis B positive. Only 3 females were those having both hepatitis B and C positive. Average age range of women's was 27-36 years. The data was analyzed by ICT method available at facility of (MCH).We concluded that prevalence of hepatitis B and C in pregnant women is high, of which hepatitis C is more prevalent than hepatitis B and the co-infection of hepatitis B and C was observed as well.
Background. Hepatitis B virus and hepatitis C virus infections are a public health problem worldwide. It is highly endemic in Asia and Sub-Saharan Africa. Horizontal and perinatal transmissions are thought to be the major modes of transmission in these countries. Objective. This study aimed to investigate the seroepidemiology and possible risk factors for hepatitis B virus and hepatitis C virus infection among pregnant women attending antenatal care clinics. Methods. A cross-sectional study design was conducted from July to September 2014 among 421 pregnant women attending antenatal care services in randomly selected health facilities, East Wollega Zone, West Oromia, Ethiopia. Blood sample was collected from each woman and separated serum was tested for the presence of markers. A prestructured questionnaire was used to collect sociodemographic data and risk factors. The collected data was analyzed using SPSS 20.0 statistical software. Odds ratio and 95% confidence interval were used as measures of the strength of association. Result. The overall prevalence of HBsAg was 2.4% ranging from 0.0% to 5.2%. It was the highest in Sire Health Center and the lowest/nil in others. The prevalence of HCV ranged from 6.7% to 20% with an average of 8.07% in this study area where it was highest in the Getema Health Center Antenatal Care Attendants. Only address (p=0.020) and area of the health institution (p=0.021) are significantly the associated factors for HBsAg and serostatus of HCV, respectively. Conclusion. The prevalence of HBsAg carrier rate of pregnant women in the study area falls within the medium endemic prevalence and HCV prevalence was higher than HBsAg. Study participants who were from urban areas were significantly affected with HBV while study institution affects the prevalence of HCV infection so that initiating screening tests during follow up period for antenatal care services is mandatory.
Journal of Advances in Microbiology
Hepatitis infections are global public health concern more especially hepatitis B virus (HBV) and hepatitis C virus (HCV) infections which can easily be transmitted from mothers to newborn babies through contact with body secretions. This research was conducted to investigate the prevalence of Viral Hepatitis B and C infections among pregnant women in Dalhatu Araf Specialist Hospital Lafia, Nasarawa State. Cross sectional study design was carried out from January 2017 to December 2017 among 374 pregnant women. Blood sample was collected from each pregnant woman and screened using enzyme-linked immunosorbent assay (ELISA) kit produced by Nantong Diagnos Biotechnology Co., Ltd., China. Overall prevalence infections of viral hepatitis B and C among the participant was 35(9.4%) and 18(4.8%) respectively. Hepatitis B prevalence was higher than Hepatitis C (P>0.05). Some of the pregnant women were found to be multi-gravida patients ranged from 20-29 years of age with prevalence of 9.6%...